STRINGSTRING
ITGA2B ITGA2B SYK SYK MAPK12 MAPK12 ADCY3 ADCY3 LYN LYN TBXA2R TBXA2R PTGIR PTGIR GNAQ GNAQ ARHGAP35 ARHGAP35 VWF VWF P2RY12 P2RY12 ITPR1 ITPR1 LOC100600502 LOC100600502 PLA2G4E PLA2G4E PLA2G4D PLA2G4D NOS3 NOS3 RAP1A RAP1A PLA2G4F PLA2G4F PIK3CB PIK3CB PLCB3 PLCB3 PIK3CA PIK3CA PIK3R2 PIK3R2 FGB FGB FGA FGA GUCY1A1 GUCY1A1 PPP1CA PPP1CA COL3A1 COL3A1 RHOA RHOA MYL12A MYL12A GNAI2 GNAI2 GUCY1A2 GUCY1A2 PRKG2 PRKG2 PIK3CG PIK3CG MAPK13 MAPK13 COL1A1 COL1A1 GNAI1 GNAI1 MYLK2 MYLK2 PIK3R5 PIK3R5 GP6 GP6 MYLK4 MYLK4 RASGRP1 RASGRP1 ADCY2 ADCY2 PRKG1 PRKG1 TLN2 TLN2 F2R F2R PLCB1 PLCB1 PLCB4 PLCB4 FCGR2A FCGR2A GNA13 GNA13 PPP1CB PPP1CB COL1A2 COL1A2 APBB1IP APBB1IP P2RX1 P2RX1 PLA2G4A PLA2G4A LOC101176289 LOC101176289 P2RY1 P2RY1 ACTG1 ACTG1 PRKCI PRKCI AKT3 AKT3 MAPK14 MAPK14 FCER1G FCER1G GP1BB GP1BB MAPK1 MAPK1 GUCY1B1 GUCY1B1 AKT1 AKT1 PRKACB PRKACB ITGB1 ITGB1 PIK3R1 PIK3R1 ITGB3 ITGB3 PPP1R12A PPP1R12A MYL12B MYL12B TLN1 TLN1 ITPR2 ITPR2 SNAP23 SNAP23 ROCK2 ROCK2 RASGRP2 RASGRP2 ADCY8 ADCY8 FYN FYN VAMP8 VAMP8 GNAI3 GNAI3 ARHGEF12 ARHGEF12 ITGA2 ITGA2 ROCK1 ROCK1 PIK3R3 PIK3R3 ADCY1 ADCY1 LCP2 LCP2 ADCY5 ADCY5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1040 aa)
SYKTyrosine-protein kinase. (532 aa)
MAPK12Mitogen-activated protein kinase. (368 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
LYNTyrosine-protein kinase. (512 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
PTGIRProstaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (386 aa)
GNAQG protein subunit alpha q. (358 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
VWFVon Willebrand factor. (2790 aa)
P2RY12Purinergic receptor P2Y12. (342 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
LOC100600502Guanylate cyclase domain-containing protein. (613 aa)
PLA2G4EPhospholipase A2. (867 aa)
PLA2G4DPhospholipase A2. (818 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PLA2G4FPhospholipase A2. (850 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
PIK3R2Uncharacterized protein. (727 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (863 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
RHOARas homolog family member A. (193 aa)
MYL12AMyosin light chain 12A. (177 aa)
GNAI2G protein subunit alpha i2. (355 aa)
GUCY1A2Uncharacterized protein. (385 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
COL1A1Collagen type I alpha 1 chain. (1386 aa)
GNAI1G protein subunit alpha i1. (353 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (889 aa)
GP6Ig-like domain-containing protein. (222 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (388 aa)
RASGRP1RAS guanyl releasing protein 1. (785 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (966 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
TLN2Uncharacterized protein. (2289 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
FCGR2AFc fragment of IgG receptor IIa. (317 aa)
GNA13G protein subunit alpha 13. (373 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (667 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (379 aa)
PLA2G4APhospholipase A2. (749 aa)
LOC101176289Uncharacterized protein. (244 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
ACTG1Actin gamma 1. (378 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
FCER1GUncharacterized protein. (112 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (206 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (643 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (806 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
MYL12BMyosin light chain 12B. (172 aa)
TLN1Talin 1. (2542 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
RASGRP2RAS guanyl releasing protein 2. (610 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
FYNTyrosine-protein kinase. (537 aa)
VAMP8V-SNARE coiled-coil homology domain-containing protein. (116 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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