47 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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Your Input:
	SQSTM1	UBA_5 domain-containing protein. (197 aa)
	FUNDC1	FUN14 domain containing 1. (155 aa)
	EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3. (1120 aa)
	MRAS	Muscle RAS oncogene homolog. (208 aa)
	TFEB	Transcription factor EB. (487 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	TBC1D17	TBC1 domain family member 17. (648 aa)
	MFN1	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (658 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1117 aa)
	TFE3	Transcription factor binding to IGHM enhancer 3. (575 aa)
	RHOT2	Miro domain-containing protein. (187 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	ULK1	Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
	PGAM5	PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (258 aa)
	ATG9A	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (863 aa)
	CSNK2A1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
	BCL2L1	BCL2 like 1. (217 aa)
	E2F1	E2F transcription factor 1. (391 aa)
	BECN1	Beclin 1. (450 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	AMBRA1	Autophagy and beclin 1 regulator 1. (1284 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (278 aa)
	ATF4	BZIP domain-containing protein. (351 aa)
	BNIP3L	BCL2 interacting protein 3 like. (219 aa)
	TBK1	TANK binding kinase 1. (729 aa)
	USP15	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
	SP1	Sp1 transcription factor. (786 aa)
	RRAS2	RAS related 2. (204 aa)
	RPS27A-2	Ubiquitin-like domain-containing protein. (156 aa)
	TBC1D15	TBC1 domain family member 15. (694 aa)
	FOXO3	Forkhead box O3. (672 aa)
	TAX1BP1	Tax1 binding protein 1. (813 aa)
	RAB7A	RAB7A, member RAS oncogene family. (207 aa)
	MAPK10	Mitogen-activated protein kinase. (550 aa)
	MAPK9	Mitogen-activated protein kinase. (382 aa)
	BNIP3	Uncharacterized protein. (231 aa)
	GABARAPL1	GABA type A receptor associated protein like 1. (146 aa)
	GABARAP	GABA type A receptor-associated protein. (117 aa)
	GABARAPL2	GABA type A receptor associated protein like 2. (117 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (551 aa)
	OPTN	Optineurin. (577 aa)
	FIS1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	NBR1	NBR1 autophagy cargo receptor. (968 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	MITF	Melanocyte inducing transcription factor. (526 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (850 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBRA1	ATG5	ENSNLEP00000017019	ENSNLEP00000016123	Autophagy and beclin 1 regulator 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.541
AMBRA1	BECN1	ENSNLEP00000017019	ENSNLEP00000014406	Autophagy and beclin 1 regulator 1.	Beclin 1.	0.999
AMBRA1	BNIP3L	ENSNLEP00000017019	ENSNLEP00000019692	Autophagy and beclin 1 regulator 1.	BCL2 interacting protein 3 like.	0.459
AMBRA1	FUNDC1	ENSNLEP00000017019	ENSNLEP00000003053	Autophagy and beclin 1 regulator 1.	FUN14 domain containing 1.	0.449
AMBRA1	GABARAP	ENSNLEP00000017019	ENSNLEP00000033461	Autophagy and beclin 1 regulator 1.	GABA type A receptor-associated protein.	0.601
AMBRA1	GABARAPL1	ENSNLEP00000017019	ENSNLEP00000032713	Autophagy and beclin 1 regulator 1.	GABA type A receptor associated protein like 1.	0.506
AMBRA1	GABARAPL2	ENSNLEP00000017019	ENSNLEP00000036021	Autophagy and beclin 1 regulator 1.	GABA type A receptor associated protein like 2.	0.500
AMBRA1	NBR1	ENSNLEP00000017019	ENSNLEP00000045785	Autophagy and beclin 1 regulator 1.	NBR1 autophagy cargo receptor.	0.461
AMBRA1	OPTN	ENSNLEP00000017019	ENSNLEP00000038794	Autophagy and beclin 1 regulator 1.	Optineurin.	0.450
AMBRA1	SQSTM1	ENSNLEP00000017019	ENSNLEP00000002152	Autophagy and beclin 1 regulator 1.	UBA_5 domain-containing protein.	0.522
AMBRA1	ULK1	ENSNLEP00000017019	ENSNLEP00000010351	Autophagy and beclin 1 regulator 1.	Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.	0.987
ATF4	EIF2AK3	ENSNLEP00000018522	ENSNLEP00000003807	BZIP domain-containing protein.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.964
ATG5	AMBRA1	ENSNLEP00000016123	ENSNLEP00000017019	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy and beclin 1 regulator 1.	0.541
ATG5	ATG9A	ENSNLEP00000016123	ENSNLEP00000011201	Autophagy protein 5; Involved in autophagic vesicle formation.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.499
ATG5	BCL2L1	ENSNLEP00000016123	ENSNLEP00000011718	Autophagy protein 5; Involved in autophagic vesicle formation.	BCL2 like 1.	0.834
ATG5	BECN1	ENSNLEP00000016123	ENSNLEP00000014406	Autophagy protein 5; Involved in autophagic vesicle formation.	Beclin 1.	0.904
ATG5	BNIP3L	ENSNLEP00000016123	ENSNLEP00000019692	Autophagy protein 5; Involved in autophagic vesicle formation.	BCL2 interacting protein 3 like.	0.461
ATG5	FUNDC1	ENSNLEP00000016123	ENSNLEP00000003053	Autophagy protein 5; Involved in autophagic vesicle formation.	FUN14 domain containing 1.	0.597
ATG5	GABARAP	ENSNLEP00000016123	ENSNLEP00000033461	Autophagy protein 5; Involved in autophagic vesicle formation.	GABA type A receptor-associated protein.	0.987
ATG5	GABARAPL1	ENSNLEP00000016123	ENSNLEP00000032713	Autophagy protein 5; Involved in autophagic vesicle formation.	GABA type A receptor associated protein like 1.	0.993

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