STRINGSTRING
AMER1 AMER1 MAFG MAFG PRKCD PRKCD IDH1 IDH1 KIAA2012 KIAA2012 PSMB9 PSMB9 PSMB8 PSMB8 TXNRD1 TXNRD1 PSMA8 PSMA8 KLHL18 KLHL18 CSNK2B CSNK2B DPP3 DPP3 KXD1 KXD1 PSMD11 PSMD11 SPATA5L1 SPATA5L1 MYC MYC PSMB10 PSMB10 VCP VCP TRIM58 TRIM58 PSMC5 PSMC5 MTFP1 MTFP1 GSTA1 GSTA1 GSTA3 GSTA3 CUL1 CUL1 GCLC GCLC CSNK2A2 CSNK2A2 BACH1 BACH1 PSMA2 PSMA2 NFE2L1 NFE2L1 SQSTM1 SQSTM1 UBXN7 UBXN7 PSMD3 PSMD3 PSMD9 PSMD9 TXNRD3 TXNRD3 PSMB3 PSMB3 ENSNLEP00000049245 ENSNLEP00000049245 ENSNLEP00000048393 ENSNLEP00000048393 KLHL17 KLHL17 CUL3 CUL3 PSMD13 PSMD13 PRDX1 PRDX1 PSMB7 PSMB7 ENSNLEP00000046239 ENSNLEP00000046239 HMOX1 HMOX1 NFE2L3 NFE2L3 PGD PGD PSMD6 PSMD6 PSME4 PSME4 RPS27A RPS27A PSMB2 PSMB2 PSMD2 PSMD2 UFD1 UFD1 NFE2L2 NFE2L2 ENSNLEP00000042742 ENSNLEP00000042742 ENSNLEP00000042252 ENSNLEP00000042252 BRCA1 BRCA1 AKT2 AKT2 ENSNLEP00000041921 ENSNLEP00000041921 PSMD1 PSMD1 ENSNLEP00000041226 ENSNLEP00000041226 PSMB5 PSMB5 ENSNLEP00000040208 ENSNLEP00000040208 NQO1 NQO1 PSME3 PSME3 ENSNLEP00000039422 ENSNLEP00000039422 ENSNLEP00000039192 ENSNLEP00000039192 ENSNLEP00000039157 ENSNLEP00000039157 ENSNLEP00000038869 ENSNLEP00000038869 ENSNLEP00000038754 ENSNLEP00000038754 ENSNLEP00000038691 ENSNLEP00000038691 ENSNLEP00000038579 ENSNLEP00000038579 ENSNLEP00000038401 ENSNLEP00000038401 NPLOC4 NPLOC4 ENSNLEP00000037880 ENSNLEP00000037880 ENSNLEP00000037583 ENSNLEP00000037583 PSMB6 PSMB6 PSMF1 PSMF1 PSME2 PSME2 RBX1 RBX1 SKP1 SKP1 NOTCH1 NOTCH1 MAFK MAFK PSMC2 PSMC2 EP300 EP300 ENSNLEP00000035546 ENSNLEP00000035546 ENSNLEP00000035481 ENSNLEP00000035481 ENSNLEP00000034619 ENSNLEP00000034619 ENSNLEP00000034390 ENSNLEP00000034390 PSMB1 PSMB1 PSMD7 PSMD7 TKT TKT PSME1 PSME1 PSMD14 PSMD14 ENSNLEP00000032165 ENSNLEP00000032165 ENSNLEP00000031906 ENSNLEP00000031906 PSMD10 PSMD10 LOC100605818 LOC100605818 ENSNLEP00000029825 ENSNLEP00000029825 ENSNLEP00000029811 ENSNLEP00000029811 ENSNLEP00000029611 ENSNLEP00000029611 PSMA4 PSMA4 ENSNLEP00000028992 ENSNLEP00000028992 MUL1 MUL1 PSMA6 PSMA6 PSMA5 PSMA5 SRXN1 SRXN1 AKT1 AKT1 PSMD12 PSMD12 CSNK2A1 CSNK2A1 SPATA5 SPATA5 CREBBP CREBBP PSMD4 PSMD4 PSMB4 PSMB4 GCLM GCLM MAP1LC3B MAP1LC3B GSR GSR PALB2 PALB2 KEAP1 KEAP1 SESN1 SESN1 PSMC6 PSMC6 ME1 ME1 PSMA3 PSMA3 SLC7A11 SLC7A11 PSMC4 PSMC4 G6PD G6PD PSMC3 PSMC3 BTRC BTRC ATF4 ATF4 PSMA7 PSMA7 SKP2 SKP2 PSMD8 PSMD8 PSMC1 PSMC1 PSMD5 PSMD5 TRIM21 TRIM21 RPS27A-2 RPS27A-2 BACH2 BACH2 AKT3 AKT3 SESN2 SESN2 PSMA1 PSMA1 ENSNLEP00000025290 ENSNLEP00000025290 ENSNLEP00000026115 ENSNLEP00000026115 GSK3B GSK3B LOC100591996 LOC100591996
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMER1Uncharacterized protein. (805 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (397 aa)
KIAA2012KIAA2012. (1116 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (276 aa)
TXNRD1Thioredoxin reductase 1. (647 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
KLHL18Kelch like family member 18. (521 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (227 aa)
DPP3Dipeptidyl peptidase 3; Belongs to the peptidase M49 family. (757 aa)
KXD1KxDL motif containing 1. (195 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
SPATA5L1AAA domain-containing protein. (171 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
PSMB10Proteasome subunit beta. (272 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (808 aa)
TRIM58Tripartite motif containing 58. (486 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
MTFP1Mitochondrial fission process 1. (163 aa)
GSTA1Glutathione S-transferase alpha 1. (222 aa)
GSTA3Glutathione S-transferase alpha 3; Belongs to the GST superfamily. (222 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (320 aa)
BACH1BTB domain and CNC homolog 1. (736 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (757 aa)
SQSTM1UBA_5 domain-containing protein. (197 aa)
UBXN7UBX domain-containing protein 7. (484 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (528 aa)
PSMD9PDZ domain-containing protein. (222 aa)
TXNRD3Thioredoxin reductase 3. (561 aa)
PSMB3Proteasome subunit beta. (205 aa)
ENSNLEP00000049245AAA domain-containing protein. (394 aa)
ENSNLEP00000048393VWFA domain-containing protein. (326 aa)
KLHL17Kelch like family member 17. (668 aa)
CUL3Cullin 3; Belongs to the cullin family. (744 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (397 aa)
PRDX1Peroxiredoxin 1. (199 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSNLEP00000046239Prot_ATP_ID_OB domain-containing protein. (183 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
NFE2L3Nuclear factor, erythroid 2 like 3. (660 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (481 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
