STRINGSTRING
ERP29 ERP29 MOGS MOGS EIF2S1 EIF2S1 UBXN2A UBXN2A HSPH1 HSPH1 YOD1 YOD1 EIF2AK1 EIF2AK1 MAP2K7 MAP2K7 CANX CANX TUSC3 TUSC3 HERPUD1 HERPUD1 BAG2 BAG2 EIF2AK3 EIF2AK3 UBXN6 UBXN6 UBE2D4 UBE2D4 CUL1 CUL1 NGLY1 NGLY1 SEC23A SEC23A UBXN1 UBXN1 STT3B STT3B RNF185 RNF185 SEC13 SEC13 BAX BAX VCP VCP SEC62 SEC62 DERL1 DERL1 MAN1A2 MAN1A2 DNAJA1 DNAJA1 PDIA3 PDIA3 SYVN1 SYVN1 RPN2 RPN2 DNAJC10 DNAJC10 HSP90B1 HSP90B1 DNAJB11 DNAJB11 ATF6B ATF6B STT3A STT3A SKP1 SKP1 SAR1B SAR1B SEC24A SEC24A LMAN1 LMAN1 TRAF2 TRAF2 UBXN4 UBXN4 MAN1B1 MAN1B1 SEC24D SEC24D ERLEC1 ERLEC1 MAN1C1 MAN1C1 DERL2 DERL2 SEC23B SEC23B MBTPS2 MBTPS2 EDEM2 EDEM2 DNAJC5B DNAJC5B MBTPS1 MBTPS1 SAR1A SAR1A TXNDC5 TXNDC5 WFS1 WFS1 UBE2D1 UBE2D1 SEC61A2 SEC61A2 ERO1A ERO1A LMAN2 LMAN2 DNAJC1 DNAJC1 CALR CALR BCAP31 BCAP31 SEC63 SEC63 SSR4 SSR4 MAN1A1 MAN1A1 RPN1 RPN1 ATF6 ATF6 DAD1 DAD1 CRYAA CRYAA SEC31B SEC31B ERN1 ERN1 ATF4 ATF4 DNAJA2 DNAJA2 UGGT1 UGGT1 PLAA PLAA SEC24B SEC24B SEC24C SEC24C SEL1L SEL1L SEC61B SEC61B DDIT3 DDIT3 RAD23B RAD23B HSPA5 HSPA5 UBQLN3 UBQLN3 UBQLN2 UBQLN2 HSPA6 HSPA6 UBE2G2 UBE2G2 ERO1B ERO1B SSR1 SSR1 UBE2J1 UBE2J1 SEC61A1 SEC61A1 GANAB GANAB HSP90AA1 HSP90AA1 UBE2G1 UBE2G1 MAPK10 MAPK10 UBQLN1 UBQLN1 EDEM3 EDEM3 OS9 OS9 SEC61G SEC61G PDIA6 PDIA6 CRYAB CRYAB MAPK9 MAPK9 AMFR AMFR UBE2D2 UBE2D2 DNAJC5 DNAJC5 BAK1 BAK1 P4HB P4HB RBX1 RBX1 EIF2AK4 EIF2AK4 BCL2 BCL2 DNAJC3 DNAJC3 DERL3 DERL3 NPLOC4 NPLOC4 SVIP SVIP RNF5 RNF5 HYOU1 HYOU1 TRAM1 TRAM1 NSFL1C NSFL1C HSPA4L HSPA4L NFE2L2 NFE2L2 UFD1 UFD1 XBP1 XBP1 DDOST DDOST UBXN8 UBXN8 SELENOS SELENOS HSPA8 HSPA8 SSR2 SSR2 MAPK8 MAPK8 MARCHF6 MARCHF6 BAG1 BAG1 LOC100603153 LOC100603153 MAP3K5 MAP3K5
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERP29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (261 aa)
MOGSMannosyl-oligosaccharide glucosidase. (820 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
UBXN2AUBX domain protein 2A. (259 aa)
HSPH1Heat shock protein family H (Hsp110) member 1. (836 aa)
YOD1YOD1 deubiquitinase. (348 aa)
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (614 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (391 aa)
CANXCalnexin. (592 aa)
TUSC3Tumor suppressor candidate 3. (348 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1120 aa)
UBXN6UBX domain protein 6. (441 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
NGLY1N-glycanase 1. (654 aa)
SEC23AProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
UBXN1UBX domain protein 1. (288 aa)
STT3BSTT3 oligosaccharyltransferase complex catalytic subunit B. (820 aa)
RNF185Ring finger protein 185. (192 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
BAXUncharacterized protein. (194 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (808 aa)
SEC62SEC62 homolog, preprotein translocation factor. (399 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
MAN1A2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (634 aa)
DNAJA1Uncharacterized protein. (397 aa)
PDIA3Protein disulfide-isomerase. (505 aa)
SYVN1Synoviolin 1. (617 aa)
RPN2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (631 aa)
DNAJC10DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. (793 aa)
HSP90B1Heat shock protein 90 beta family member 1. (804 aa)
DNAJB11J domain-containing protein. (358 aa)
ATF6BActivating transcription factor 6 beta. (718 aa)
STT3ASTT3 oligosaccharyltransferase complex catalytic subunit A. (705 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
SAR1BSecretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
SEC24ASEC24 homolog A, COPII coat complex component. (1093 aa)
LMAN1Lectin, mannose binding 1. (510 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
UBXN4UBX domain protein 4. (508 aa)
MAN1B1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (698 aa)
SEC24DSEC24 homolog D, COPII coat complex component. (1032 aa)
ERLEC1Endoplasmic reticulum lectin 1. (483 aa)
MAN1C1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (618 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
