STRINGSTRING
ENSNLEP00000046563 ENSNLEP00000046563 PTPRO PTPRO NTF3 NTF3 NRAS NRAS ERAS ERAS PTPRS PTPRS PIK3R1 PIK3R1 IRS1 IRS1 FNDC3A FNDC3A ENSNLEP00000039370 ENSNLEP00000039370 GRB2 GRB2 SRC SRC SHC1 SHC1 NTRK3 NTRK3 NELFB NELFB HRAS HRAS PLCG1 PLCG1 PIK3CA PIK3CA FNDC3B FNDC3B SOS1 SOS1 KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSNLEP00000046563Uncharacterized protein. (498 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1183 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (268 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ERASES cell expressed Ras. (233 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1924 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
IRS1Insulin receptor substrate 1. (1242 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
SRCTyrosine-protein kinase. (537 aa)
SHC1SHC adaptor protein 1. (542 aa)
NTRK3Tyrosine-protein kinase receptor. (706 aa)
NELFBUncharacterized protein. (544 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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