STRINGSTRING
ATXN2 ATXN2 SCO2 SCO2 SCARB1 SCARB1 LDHA LDHA SUMO2 SUMO2 AURKB AURKB BIRC2 BIRC2 CIAPIN1-2 CIAPIN1-2 RNF4 RNF4 WDR35 WDR35 PARP10 PARP10 CIAPIN1 CIAPIN1 NCAPD2 NCAPD2 RAD18 RAD18 GAPDH GAPDH XRCC5 XRCC5 SLX4 SLX4 SDR42E1 SDR42E1 PFKP PFKP FOXP2 FOXP2 NAGLU NAGLU ZWINT ZWINT FDPS FDPS PRKDC PRKDC KIF23 KIF23 TRMT6 TRMT6 FASN FASN CUL3 CUL3 SUMO1 SUMO1 DSC3 DSC3 SNAP23 SNAP23 RARA RARA MCM5 MCM5 LOC101179053 LOC101179053 NGDN NGDN MYO6 MYO6 FANCA FANCA NEDD8 NEDD8 NUP205 NUP205 G1SAI6_NOMLE G1SAI6_NOMLE PIK3C2A PIK3C2A AKAP12 AKAP12 LRPPRC LRPPRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATXN2Ataxin 2. (1249 aa)
SCO2SCO cytochrome c oxidase assembly protein 2. (266 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (550 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
AURKBUncharacterized protein. (123 aa)
BIRC2Baculoviral IAP repeat containing 2. (615 aa)
CIAPIN1-2Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (297 aa)
RNF4Ring finger protein 4. (190 aa)
WDR35WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. (1181 aa)
PARP10Poly [ADP-ribose] polymerase. (1036 aa)
CIAPIN1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (312 aa)
NCAPD2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1401 aa)
RAD18RAD18 E3 ubiquitin protein ligase. (494 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
SLX4SLX4 structure-specific endonuclease subunit. (1821 aa)
SDR42E1Short chain dehydrogenase/reductase family 42E, member 1; Belongs to the 3-beta-HSD family. (393 aa)
PFKP6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (783 aa)
FOXP2Forkhead box P2. (739 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (713 aa)
ZWINTZW10 interacting kinetochore protein. (281 aa)
FDPSFarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (420 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit. (3853 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (960 aa)
TRMT6tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; Substrate-binding subunit of tRNA (adenine-N1-)- methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. (497 aa)
FASNCarrier domain-containing protein. (2417 aa)
CUL3Cullin 3; Belongs to the cullin family. (744 aa)
SUMO1Small ubiquitin-related modifier. (88 aa)
DSC3Desmocollin 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (896 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
RARARetinoic acid receptor alpha. (458 aa)
MCM5DNA helicase; Belongs to the MCM family. (722 aa)
LOC101179053Small ubiquitin-related modifier. (94 aa)
NGDNNeuroguidin. (315 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
FANCAFA complementation group A. (1416 aa)
NEDD8NEDD8 ubiquitin like modifier. (81 aa)
NUP205Nucleoporin 205. (2017 aa)
G1SAI6_NOMLESmall ubiquitin-related modifier. (100 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa)
AKAP12A-kinase anchoring protein 12. (1779 aa)
LRPPRCPPR_long domain-containing protein. (1379 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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