PSME4Proteasome activator subunit 4. (1821 aa)
RPS27AUbiquitin-like domain-containing protein. (161 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (312 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (607 aa)
ENSNLEP00000042742Proteasome subunit alpha type. (233 aa)
ENSNLEP00000042252Uncharacterized protein; Belongs to the SKP1 family. (137 aa)
BRCA1BRCA1 DNA repair associated. (1884 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
ENSNLEP00000041921Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (385 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
ENSNLEP00000041226ATPase_AAA_core domain-containing protein. (461 aa)
PSMB5Proteasome subunit beta. (263 aa)
ENSNLEP00000040208AAA domain-containing protein. (406 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (261 aa)
PSME3Proteasome activator subunit 3. (239 aa)
ENSNLEP00000039422Ubiquitin-like domain-containing protein. (136 aa)
ENSNLEP00000039192Uncharacterized protein. (179 aa)
ENSNLEP00000039157CSN8_PSD8_EIF3K domain-containing protein. (225 aa)
ENSNLEP00000038869Ubiquitin-like domain-containing protein. (156 aa)
ENSNLEP00000038754F-box domain-containing protein. (392 aa)
ENSNLEP000000386911-cysPrx_C domain-containing protein. (97 aa)
ENSNLEP00000038579Ubiquitin-like domain-containing protein. (104 aa)
ENSNLEP00000038401ANK_REP_REGION domain-containing protein. (141 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (607 aa)
ENSNLEP00000037880Uncharacterized protein. (341 aa)
ENSNLEP00000037583Ubiquitin-like domain-containing protein. (79 aa)
PSMB6Proteasome subunit beta. (244 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSME2Proteasome activator subunit 2. (256 aa)
RBX1Ring-box 1. (108 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
NOTCH1Notch receptor 1. (2451 aa)
MAFKMAF bZIP transcription factor K. (156 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
EP300E1A binding protein p300. (2306 aa)
ENSNLEP00000035546Uncharacterized protein. (50 aa)
ENSNLEP00000035481Uncharacterized protein. (73 aa)
ENSNLEP00000034619Ubiquitin-like domain-containing protein. (77 aa)
ENSNLEP00000034390Uncharacterized protein. (111 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
TKTTransketolase. (580 aa)
PSME1Proteasome activator subunit 1. (250 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (315 aa)
ENSNLEP00000032165BZIP domain-containing protein. (648 aa)
ENSNLEP00000031906Uncharacterized protein. (406 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
LOC100605818BZIP domain-containing protein. (347 aa)
ENSNLEP00000029825Uncharacterized protein. (351 aa)
ENSNLEP00000029811Uncharacterized protein; Belongs to the SKP1 family. (146 aa)
ENSNLEP00000029611Proteasome subunit beta. (202 aa)
PSMA4Proteasome subunit alpha type. (241 aa)
ENSNLEP00000028992Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (389 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (338 aa)
PSMA6Proteasome subunit alpha type. (206 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
SRXN1Sulfiredoxin. (161 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (488 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
SPATA5Spermatogenesis associated 5. (879 aa)
CREBBPCREB binding protein. (2442 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
MAP1LC3BUncharacterized protein. (125 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)
PALB2Partner and localizer of BRCA2. (1186 aa)
KEAP1BTB domain-containing protein. (395 aa)
SESN1Sestrin 1. (551 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
ME1Malic enzyme. (572 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
SLC7A11Solute carrier family 7 member 11. (500 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (421 aa)
G6PDUncharacterized protein. (452 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
ATF4BZIP domain-containing protein. (351 aa)
PSMA7Proteasome subunit alpha type. (265 aa)
SKP2S-phase kinase associated protein 2. (425 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (350 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (509 aa)
TRIM21Tripartite motif containing 21. (475 aa)
RPS27A-2Ubiquitin-like domain-containing protein. (156 aa)
BACH2BTB domain and CNC homolog 2. (841 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
SESN2Sestrin 2. (470 aa)
PSMA1Proteasome subunit alpha type. (268 aa)
ENSNLEP00000025290Uncharacterized protein. (239 aa)
ENSNLEP00000026115AAA domain-containing protein. (339 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
LOC100591996Proteasome endopeptidase complex. (164 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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