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| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa) |
| | KSR2 | Kinase suppressor of ras 2. (950 aa) |
| | FLT3 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | RASSF5 | Ras association domain family member 5. (418 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
| | RALB | RAS like proto-oncogene B. (212 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | ZAP70 | Tyrosine-protein kinase. (704 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | FLT4 | Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1363 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (681 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa) |
| | RALA | RAS like proto-oncogene A. (206 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (268 aa) |
| | RAB5A | RAB5A, member RAS oncogene family. (215 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1561 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1335 aa) |
| | PLA2G4E | Phospholipase A2. (867 aa) |
| | PLA2G4D | Phospholipase A2. (818 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PLA2G4F | Phospholipase A2. (850 aa) |
| | MRAS | Muscle RAS oncogene homolog. (208 aa) |
| | PLA2G3 | Phospholipase A2 group III. (509 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | PLAAT2 | Phospholipase A and acyltransferase 2. (162 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | ETS2 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | NTF4 | Neurotrophin 4; Belongs to the NGF-beta family. (210 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | GAB1 | GRB2 associated binding protein 1. (724 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | PIK3R2 | Uncharacterized protein. (727 aa) |
| | RIN1 | Ras and Rab interactor 1. (782 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | RALBP1 | RalA binding protein 1. (655 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | EPHA2 | EPH receptor A2. (976 aa) |
| | PLA2G2E | Phospholipase A(2). (142 aa) |
| | PLA2G2A | Phospholipase A(2). (144 aa) |
| | PLA2G5 | Phospholipase A(2). (138 aa) |
| | PLA2G2D | Phospholipase A(2). (144 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (267 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | BCL2L1 | BCL2 like 1. (217 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | CSF1R | Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (949 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | RAB5C | RAB5C, member RAS oncogene family. (249 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (785 aa) |
| | SHC1 | SHC adaptor protein 1. (542 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (835 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (787 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (745 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2303 aa) |
| | RALGDS | Uncharacterized protein. (916 aa) |
| | RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2. (1232 aa) |
| | CALML4 | Calmodulin like 4. (196 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | INS-IGF2 | INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (203 aa) |
| | RASA1 | RAS p21 protein activator 1. (1047 aa) |
| | IKBKG | NEMO domain-containing protein. (173 aa) |
| | PAK5 | Non-specific serine/threonine protein kinase. (719 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (595 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa) |
| | ANGPT2 | Angiopoietin 2. (496 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (233 aa) |
| | FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | ABL2 | Tyrosine-protein kinase. (1182 aa) |
| | SHOC2 | SHOC2 leucine rich repeat scaffold protein. (582 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | TEK | TEK receptor tyrosine kinase. (1124 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa) |
| | PLA2G12B | Phospholipase A2 group XIIB. (195 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa) |
| | GAB2 | GRB2 associated binding protein 2. (651 aa) |
| | RAPGEF5 | Rap guanine nucleotide exchange factor 5. (730 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa) |
| | RASGRP4 | RAS guanyl releasing protein 4. (673 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (820 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | PLD2 | Phospholipase. (933 aa) |
| | RRAS2 | RAS related 2. (204 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (329 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | RASA2 | RAS p21 protein activator 2. (849 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa) |
| | EFNA3 | Ephrin A3; Belongs to the ephrin family. (238 aa) |
| | PDGFD | Platelet derived growth factor D. (370 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (743 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (116 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (204 aa) |
| | HTR7 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (325 aa) |
| | RASAL2 | RAS protein activator like 2. (1280 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | STK4 | Serine/threonine kinase 4. (490 aa) |
| | LOC100586578 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | PLAAT3 | Phospholipase A and acyltransferase 3. (170 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | NGF | NGF domain-containing protein; Belongs to the NGF-beta family. (123 aa) |
| | CALM1 | Calmodulin 1; Belongs to the calmodulin family. (150 aa) |
| | IGF2 | IlGF domain-containing protein. (180 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa) |
| | RASGRP3 | RAS guanyl releasing protein 3. (690 aa) |
| | GNB5 | G protein subunit beta 5. (357 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (382 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (716 aa) |
| | ARF6 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | PGF | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (225 aa) |
| | LOC100605369 | Uncharacterized protein. (571 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1206 aa) |
| | SHC3 | SHC adaptor protein 3. (598 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | RASGRP2 | RAS guanyl releasing protein 2. (610 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (287 aa) |
| | BAD | Uncharacterized protein. (82 aa) |
| | FOXO4 | Forkhead box O4. (505 aa) |
| | EFNA2 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (195 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (545 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | NF1 | Neurofibromin 1. (2839 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | CDC42 | Cell division cycle 42. (191 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | GRIN2A | Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa) |
| | EFNA4 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (201 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | PLD1 | Phospholipase. (1074 aa) |
| | PLA1A | Phospholipase A1 member A. (456 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa) |
| | IGF1 | IlGF domain-containing protein. (196 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (478 aa) |
| | PLA2G12A | Phospholipase A2 group XIIA. (189 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | RAB5B | Uncharacterized protein. (228 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (787 aa) |
| | RASSF1 | Ras association domain family member 1. (304 aa) |
