50 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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Your Input:
	SYK	Tyrosine-protein kinase. (532 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	NFKBIE	NFKB inhibitor epsilon. (487 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (627 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	PIK3R2	Uncharacterized protein. (727 aa)
	LILRA4	Leukocyte immunoglobulin like receptor A4. (499 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	MALT1	MALT1 paracaspase. (824 aa)
	CARD11	Caspase recruitment domain family member 11. (1154 aa)
	CD19	CD19 molecule. (558 aa)
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (969 aa)
	CD79A	CD79a molecule. (230 aa)
	PIK3AP1	Phosphoinositide-3-kinase adaptor protein 1. (805 aa)
	DAPP1	Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (248 aa)
	IKBKG	NEMO domain-containing protein. (173 aa)
	CD79B	CD79b molecule. (229 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (520 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (743 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
	PPP3R1	Uncharacterized protein. (189 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (408 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
	RASGRP3	RAS guanyl releasing protein 3. (690 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
	LILRB1	Uncharacterized protein. (493 aa)
	NFATC2	Nuclear factor of activated T cells 2. (905 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (551 aa)
	INPPL1	Inositol polyphosphate phosphatase like 1. (1256 aa)
	NFATC1	Nuclear factor of activated T cells 1. (968 aa)
	CD81	Tetraspanin. (274 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	BCL10	CARD domain-containing protein. (319 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	CD72	CD72 molecule. (365 aa)
	NFATC3	Nuclear factor of activated T cells 3. (1045 aa)
	PIK3R3	Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT3	ENSNLEP00000028045	ENSNLEP00000023896	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.950
AKT1	BCL10	ENSNLEP00000028045	ENSNLEP00000040652	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CARD domain-containing protein.	0.598
AKT1	CARD11	ENSNLEP00000028045	ENSNLEP00000012902	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caspase recruitment domain family member 11.	0.516
AKT1	CD19	ENSNLEP00000028045	ENSNLEP00000013846	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD19 molecule.	0.488
AKT1	CD81	ENSNLEP00000028045	ENSNLEP00000040088	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tetraspanin.	0.482
AKT1	CHUK	ENSNLEP00000028045	ENSNLEP00000025468	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.997
AKT1	DAPP1	ENSNLEP00000028045	ENSNLEP00000016650	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Dual adaptor of phosphotyrosine and 3-phosphoinositides 1.	0.419
AKT1	FOS	ENSNLEP00000028045	ENSNLEP00000047435	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Fos proto-oncogene, AP-1 transcription factor subunit.	0.572
AKT1	GRB2	ENSNLEP00000028045	ENSNLEP00000040743	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Growth factor receptor bound protein 2.	0.749
AKT1	GSK3B	ENSNLEP00000028045	ENSNLEP00000026237	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.996
AKT1	HRAS	ENSNLEP00000028045	ENSNLEP00000010109	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HRas proto-oncogene, GTPase.	0.753
AKT1	IKBKB	ENSNLEP00000028045	ENSNLEP00000015614	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.991
AKT1	IKBKG	ENSNLEP00000028045	ENSNLEP00000017384	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NEMO domain-containing protein.	0.958
AKT1	INPPL1	ENSNLEP00000028045	ENSNLEP00000037879	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Inositol polyphosphate phosphatase like 1.	0.711
AKT1	KRAS	ENSNLEP00000028045	ENSNLEP00000006371	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	KRAS proto-oncogene, GTPase.	0.759
AKT1	LYN	ENSNLEP00000028045	ENSNLEP00000001435	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.703
AKT1	MAP2K1	ENSNLEP00000028045	ENSNLEP00000036059	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.423
AKT1	MAPK1	ENSNLEP00000028045	ENSNLEP00000027273	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.975
AKT1	NFATC1	ENSNLEP00000028045	ENSNLEP00000039861	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nuclear factor of activated T cells 1.	0.484
AKT1	NFKB1	ENSNLEP00000028045	ENSNLEP00000016247	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nuclear factor kappa B subunit 1.	0.714

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