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NT5C NT5C UMPS UMPS UPP2 UPP2 NT5C1B NT5C1B CAD CAD DPYS DPYS UPP1 UPP1 ENTPD3 ENTPD3 TYMS TYMS CDA CDA NME4 NME4 NME3 NME3 ENTPD8 ENTPD8 CTPS2 CTPS2 PNP PNP NT5C3B NT5C3B DPYD DPYD CTPS1 CTPS1 AK9 AK9 NT5E NT5E ENTPD1 ENTPD1 ENPP3 ENPP3 ENPP1 ENPP1 UCK2 UCK2 NME7 NME7 NT5C3A NT5C3A DCTPP1 DCTPP1 ENTPD5 ENTPD5 CMPK1 CMPK1 RRM1 RRM1 NT5C2 NT5C2 DCTD DCTD NME1-NME2 NME1-NME2 NUDT2 NUDT2 DHODH DHODH ENTPD6 ENTPD6 DCK DCK NME6 NME6 RRM2B RRM2B RRM2 RRM2 UPRT UPRT ENTPD4 ENTPD4 UPB1 UPB1 LOC100582337 LOC100582337 TK2 TK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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NT5C5', 3'-nucleotidase, cytosolic. (201 aa)
UMPSUridine monophosphate synthetase. (481 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (363 aa)
NT5C1BUncharacterized protein. (609 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2200 aa)
DPYSDihydropyrimidinase. (519 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (310 aa)
ENTPD3Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa)
TYMSThymidylat_synt domain-containing protein. (173 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (495 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
AK9Adenylate kinase 9. (1911 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (502 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (827 aa)
UCK2Uridine-cytidine kinase 2. (228 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (376 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (336 aa)
DCTPP1dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (170 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (428 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
NT5C25'-nucleotidase, cytosolic II. (584 aa)
DCTDdCMP deaminase. (178 aa)
NME1-NME2Nucleoside diphosphate kinase. (292 aa)
NUDT2Nudix hydrolase 2. (147 aa)
DHODHDihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (484 aa)
DCKdNK domain-containing protein. (317 aa)
NME6Nucleoside diphosphate kinase. (194 aa)
RRM2BRibonucleotide reductase regulatory TP53 inducible subunit M2B. (355 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (448 aa)
UPRTUncharacterized protein. (173 aa)
ENTPD4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (617 aa)
UPB1Beta-ureidopropionase 1. (384 aa)
LOC100582337Nucleoside diphosphate kinase. (147 aa)
TK2Thymidine kinase 2. (296 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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