STRINGSTRING
GNB1 GNB1 PRKCA PRKCA GNAO1 GNAO1 BRAF BRAF MAOB MAOB GNG8 GNG8 GNAQ GNAQ GNGT2 GNGT2 SLC6A4 SLC6A4 ITPR1 ITPR1 PLA2G4E PLA2G4E PLA2G4D PLA2G4D GNG3 GNG3 PLA2G4F PLA2G4F TPH2 TPH2 GABRB2 GABRB2 TRPC1 TRPC1 PLCB3 PLCB3 KRAS KRAS GNB4 GNB4 HTR3C HTR3C PRKCG PRKCG GNAI2 GNAI2 KCNJ5 KCNJ5 HTR6 HTR6 CACNA1F CACNA1F HRAS HRAS GNAI1 GNAI1 GNG5 GNG5 CASP3 CASP3 KCNJ3 KCNJ3 HTR1E HTR1E CYP2C19 CYP2C19 CYP2C8 CYP2C8 CYP4X1 CYP4X1 PLCB1 PLCB1 PLCB4 PLCB4 CYP2J2 CYP2J2 GNGT1 GNGT1 GNG11 GNG11 SLC18A2 SLC18A2 GABRB1 GABRB1 ALOX15 ALOX15 TPH1 TPH1 PTGS2 PTGS2 PLA2G4A PLA2G4A HTR1A HTR1A LOC101176289 LOC101176289 HTR1B HTR1B HTR1F HTR1F RAF1 RAF1 GNG13 GNG13 GNG4 GNG4 HTR3A HTR3A APP APP HTR7 HTR7 MAPK1 MAPK1 SLC18A1 SLC18A1 HTR5A HTR5A LOC100586578 LOC100586578 KCNN2 KCNN2 PRKACB PRKACB GNG2 GNG2 DDC DDC GNB5 GNB5 KCND2 KCND2 ITPR2 ITPR2 HTR2C HTR2C MAP2K1 MAP2K1 HTR2A HTR2A GNG12 GNG12 GNG7 GNG7 KCNJ9 KCNJ9 NRAS NRAS HTR3E HTR3E GNAI3 GNAI3 MAOA MAOA PRKCB PRKCB CACNA1D CACNA1D KCNJ6 KCNJ6 GABRB3 GABRB3 ADCY5 ADCY5 HTR2B HTR2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNB1G protein subunit beta 1. (340 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
GNAO1G protein subunit alpha o1. (353 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
MAOBAmine oxidase. (520 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNAQG protein subunit alpha q. (358 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (625 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
PLA2G4EPhospholipase A2. (867 aa)
PLA2G4DPhospholipase A2. (818 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLA2G4FPhospholipase A2. (850 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (881 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GNB4G protein subunit beta 4. (340 aa)
HTR3C5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (447 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GNAI2G protein subunit alpha i2. (355 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (418 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (389 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1967 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
GNAI1G protein subunit alpha i1. (353 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
CYP2C19Cytochrome P450 family 2 subfamily C member 19; Belongs to the cytochrome P450 family. (490 aa)
CYP2C8Cytochrome P450 family 2 subfamily C member 8; Belongs to the cytochrome P450 family. (420 aa)
CYP4X1Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (509 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
SLC18A2Solute carrier family 18 member A2. (514 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
ALOX15Arachidonate 15-lipoxygenase. (662 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
PLA2G4APhospholipase A2. (749 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
LOC101176289Uncharacterized protein. (244 aa)
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
HTR1F5-hydroxytryptamine receptor 1F. (366 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (116 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (501 aa)
APPAmyloid beta precursor protein. (757 aa)
HTR7G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (325 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
HTR5A5-hydroxytryptamine receptor 5A. (357 aa)
LOC100586578Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
KCNN2CaMBD domain-containing protein. (834 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
DDCDopa decarboxylase. (489 aa)
GNB5G protein subunit beta 5. (357 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
KCNJ9Uncharacterized protein. (322 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
HTR3E5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
GNAI3G protein subunit alpha i3. (354 aa)
MAOAAmine oxidase. (527 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2116 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
HTR2BG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (398 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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