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| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1072 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (719 aa) |
| | CASR | Calcium sensing receptor. (1088 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (368 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | CYBB | Cytochrome b-245 beta chain. (570 aa) |
| | TANK | TRAF family member associated NFKB activator. (425 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa) |
| | ERBIN | Erbb2 interacting protein. (1418 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1020 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1970 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa) |
| | MFN1 | Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (658 aa) |
| | TXNIP | Thioredoxin interacting protein. (391 aa) |
| | NLRP12 | NLR family pyrin domain containing 12. (1062 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (1866 aa) |
| | CAMP | Cathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity; Belongs to the cathelicidin family. (173 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | PANX1 | Pannexin; Structural component of the gap junctions and the hemichannels. (425 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (603 aa) |
| | CASP4 | Caspase 4; Belongs to the peptidase C14A family. (377 aa) |
| | CASP5 | Caspase 5; Belongs to the peptidase C14A family. (448 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | CXCL3 | C-X-C motif chemokine. (107 aa) |
| | CXCL2 | C-X-C motif chemokine. (106 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (282 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (536 aa) |
| | IRF7 | Interferon regulatory factor 7. (524 aa) |
| | ANTXR2 | Anthrax toxin receptor; Belongs to the ATR family. (488 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | NAMPT | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (475 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | DHX33 | Helicase C-terminal domain-containing protein. (404 aa) |
| | NLRP1 | NLR family pyrin domain containing 1. (1470 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (509 aa) |
| | BCL2L1 | BCL2 like 1. (217 aa) |
| | MEFV | MEFV innate immuity regulator, pyrin. (781 aa) |
| | ANTXR1 | ANTXR cell adhesion molecule 1. (564 aa) |
| | PKN2 | Uncharacterized protein. (984 aa) |
| | GBP3 | Guanylate binding protein 3. (563 aa) |
| | GBP1 | Guanylate binding protein 1. (590 aa) |
| | GBP4 | Guanylate binding protein 4. (640 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | SHARPIN | SHANK associated RH domain interactor. (340 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | TYK2 | Tyrosine-protein kinase. (1181 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (745 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | IFI16 | Interferon gamma inducible protein 16. (723 aa) |
| | AIM2 | Absent in melanoma 2. (344 aa) |
| | GPRC6A | ANF_receptor domain-containing protein. (461 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (691 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | IKBKG | NEMO domain-containing protein. (173 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa) |
| | TRPV2 | Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (790 aa) |
| | DEFA6 | Defensin alpha 6. (100 aa) |
| | DEFA4 | Defensin alpha 4. (97 aa) |
| | LOC100595156 | DEFENSIN domain-containing protein. (99 aa) |
| | DEFA5 | Defensin alpha 5. (94 aa) |
| | XIAP | X-linked inhibitor of apoptosis. (497 aa) |
| | LOC100604016 | DEFSN domain-containing protein. (64 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | JAK1 | Tyrosine-protein kinase. (1149 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | RNF31 | Uncharacterized protein. (1072 aa) |
| | IRF9 | Interferon regulatory factor 9. (392 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (506 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | MCU | Mitochondrial calcium uniporter. (352 aa) |
| | CARD6 | Caspase recruitment domain family member 6. (1038 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | RNASEL | Ribonuclease L. (741 aa) |
| | NEK7 | NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa) |
| | G1SBE5_NOMLE | Uncharacterized protein. (198 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (321 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (743 aa) |
| | HSP90AA1 | Heat shock protein 90 alpha family class A member 1. (853 aa) |
| | STAT2 | Signal transducer and activator of transcription. (852 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | LOC100595932 | Uncharacterized protein. (198 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa) |
| | IFNA8 | Interferon alpha 8. (189 aa) |
| | ATG16L1 | Autophagy related 16 like 1. (600 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (382 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (187 aa) |
| | GABARAPL1 | GABA type A receptor associated protein like 1. (146 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa) |
| | LOC100595437 | Thioredoxin domain-containing protein. (105 aa) |
| | GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (699 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | ENSNLEP00000037515 | Thioredoxin; Belongs to the thioredoxin family. (105 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (400 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (615 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (297 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (557 aa) |
| | ENSNLEP00000042279 | Uncharacterized protein. (587 aa) |
| | IFNA5 | Interferon alpha 5. (189 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | CARD8 | FIIND domain-containing protein. (406 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (404 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | IL6 | Uncharacterized protein. (258 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | ENSNLEP00000048177 | Defensin_propep domain-containing protein. (94 aa) |
| | LOC100595279 | Uncharacterized protein. (212 aa) |
