42 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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Your Input:
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (764 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (738 aa)
	GNAQ	G protein subunit alpha q. (358 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1335 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	GRIA2	Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	CREBBP	CREB binding protein. (2442 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (732 aa)
	CAMK4	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
	CALML4	Calmodulin like 4. (196 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
	ATF4	BZIP domain-containing protein. (351 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (520 aa)
	RAF1	Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
	PPP1R1A	Protein phosphatase 1 regulatory inhibitor subunit 1A. (156 aa)
	PPP3R1	Uncharacterized protein. (189 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (408 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
	CALML3	Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
	GRM1	Glutamate metabotropic receptor 1. (1195 aa)
	PRKACB	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
	CALM1	Calmodulin 1; Belongs to the calmodulin family. (150 aa)
	GRM5	Glutamate metabotropic receptor 5. (1210 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	ADCY1	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY8	ENSNLEP00000046695	ENSNLEP00000038876	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.945
ADCY1	CALM1	ENSNLEP00000046695	ENSNLEP00000029615	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin 1; Belongs to the calmodulin family.	0.923
ADCY1	CALML3	ENSNLEP00000046695	ENSNLEP00000027964	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin like 3; Belongs to the calmodulin family.	0.923
ADCY1	CALML4	ENSNLEP00000046695	ENSNLEP00000015963	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calmodulin like 4.	0.923
ADCY1	CAMK4	ENSNLEP00000046695	ENSNLEP00000013952	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily.	0.901
ADCY1	PRKACB	ENSNLEP00000046695	ENSNLEP00000029039	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.922
ADCY1	PRKCA	ENSNLEP00000046695	ENSNLEP00000000331	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.909
ADCY1	PRKCB	ENSNLEP00000046695	ENSNLEP00000043873	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.905
ADCY1	PRKCG	ENSNLEP00000046695	ENSNLEP00000007555	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.908
ADCY8	ADCY1	ENSNLEP00000038876	ENSNLEP00000046695	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.945
ADCY8	CALM1	ENSNLEP00000038876	ENSNLEP00000029615	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin 1; Belongs to the calmodulin family.	0.967
ADCY8	CALML3	ENSNLEP00000038876	ENSNLEP00000027964	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 3; Belongs to the calmodulin family.	0.977
ADCY8	CALML4	ENSNLEP00000038876	ENSNLEP00000015963	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin like 4.	0.970
ADCY8	CAMK4	ENSNLEP00000038876	ENSNLEP00000013952	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily.	0.950
ADCY8	GRIN2A	ENSNLEP00000038876	ENSNLEP00000041856	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Glutamate ionotropic receptor NMDA type subunit 2A.	0.664
ADCY8	GRIN2B	ENSNLEP00000038876	ENSNLEP00000004561	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Glutamate ionotropic receptor NMDA type subunit 2B.	0.594
ADCY8	PRKACB	ENSNLEP00000038876	ENSNLEP00000029039	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.953
ADCY8	PRKCA	ENSNLEP00000038876	ENSNLEP00000000331	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.955
ADCY8	PRKCB	ENSNLEP00000038876	ENSNLEP00000043873	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.916
ADCY8	PRKCG	ENSNLEP00000038876	ENSNLEP00000007555	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.914

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