42 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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Your Input:
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
	MAPK12	Mitogen-activated protein kinase. (368 aa)
	MAPKAPK2	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (370 aa)
	SPHK1	DAGKc domain-containing protein. (398 aa)
	PLA2G4E	Phospholipase A2. (867 aa)
	PLA2G4D	Phospholipase A2. (818 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
	PLA2G4F	Phospholipase A2. (850 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	PIK3R2	Uncharacterized protein. (727 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (426 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	SH2D2A	SH2 domain containing 2A. (399 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (520 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (604 aa)
	PLA2G4A	Phospholipase A2. (749 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
	MAPK14	Mitogen-activated protein kinase. (321 aa)
	HSPB1	Uncharacterized protein. (37 aa)
	PPP3R1	Uncharacterized protein. (189 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (408 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
	SPHK2	Sphingosine kinase 2. (630 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
	NFATC2	Nuclear factor of activated T cells 2. (905 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	BAD	Uncharacterized protein. (82 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	CDC42	Cell division cycle 42. (191 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
	PIK3R3	Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
	PXN	Uncharacterized protein. (1078 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT3	ENSNLEP00000028045	ENSNLEP00000023896	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.950
AKT1	BAD	ENSNLEP00000028045	ENSNLEP00000038361	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.996
AKT1	CASP9	ENSNLEP00000028045	ENSNLEP00000009264	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caspase 9; Belongs to the peptidase C14A family.	0.987
AKT1	CDC42	ENSNLEP00000028045	ENSNLEP00000040816	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cell division cycle 42.	0.961
AKT1	HRAS	ENSNLEP00000028045	ENSNLEP00000010109	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HRas proto-oncogene, GTPase.	0.753
AKT1	KDR	ENSNLEP00000028045	ENSNLEP00000044105	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.557
AKT1	KRAS	ENSNLEP00000028045	ENSNLEP00000006371	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	KRAS proto-oncogene, GTPase.	0.759
AKT1	MAP2K1	ENSNLEP00000028045	ENSNLEP00000036059	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.423
AKT1	MAPK1	ENSNLEP00000028045	ENSNLEP00000027273	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.975
AKT1	MAPK12	ENSNLEP00000028045	ENSNLEP00000000724	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.934
AKT1	MAPK13	ENSNLEP00000028045	ENSNLEP00000010961	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.935
AKT1	MAPK14	ENSNLEP00000028045	ENSNLEP00000024518	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.983
AKT1	MAPKAPK2	ENSNLEP00000028045	ENSNLEP00000000896	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily.	0.837
AKT1	NOS3	ENSNLEP00000028045	ENSNLEP00000004866	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase; Produces nitric oxide (NO).	0.994
AKT1	NRAS	ENSNLEP00000028045	ENSNLEP00000040445	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NRAS proto-oncogene, GTPase.	0.680
AKT1	PIK3CA	ENSNLEP00000028045	ENSNLEP00000006936	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.993
AKT1	PIK3CB	ENSNLEP00000028045	ENSNLEP00000005291	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.981
AKT1	PIK3R1	ENSNLEP00000028045	ENSNLEP00000031935	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 1.	0.983
AKT1	PIK3R2	ENSNLEP00000028045	ENSNLEP00000007175	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.966
AKT1	PIK3R3	ENSNLEP00000028045	ENSNLEP00000045443	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 3.	0.963

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