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MAPKAPK5 | MAPK activated protein kinase 5. (471 aa) | ||||
CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) | ||||
CACNG1 | Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa) | ||||
CACNG5 | Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa) | ||||
PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa) | ||||
TAOK3 | TAO kinase 3. (898 aa) | ||||
FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa) | ||||
GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (368 aa) | ||||
CRK | Uncharacterized protein. (252 aa) | ||||
MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (370 aa) | ||||
FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) | ||||
FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (391 aa) | ||||
PAK2 | Non-specific serine/threonine protein kinase. (524 aa) | ||||
RELB | RELB proto-oncogene, NF-kB subunit. (586 aa) | ||||
NLK | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) | ||||
MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1461 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (764 aa) | ||||
FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) | ||||
RPS6KA6 | Ribosomal protein S6 kinase. (738 aa) | ||||
PPP5C | Serine/threonine-protein phosphatase. (499 aa) | ||||
FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) | ||||
FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (268 aa) | ||||
CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa) | ||||
DUSP16 | Dual specificity phosphatase 16. (662 aa) | ||||
NTRK2 | Tyrosine-protein kinase receptor. (838 aa) | ||||
PLA2G4E | Phospholipase A2. (867 aa) | ||||
PLA2G4D | Phospholipase A2. (818 aa) | ||||
RAP1A | RAP1A, member of RAS oncogene family. (184 aa) | ||||
PLA2G4F | Phospholipase A2. (850 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
MRAS | Muscle RAS oncogene homolog. (208 aa) | ||||
SRF | Serum response factor. (508 aa) | ||||
TRADD | TNFRSF1A associated via death domain. (311 aa) | ||||
FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) | ||||
VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) | ||||
NTF4 | Neurotrophin 4; Belongs to the NGF-beta family. (210 aa) | ||||
KRAS | KRAS proto-oncogene, GTPase. (189 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) | ||||
DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) | ||||
MAP3K11 | Mitogen-activated protein kinase kinase kinase. (847 aa) | ||||
FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) | ||||
CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (271 aa) | ||||
CACNG8 | Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (424 aa) | ||||
RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1642 aa) | ||||
MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa) | ||||
MAPKAPK3 | MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa) | ||||
ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) | ||||
CACNA2D3 | Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (958 aa) | ||||
FLNB | Filamin B. (2585 aa) | ||||
EPHA2 | EPH receptor A2. (976 aa) | ||||
EREG | Epiregulin. (169 aa) | ||||
CACNA1F | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1967 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa) | ||||
FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (267 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) | ||||
MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (365 aa) | ||||
GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) | ||||
CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) | ||||
RPS6KA1 | Ribosomal protein S6 kinase. (744 aa) | ||||
VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) | ||||
MAP3K6 | Mitogen-activated protein kinase kinase kinase 6. (1254 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) | ||||
RPS6KA3 | Ribosomal protein S6 kinase. (732 aa) | ||||
TGFA | Transforming growth factor alpha. (166 aa) | ||||
CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (949 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) | ||||
FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) | ||||
MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1592 aa) | ||||
RASGRP1 | RAS guanyl releasing protein 1. (785 aa) | ||||
CACNG3 | Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) | ||||
FAS | Fas cell surface death receptor. (335 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (835 aa) | ||||
ECSIT | ECSIT_Cterm domain-containing protein. (416 aa) | ||||
FGFR4 | Fibroblast growth factor receptor. (787 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (745 aa) | ||||
RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2. (1232 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (414 aa) | ||||
FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
DUSP9 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
INS-IGF2 | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (203 aa) | ||||
RASA1 | RAS p21 protein activator 1. (1047 aa) | ||||
LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa) | ||||
PPM1A | Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
FLNA | Filamin A. (2626 aa) | ||||
IKBKG | NEMO domain-containing protein. (173 aa) | ||||
ELK4 | ETS transcription factor ELK4. (431 aa) | ||||
CACNG2 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa) | ||||
CACNA2D1 | Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1071 aa) | ||||
FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa) | ||||
ANGPT2 | Angiopoietin 2. (496 aa) | ||||
NFKB2 | Nuclear factor kappa B subunit 2. (900 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (233 aa) | ||||
TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) | ||||
ATF4 | BZIP domain-containing protein. (351 aa) | ||||
FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa) | ||||
TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) | ||||
PPP3CC | Serine/threonine-protein phosphatase. (520 aa) | ||||
TEK | TEK receptor tyrosine kinase. (1124 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa) | ||||
MAP4K3 | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) | ||||
DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa) | ||||
PPM1B | PPM-type phosphatase domain-containing protein. (387 aa) | ||||
RASGRP4 | RAS guanyl releasing protein 4. (673 aa) | ||||
FGFR2 | Fibroblast growth factor receptor. (820 aa) | ||||
ARRB1 | Arrestin beta 1. (418 aa) | ||||
MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (467 aa) | ||||
DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) | ||||
ARRB2 | Arrestin beta 2. (430 aa) | ||||
RRAS2 | RAS related 2. (204 aa) | ||||
NR4A1 | Nuclear receptor subfamily 4 group A member 1. (589 aa) | ||||
BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa) | ||||
CACNB3 | Calcium voltage-gated channel auxiliary subunit beta 3. (444 aa) | ||||
IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) | ||||
PLA2G4A | Phospholipase A2. (749 aa) | ||||
PTPN7 | Protein tyrosine phosphatase non-receptor type 7. (465 aa) | ||||
HSPA6 | Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (643 aa) | ||||
RASA2 | RAS p21 protein activator 2. (849 aa) | ||||
MAP3K2 | Mitogen-activated protein kinase kinase kinase 2. (622 aa) | ||||
IL1R1 | Interleukin 1 receptor type 1. (569 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa) | ||||
RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (321 aa) | ||||
MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa) | ||||
MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (800 aa) | ||||
EFNA3 | Ephrin A3; Belongs to the ephrin family. (238 aa) | ||||
PDGFD | Platelet derived growth factor D. (370 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (743 aa) | ||||
FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) | ||||
HSPB1 | Uncharacterized protein. (37 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (550 aa) | ||||
EFNA1 | Ephrin A1; Belongs to the ephrin family. (204 aa) | ||||
MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa) | ||||
STK3 | Serine/threonine kinase 3. (519 aa) | ||||
PPP3R1 | Uncharacterized protein. (189 aa) | ||||
PPP3CB | Serine/threonine-protein phosphatase. (408 aa) | ||||
MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa) | ||||
GNA12 | G protein subunit alpha 12. (381 aa) | ||||
RPS6KA5 | Ribosomal protein S6 kinase. (797 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) | ||||
STK4 | Serine/threonine kinase 4. (490 aa) | ||||
PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
NGF | NGF domain-containing protein; Belongs to the NGF-beta family. (123 aa) | ||||
CACNB4 | Calcium voltage-gated channel auxiliary subunit beta 4. (502 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) | ||||
IGF2 | IlGF domain-containing protein. (180 aa) | ||||
RASGRP3 | RAS guanyl releasing protein 3. (690 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (382 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (521 aa) | ||||
MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (939 aa) | ||||
PGF | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (225 aa) | ||||
ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) | ||||
MAPK8IP2 | PID domain-containing protein. (178 aa) | ||||
CACNG4 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1206 aa) | ||||
MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
RASGRP2 | RAS guanyl releasing protein 2. (610 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (287 aa) | ||||
MECOM | MDS1 and EVI1 complex locus. (1230 aa) | ||||
EFNA2 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (195 aa) | ||||
CACNA2D2 | Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1119 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (545 aa) | ||||
GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) | ||||
NFATC1 | Nuclear factor of activated T cells 1. (968 aa) | ||||
FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) | ||||
PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) | ||||
AREG | EGF-like domain-containing protein. (274 aa) | ||||
NF1 | Neurofibromin 1. (2839 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
CACNA2D4 | VWFA domain-containing protein. (587 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
CDC42 | Cell division cycle 42. (191 aa) | ||||
ANGPT1 | Angiopoietin 1. (498 aa) | ||||
TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa) | ||||
EFNA4 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (201 aa) | ||||
RAC2 | Rac family small GTPase 2. (192 aa) | ||||
TAOK2 | TAO kinase 2. (1246 aa) | ||||
CACNB2 | GuKc domain-containing protein. (586 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa) | ||||
DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) | ||||
CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2116 aa) | ||||
DUSP5 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) | ||||
HSPA8 | Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa) | ||||
IGF1 | IlGF domain-containing protein. (196 aa) | ||||
NFATC3 | Nuclear factor of activated T cells 3. (1045 aa) | ||||
TAOK1 | TAO kinase 1. (1002 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
PTPRR | Protein tyrosine phosphatase receptor type R. (657 aa) | ||||
STMN1 | Stathmin; Belongs to the stathmin family. (172 aa) | ||||
NTRK1 | Tyrosine-protein kinase receptor. (787 aa) | ||||
ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1343 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
DUSP10 | Dual specificity phosphatase 10. (482 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1347 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1247 aa) |