47 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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protein homology

Your Input:
	FLT3	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
	SYK	Tyrosine-protein kinase. (532 aa)
	SH2B3	SH2B adaptor protein 3. (567 aa)
	BCL2L11	Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
	LCK	LCK proto-oncogene, Src family tyrosine kinase. (448 aa)
	FLT3LG	Uncharacterized protein. (223 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	SOCS2	Suppressor of cytokine signaling 2. (176 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	SLA	Src like adaptor. (315 aa)
	SLA2	Src like adaptor 2. (261 aa)
	CBL	Cbl proto-oncogene. (905 aa)
	GAB4	GRB2 associated binding protein family member 4. (575 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	HCK	Tyrosine-protein kinase. (525 aa)
	STAT5B	Signal transducer and activator of transcription. (650 aa)
	CSK	Tyrosine-protein kinase. (274 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1282 aa)
	ABL2	Tyrosine-protein kinase. (1182 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
	GAB2	GRB2 associated binding protein 2. (651 aa)
	SOCS6	Suppressor of cytokine signaling 6. (535 aa)
	ERAS	ES cell expressed Ras. (233 aa)
	RPS27A-2	Ubiquitin-like domain-containing protein. (156 aa)
	FOXO3	Forkhead box O3. (672 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	M3ZBW0_NOMLE	SH2 domain-containing protein. (230 aa)
	CDKN1B	Uncharacterized protein. (204 aa)
	ENSNLEP00000024736	Uncharacterized protein. (489 aa)
	ENSNLEP00000027584	SH2 domain-containing protein. (188 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
	ENSNLEP00000028656	Uncharacterized protein. (436 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
	ENSNLEP00000034619	Ubiquitin-like domain-containing protein. (77 aa)
	LOC100605369	Uncharacterized protein. (571 aa)
	GRAP2	GRB2 related adaptor protein 2. (330 aa)
	ENSNLEP00000037583	Ubiquitin-like domain-containing protein. (79 aa)
	CSDE1	Cold shock domain containing E1. (844 aa)
	ENSNLEP00000038579	Ubiquitin-like domain-containing protein. (104 aa)
	GRB10	Growth factor receptor bound protein 10. (612 aa)
	ENSNLEP00000038869	Ubiquitin-like domain-containing protein. (156 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
	ENSNLEP00000043688	Uncharacterized protein. (273 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (161 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL2	CBL	ENSNLEP00000018934	ENSNLEP00000009017	Tyrosine-protein kinase.	Cbl proto-oncogene.	0.599
ABL2	CDKN1B	ENSNLEP00000018934	ENSNLEP00000024488	Tyrosine-protein kinase.	Uncharacterized protein.	0.520
ABL2	FLT3	ENSNLEP00000018934	ENSNLEP00000000457	Tyrosine-protein kinase.	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.499
ABL2	GRAP2	ENSNLEP00000018934	ENSNLEP00000036468	Tyrosine-protein kinase.	GRB2 related adaptor protein 2.	0.407
ABL2	GRB2	ENSNLEP00000018934	ENSNLEP00000040743	Tyrosine-protein kinase.	Growth factor receptor bound protein 2.	0.634
ABL2	M3ZBW0_NOMLE	ENSNLEP00000018934	ENSNLEP00000024197	Tyrosine-protein kinase.	SH2 domain-containing protein.	0.436
ABL2	PIK3R1	ENSNLEP00000018934	ENSNLEP00000031935	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 1.	0.413
ABL2	STAT5B	ENSNLEP00000018934	ENSNLEP00000013916	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.446
AKT1	AKT2	ENSNLEP00000028045	ENSNLEP00000042041	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.891
AKT1	AKT3	ENSNLEP00000028045	ENSNLEP00000023896	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.950
AKT1	BCL2L11	ENSNLEP00000028045	ENSNLEP00000002811	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family.	0.617
AKT1	CBL	ENSNLEP00000028045	ENSNLEP00000009017	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cbl proto-oncogene.	0.667
AKT1	CDKN1B	ENSNLEP00000028045	ENSNLEP00000024488	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.996
AKT1	CSK	ENSNLEP00000028045	ENSNLEP00000017774	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.474
AKT1	ENSNLEP00000043688	ENSNLEP00000028045	ENSNLEP00000043688	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.596
AKT1	ERAS	ENSNLEP00000028045	ENSNLEP00000022477	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	ES cell expressed Ras.	0.424
AKT1	FLT3	ENSNLEP00000028045	ENSNLEP00000000457	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.534
AKT1	FOXO3	ENSNLEP00000028045	ENSNLEP00000023641	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box O3.	0.991
AKT1	FYN	ENSNLEP00000028045	ENSNLEP00000041056	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.706
AKT1	GRB10	ENSNLEP00000028045	ENSNLEP00000038650	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Growth factor receptor bound protein 10.	0.416

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