STRINGSTRING
RAC1 RAC1 FRS2 FRS2 LOC100605369 LOC100605369 PIK3R1 PIK3R1 ENSNLEP00000027935 ENSNLEP00000027935 ENSNLEP00000027584 ENSNLEP00000027584 ENSNLEP00000024736 ENSNLEP00000024736 ERAS ERAS BDNF BDNF SOS1 SOS1 SRC SRC ENSNLEP00000046563 ENSNLEP00000046563 ENSNLEP00000043688 ENSNLEP00000043688 ENSNLEP00000042609 ENSNLEP00000042609 FYN FYN GRB2 GRB2 NRAS NRAS ENSNLEP00000039370 ENSNLEP00000039370 DOCK3 DOCK3 TIAM1 TIAM1 NTRK2 NTRK2 GRIN2B GRIN2B CDK5 CDK5 FRS3 FRS3 NTF4 NTF4 KRAS KRAS GAB1 GAB1 PIK3CA PIK3CA PLCG1 PLCG1 HRAS HRAS SHC1 SHC1 ENSNLEP00000036861 ENSNLEP00000036861
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAC1Rac family small GTPase 1. (187 aa)
FRS2Fibroblast growth factor receptor substrate 2. (522 aa)
LOC100605369Uncharacterized protein. (571 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
ENSNLEP00000027935Uncharacterized protein. (181 aa)
ENSNLEP00000027584SH2 domain-containing protein. (188 aa)
ENSNLEP00000024736Uncharacterized protein. (489 aa)
ERASES cell expressed Ras. (233 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
SRCTyrosine-protein kinase. (537 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
ENSNLEP00000043688Uncharacterized protein. (273 aa)
ENSNLEP00000042609Uncharacterized protein. (168 aa)
FYNTyrosine-protein kinase. (537 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (1987 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1561 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1335 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
SHC1SHC adaptor protein 1. (542 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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