STRINGSTRING
RFC5 RFC5 CUL4A CUL4A RFC3 RFC3 DDB1 DDB1 ERCC8 ERCC8 LOC100582721 LOC100582721 XPC XPC GTF2H4 GTF2H4 POLD1 POLD1 RFC4 RFC4 PCNA PCNA XPA XPA RPA2 RPA2 ERCC4 ERCC4 POLE2 POLE2 MNAT1 MNAT1 ERCC3 ERCC3 ERCC6 ERCC6 POLE3 POLE3 RFC1 RFC1 RPA1 RPA1 RAD23B RAD23B GTF2H1 GTF2H1 ERCC5 ERCC5 POLD3 POLD3 POLE POLE CETN2 CETN2 GTF2H5 GTF2H5 POLE4 POLE4 POLD4 POLD4 RBX1 RBX1 POLD2 POLD2 GTF2H3 GTF2H3 CCNH CCNH CUL4B CUL4B RPA3 RPA3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFC5Replication factor C subunit 5. (354 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
RFC3Replication factor C subunit 3. (356 aa)
DDB1Damage specific DNA binding protein 1. (1139 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
LOC100582721General transcription factor IIH subunit. (395 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (929 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLD1DNA polymerase. (1062 aa)
RFC4Replication factor C subunit 4. (363 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
XPAXPA, DNA damage recognition and repair factor. (264 aa)
RPA2Replication protein A2. (270 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (890 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (737 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1492 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
RFC1Replication factor C subunit 1. (1130 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
ERCC5BIVM-ERCC5 readthrough. (1483 aa)
POLD3Uncharacterized protein. (463 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2264 aa)
CETN2Centrin 2. (172 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (116 aa)
POLD4Uncharacterized protein. (51 aa)
RBX1Ring-box 1. (108 aa)
POLD2DNA polymerase delta 2, accessory subunit. (498 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
CUL4BCullin 4B; Belongs to the cullin family. (913 aa)
RPA3Replication protein A3. (121 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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