STRINGSTRING
FLT3 FLT3 SYK SYK SH2B3 SH2B3 BCL2L11 BCL2L11 LCK LCK FLT3LG FLT3LG KRAS KRAS SOCS2 SOCS2 PIK3CA PIK3CA SLA SLA SLA2 SLA2 CBL CBL GAB4 GAB4 HRAS HRAS HCK HCK STAT5B STAT5B CSK CSK PTPRJ PTPRJ ABL2 ABL2 SOS1 SOS1 GAB2 GAB2 SOCS6 SOCS6 ERAS ERAS RPS27A-2 RPS27A-2 FOXO3 FOXO3 AKT3 AKT3 M3ZBW0_NOMLE M3ZBW0_NOMLE CDKN1B CDKN1B ENSNLEP00000024736 ENSNLEP00000024736 ENSNLEP00000027584 ENSNLEP00000027584 AKT1 AKT1 ENSNLEP00000028656 ENSNLEP00000028656 PIK3R1 PIK3R1 ENSNLEP00000034619 ENSNLEP00000034619 LOC100605369 LOC100605369 GRAP2 GRAP2 ENSNLEP00000037583 ENSNLEP00000037583 CSDE1 CSDE1 ENSNLEP00000038579 ENSNLEP00000038579 GRB10 GRB10 ENSNLEP00000038869 ENSNLEP00000038869 NRAS NRAS GRB2 GRB2 FYN FYN AKT2 AKT2 ENSNLEP00000043688 ENSNLEP00000043688 RPS27A RPS27A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
SYKTyrosine-protein kinase. (532 aa)
SH2B3SH2B adaptor protein 3. (567 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
LCKLCK proto-oncogene, Src family tyrosine kinase. (448 aa)
FLT3LGUncharacterized protein. (223 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
SOCS2Suppressor of cytokine signaling 2. (176 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
SLASrc like adaptor. (315 aa)
SLA2Src like adaptor 2. (261 aa)
CBLCbl proto-oncogene. (905 aa)
GAB4GRB2 associated binding protein family member 4. (575 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
HCKTyrosine-protein kinase. (525 aa)
STAT5BSignal transducer and activator of transcription. (650 aa)
CSKTyrosine-protein kinase. (274 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1282 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
GAB2GRB2 associated binding protein 2. (651 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
ERASES cell expressed Ras. (233 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
FOXO3Forkhead box O3. (672 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
M3ZBW0_NOMLESH2 domain-containing protein. (230 aa)
CDKN1BUncharacterized protein. (204 aa)
ENSNLEP00000024736Uncharacterized protein. (489 aa)
ENSNLEP00000027584SH2 domain-containing protein. (188 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
ENSNLEP00000028656Uncharacterized protein. (436 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
LOC100605369Uncharacterized protein. (571 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
CSDE1Cold shock domain containing E1. (844 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
GRB10Growth factor receptor bound protein 10. (612 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
FYNTyrosine-protein kinase. (537 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
ENSNLEP00000043688Uncharacterized protein. (273 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (18%) [HD]