STRINGSTRING
GNG2 GNG2 GNB1 GNB1 SYK SYK GGT5 GGT5 ADCY7 ADCY7 ADCY3 ADCY3 LYN LYN CYSLTR1 CYSLTR1 RHBDF2 RHBDF2 LOC101178534 LOC101178534 PLK2 PLK2 GNG8 GNG8 GNGT2 GNGT2 AHCYL1 AHCYL1 ITPR1 ITPR1 GNG3 GNG3 G1QVV4_NOMLE G1QVV4_NOMLE DPEP3 DPEP3 DPEP2 DPEP2 CD163 CD163 GNB4 GNB4 PLCG1 PLCG1 YES1 YES1 GNAI2 GNAI2 CREB1 CREB1 CD3G CD3G RHBDF1 RHBDF1 PRKAR1B PRKAR1B PRKX PRKX GNAS GNAS GNAI1 GNAI1 HCK HCK GNG5 GNG5 PLCG2 PLCG2 ADCY2 ADCY2 GNB2 GNB2 FURIN FURIN ADAM17 ADAM17 FCGR2A FCGR2A MYH9 MYH9 GNAT3 GNAT3 CD247 CD247 ADORA2B ADORA2B G1RZK2_NOMLE G1RZK2_NOMLE GNGT1 GNGT1 GNG11 GNG11 ADCY4 ADCY4 GNAZ GNAZ LOC100593662 LOC100593662 G1S049_NOMLE G1S049_NOMLE DPEP1 DPEP1 MAPK14 MAPK14 PRKACA PRKACA GNG13 GNG13 GNG4 GNG4 LOC100586578 LOC100586578 ENSNLEP00000028868 ENSNLEP00000028868 PRKACB PRKACB GNB3 GNB3 ADCY6 ADCY6 GNB5 GNB5 PRKAR2A PRKAR2A LOC100592070 LOC100592070 PRKAR2B PRKAR2B ADCY9 ADCY9 FGR FGR IL10 IL10 ITPR2 ITPR2 PRKACG PRKACG ADCY8 ADCY8 GNG12 GNG12 GNG7 GNG7 ITPR3 ITPR3 GGT1 GGT1 FYN FYN GNAI3 GNAI3 PRKAR1A PRKAR1A ENSNLEP00000046477 ENSNLEP00000046477 ADCY1 ADCY1 IL6 IL6 ADCY5 ADCY5 SRC SRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
GNB1G protein subunit beta 1. (340 aa)
SYKTyrosine-protein kinase. (532 aa)
GGT5Gamma-glutamyltransferase 5. (509 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (983 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
LYNTyrosine-protein kinase. (512 aa)
CYSLTR1Cysteinyl leukotriene receptor 1. (337 aa)
RHBDF2Rhomboid 5 homolog 2. (751 aa)
LOC101178534Uncharacterized protein. (913 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (529 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
G1QVV4_NOMLEGuanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (292 aa)
DPEP3Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (499 aa)
DPEP2Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (472 aa)
CD163CD163 molecule. (1156 aa)
GNB4G protein subunit beta 4. (340 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1182 aa)
YES1Tyrosine-protein kinase. (519 aa)
GNAI2G protein subunit alpha i2. (355 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CD3GCD3g molecule. (182 aa)
RHBDF1Rhomboid 5 homolog 1. (858 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (320 aa)
PRKXProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (318 aa)
GNASGNAS complex locus. (1038 aa)
GNAI1G protein subunit alpha i1. (353 aa)
HCKTyrosine-protein kinase. (525 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (966 aa)
GNB2G protein subunit beta 2. (325 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (785 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
FCGR2AFc fragment of IgG receptor IIa. (317 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1975 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
CD247CD247 molecule. (163 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (329 aa)
G1RZK2_NOMLECyclic nucleotide-binding domain-containing protein. (82 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1026 aa)
GNAZG protein subunit alpha z. (355 aa)
LOC100593662Uncharacterized protein. (225 aa)
G1S049_NOMLEUncharacterized protein. (212 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (367 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
PRKACAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (116 aa)
LOC100586578Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSNLEP00000028868G protein gamma domain-containing protein. (64 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GNB3G protein subunit beta 3. (335 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1055 aa)
GNB5G protein subunit beta 5. (357 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
LOC100592070Uncharacterized protein; Belongs to the protein kinase superfamily. (347 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (343 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1310 aa)
FGRTyrosine-protein kinase. (476 aa)
IL10Interleukin 10. (178 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
PRKACGUncharacterized protein. (290 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2755 aa)
GGT1Uncharacterized protein. (539 aa)
FYNTyrosine-protein kinase. (537 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
ENSNLEP00000046477Uncharacterized protein. (273 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
IL6Uncharacterized protein. (258 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
SRCTyrosine-protein kinase. (537 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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