Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO1 | AGO2 | ENSNLEP00000013638 | ENSNLEP00000001761 | Argonaute RISC component 1; Belongs to the argonaute family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.997 |
| AGO1 | AGO3 | ENSNLEP00000013638 | ENSNLEP00000013603 | Argonaute RISC component 1; Belongs to the argonaute family. | Argonaute RISC catalytic component 3; Belongs to the argonaute family. | 0.934 |
| AGO1 | AGO4 | ENSNLEP00000013638 | ENSNLEP00000013572 | Argonaute RISC component 1; Belongs to the argonaute family. | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | 0.877 |
| AGO1 | DDX5 | ENSNLEP00000013638 | ENSNLEP00000044468 | Argonaute RISC component 1; Belongs to the argonaute family. | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | 0.418 |
| AGO1 | ENSNLEP00000043017 | ENSNLEP00000013638 | ENSNLEP00000043017 | Argonaute RISC component 1; Belongs to the argonaute family. | HATPase_c domain-containing protein. | 0.601 |
| AGO1 | ENSNLEP00000043421 | ENSNLEP00000013638 | ENSNLEP00000043421 | Argonaute RISC component 1; Belongs to the argonaute family. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.602 |
| AGO1 | HDAC1 | ENSNLEP00000013638 | ENSNLEP00000003167 | Argonaute RISC component 1; Belongs to the argonaute family. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.602 |
| AGO1 | HSP90AA1 | ENSNLEP00000013638 | ENSNLEP00000025829 | Argonaute RISC component 1; Belongs to the argonaute family. | Heat shock protein 90 alpha family class A member 1. | 0.741 |
| AGO1 | HSP90AB1 | ENSNLEP00000013638 | ENSNLEP00000027651 | Argonaute RISC component 1; Belongs to the argonaute family. | Heat shock protein 90 alpha family class B member 1. | 0.601 |
| AGO1 | MOV10 | ENSNLEP00000013638 | ENSNLEP00000005118 | Argonaute RISC component 1; Belongs to the argonaute family. | Mov10 RISC complex RNA helicase. | 0.838 |
| AGO1 | MYC | ENSNLEP00000013638 | ENSNLEP00000006740 | Argonaute RISC component 1; Belongs to the argonaute family. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. | 0.510 |
| AGO1 | POLR2A | ENSNLEP00000013638 | ENSNLEP00000011555 | Argonaute RISC component 1; Belongs to the argonaute family. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.548 |
| AGO1 | POLR2B | ENSNLEP00000013638 | ENSNLEP00000010889 | Argonaute RISC component 1; Belongs to the argonaute family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.415 |
| AGO1 | POLR2C | ENSNLEP00000013638 | ENSNLEP00000003673 | Argonaute RISC component 1; Belongs to the argonaute family. | RNA polymerase II subunit C. | 0.485 |
| AGO1 | TNRC6B | ENSNLEP00000013638 | ENSNLEP00000034946 | Argonaute RISC component 1; Belongs to the argonaute family. | Trinucleotide repeat containing adaptor 6B. | 0.966 |
| AGO2 | AGO1 | ENSNLEP00000001761 | ENSNLEP00000013638 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Argonaute RISC component 1; Belongs to the argonaute family. | 0.997 |
| AGO2 | AGO3 | ENSNLEP00000001761 | ENSNLEP00000013603 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Argonaute RISC catalytic component 3; Belongs to the argonaute family. | 0.987 |
| AGO2 | AGO4 | ENSNLEP00000001761 | ENSNLEP00000013572 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. | 0.950 |
| AGO2 | CCND1 | ENSNLEP00000001761 | ENSNLEP00000031892 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Cyclin D1; Belongs to the cyclin family. | 0.497 |
| AGO2 | DDX5 | ENSNLEP00000001761 | ENSNLEP00000044468 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | 0.708 |
page 1 of 436