STRINGSTRING
TACC3 TACC3 THOC3 THOC3 EIF2S1 EIF2S1 TGS1 TGS1 KPNB1 KPNB1 CASC3 CASC3 GEMIN7 GEMIN7 SAP18 SAP18 EIF3I EIF3I NUP93 NUP93 POP1 POP1 THOC5 THOC5 TRNT1 TRNT1 MAGOHB MAGOHB NUP107 NUP107 XPO5 XPO5 GEMIN2 GEMIN2 PNN PNN NXF1 NXF1 SEC13 SEC13 NUP210 NUP210 RPP25L RPP25L EIF1B EIF1B EIF2B5 EIF2B5 SENP2 SENP2 EIF4A2 EIF4A2 THOC1 THOC1 RANBP2 RANBP2 LOC100598965 LOC100598965 UPF3A UPF3A NXF3 NXF3 NUP54 NUP54 UBE2I UBE2I SEH1L SEH1L EIF4A1 EIF4A1 XPO1 XPO1 EEF1A2 EEF1A2 PAIP1 PAIP1 NUP210L NUP210L EIF1 EIF1 THOC7 THOC7 ELAC1 ELAC1 POP7 POP7 PABPC4 PABPC4 UPF2 UPF2 EIF3G EIF3G PHAX PHAX EIF4E1B EIF4E1B NUP214 NUP214 FMR1 FMR1 EIF5B EIF5B EIF2B3 EIF2B3 NXT2 NXT2 NUP133 NUP133 EIF3D EIF3D NUP160 NUP160 UPF3B UPF3B ACIN1 ACIN1 POM121 POM121 EIF4A3 EIF4A3 POP5 POP5 EIF4EBP2 EIF4EBP2 EIF2B2 EIF2B2 GEMIN5 GEMIN5 CLNS1A CLNS1A XPOT XPOT AAAS AAAS EIF4B EIF4B TPR TPR PABPC1L2A PABPC1L2A EIF2S3B EIF2S3B RPP25 RPP25 G1SAI6_NOMLE G1SAI6_NOMLE EIF3F EIF3F NUP205 NUP205 EIF4G2 EIF4G2 NUP35 NUP35 NUP37 NUP37 LOC100602080 LOC100602080 ENSNLEP00000025820 ENSNLEP00000025820 EIF5 EIF5 MAGOH MAGOH PABPC5 PABPC5 RPP30 RPP30 TARDBP TARDBP PRMT5 PRMT5 GEMIN8 GEMIN8 NUP43 NUP43 FXR1 FXR1 CYFIP2 CYFIP2 CYFIP1 CYFIP1 EIF3H EIF3H THOC6 THOC6 NUP58 NUP58 NCBP1 NCBP1 PYM1 PYM1 SRRM1 SRRM1 LOC100599771 LOC100599771 PABPC4L PABPC4L NUP85 NUP85 PABPC3 PABPC3 EIF4G1 EIF4G1 RPP40 RPP40 NMD3 NMD3 FXR2 FXR2 DDX20 DDX20 NUP50 NUP50 SUMO2 SUMO2 STRAP STRAP ALYREF ALYREF SMN1 SMN1 NUP153 NUP153 ENSNLEP00000043013 ENSNLEP00000043013 EEF1A1 EEF1A1 EIF4E-2 EIF4E-2 PABPC1L PABPC1L RPP14 RPP14 RPP38 RPP38 LOC100604768 LOC100604768 RNPS1 RNPS1 ENSNLEP00000046292 ENSNLEP00000046292 EIF3E EIF3E EIF4E2 EIF4E2 EIF3J EIF3J NUP155-2 NUP155-2 GEMIN6 GEMIN6 ENSNLEP00000047930 ENSNLEP00000047930 NUP42 NUP42 EIF2B1 EIF2B1 RBM8A RBM8A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TACC3Transforming acidic coiled-coil containing protein 3. (807 aa)
THOC3THO complex 3. (350 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
TGS1Trimethylguanosine synthase 1. (855 aa)
KPNB1Karyopherin subunit beta 1. (876 aa)
CASC3CASC3 exon junction complex subunit. (702 aa)
GEMIN7Gem nuclear organelle associated protein 7. (131 aa)
SAP18Sin3A associated protein 18. (172 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (1024 aa)
THOC5THO complex 5. (682 aa)
TRNT1tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (434 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
XPO5Exportin 5. (1167 aa)
GEMIN2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (272 aa)
PNNPinin, desmosome associated protein. (718 aa)
NXF1Uncharacterized protein. (404 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
NUP210Nucleoporin 210. (1889 aa)
RPP25LRibonuclease P/MRP subunit p25 like. (163 aa)
EIF1BEukaryotic translation initiation factor 1B. (113 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (721 aa)
SENP2SUMO specific peptidase 2. (589 aa)
EIF4A2Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (407 aa)
THOC1THO complex 1. (657 aa)
RANBP2RAN binding protein 2. (3183 aa)
LOC100598965Uncharacterized protein. (626 aa)
UPF3AUPF3A regulator of nonsense mediated mRNA decay. (477 aa)
NXF3Nuclear RNA export factor 3. (531 aa)
NUP54Nucleoporin 54. (508 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (190 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (360 aa)
EIF4A1Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family. (408 aa)
XPO1Exportin 1. (1091 aa)
EEF1A2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
PAIP1Poly(A) binding protein interacting protein 1. (424 aa)
NUP210LNucleoporin 210 like. (1845 aa)
EIF1Eukaryotic translation initiation factor 1. (113 aa)
THOC7THO complex 7. (204 aa)
ELAC1ElaC ribonuclease Z 1. (363 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (644 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1272 aa)
EIF3GEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa)
PHAXPhosphorylated adaptor for RNA export. (362 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (241 aa)
NUP214Nucleoporin 214. (2089 aa)