SEC23BProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (502 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (577 aa)
DNAJC5BDnaJ heat shock protein family (Hsp40) member C5 beta. (199 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
TXNDC5Thioredoxin domain containing 5. (431 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
SEC61A2SEC61 translocon alpha 2 subunit. (476 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
LMAN2Lectin, mannose binding 2. (354 aa)
DNAJC1DnaJ heat shock protein family (Hsp40) member C1. (542 aa)
CALRCalreticulin. (417 aa)
BCAP31Uncharacterized protein. (246 aa)
SEC63SEC63 homolog, protein translocation regulator. (760 aa)
SSR4Signal sequence receptor subunit 4. (173 aa)
MAN1A1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (649 aa)
RPN1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (607 aa)
ATF6Activating transcription factor 6. (657 aa)
DAD1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
CRYAASHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (173 aa)
SEC31BSEC31 homolog B, COPII coat complex component. (1146 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
ATF4BZIP domain-containing protein. (351 aa)
DNAJA2DnaJ heat shock protein family (Hsp40) member A2. (412 aa)
UGGT1UDP-glucose glycoprotein glucosyltransferase 1. (1556 aa)
PLAAPhospholipase A2 activating protein. (764 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1236 aa)
SEC24CUncharacterized protein. (1071 aa)
SEL1LSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (794 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
UBQLN3Ubiquilin 3. (655 aa)
UBQLN2Ubiquilin 2. (624 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (643 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
ERO1BEndoplasmic reticulum oxidoreductase 1 beta. (467 aa)
SSR1Signal sequence receptor subunit 1. (298 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (318 aa)
SEC61A1SEC61 translocon alpha 1 subunit. (482 aa)
GANABGlucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. (966 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (853 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
UBQLN1Ubiquilin 1. (589 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (948 aa)
OS9OS9 endoplasmic reticulum lectin. (667 aa)
SEC61GSEC61 translocon gamma subunit. (68 aa)
PDIA6Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (482 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
MAPK9Mitogen-activated protein kinase. (382 aa)
AMFRAutocrine motility factor receptor. (636 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
BAK1BCL2 antagonist/killer 1. (182 aa)
P4HBProtein disulfide-isomerase. (518 aa)
RBX1Ring-box 1. (108 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1642 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (238 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (607 aa)
SVIPSmall VCP interacting protein. (77 aa)
RNF5Ring finger protein 5. (180 aa)
HYOU1Hypoxia up-regulated 1. (956 aa)
TRAM1Translocation associated membrane protein 1. (336 aa)
NSFL1CNSFL1 cofactor. (337 aa)
HSPA4LHeat shock protein family A (Hsp70) member 4 like. (839 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (607 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (312 aa)
XBP1BZIP domain-containing protein. (376 aa)
DDOSTDolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (456 aa)
UBXN8UBX domain protein 8. (284 aa)
SELENOSUncharacterized protein. (218 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
SSR2Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. (183 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
MARCHF6Membrane associated ring-CH-type finger 6. (937 aa)
BAG1BCL2 associated athanogene 1. (328 aa)
LOC100603153Uncharacterized protein. (445 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1347 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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