FMR1Fragile X mental retardation 1. (632 aa)
EIF5BEukaryotic translation initiation factor 5B. (1220 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (435 aa)
NXT2Nuclear transport factor 2 like export factor 2. (197 aa)
NUP133Nucleoporin 133. (1156 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (548 aa)
NUP160Nucleoporin 160. (1436 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (482 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1342 aa)
POM121Uncharacterized protein. (834 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
POP5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (164 aa)
EIF4EBP2Uncharacterized protein. (120 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1507 aa)
CLNS1AChloride nucleotide-sensitive channel 1A. (237 aa)
XPOTExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (962 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
EIF4BEukaryotic translation initiation factor 4B. (612 aa)
TPRTranslocated promoter region, nuclear basket protein. (2354 aa)
PABPC1L2AUncharacterized protein. (200 aa)
EIF2S3BTr-type G domain-containing protein. (339 aa)
RPP25Ribonuclease P and MRP subunit p25. (199 aa)
G1SAI6_NOMLESmall ubiquitin-related modifier. (100 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (367 aa)
NUP205Nucleoporin 205. (2017 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (980 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (326 aa)
NUP37Nucleoporin 37. (326 aa)
LOC100602080Rad60-SLD domain-containing protein. (74 aa)
ENSNLEP00000025820Rad60-SLD domain-containing protein. (80 aa)
EIF5Eukaryotic translation initiation factor 5. (431 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
RPP30Ribonuclease P/MRP subunit p30. (320 aa)
TARDBPUncharacterized protein. (414 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (633 aa)
GEMIN8Gem nuclear organelle associated protein 8. (242 aa)
NUP43Nucleoporin 43. (380 aa)
FXR1FMR1 autosomal homolog 1. (661 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1228 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (366 aa)
THOC6THO complex 6. (341 aa)
NUP58Nucleoporin 58. (599 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
PYM1PYM homolog 1, exon junction complex associated factor. (211 aa)
SRRM1Serine and arginine repetitive matrix 1. (913 aa)
LOC100599771GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (370 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (659 aa)
PABPC3Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (631 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1558 aa)
RPP40Ribonuclease P/MRP subunit p40. (363 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (529 aa)
FXR2FMR1 autosomal homolog 2. (657 aa)
DDX20DEAD-box helicase 20. (824 aa)
NUP50RanBD1 domain-containing protein. (469 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
STRAPSerine/threonine kinase receptor associated protein. (364 aa)
ALYREFAly/REF export factor. (285 aa)
SMN1Tudor domain-containing protein. (294 aa)
NUP153Nucleoporin 153. (1506 aa)
ENSNLEP00000043013eIF2B_5 domain-containing protein. (290 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
EIF4E-2Uncharacterized protein. (77 aa)
PABPC1LPABC domain-containing protein. (171 aa)
RPP14Ribonuclease P/MRP subunit p14. (124 aa)
RPP38Uncharacterized protein. (144 aa)
LOC100604768Uncharacterized protein. (72 aa)
RNPS1RNA binding protein with serine rich domain 1. (272 aa)
ENSNLEP00000046292Rad60-SLD domain-containing protein. (63 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (463 aa)
EIF4E2Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
EIF3JEukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (259 aa)
NUP155-2Nuclear pore complex protein Nup155 isoform X1. (54 aa)
GEMIN6Gem nuclear organelle associated protein 6. (167 aa)
ENSNLEP00000047930Tr-type G domain-containing protein. (452 aa)
NUP42Nucleoporin 42. (423 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (305 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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