STRINGSTRING
PRKAB2 PRKAB2 PRKAB1 PRKAB1 CACNG1 CACNG1 CACNG5 CACNG5 PRKCA PRKCA ADCY3 ADCY3 CAMK1G CAMK1G GNAO1 GNAO1 GNAQ GNAQ ITPR1 ITPR1 LOC100600502 LOC100600502 PLA2G4E PLA2G4E PLA2G4D PLA2G4D NOS3 NOS3 PLA2G4F PLA2G4F PLCB3 PLCB3 KRAS KRAS PRKCG PRKCG GUCY1A1 GUCY1A1 CACNG7 CACNG7 CACNG8 CACNG8 PPP1CA PPP1CA RHOA RHOA GNAI2 GNAI2 GUCY1A2 GUCY1A2 CACNA2D3 CACNA2D3 KCNJ5 KCNJ5 OXT OXT CACNA1F CACNA1F HRAS HRAS MAPK7 MAPK7 PIK3CG PIK3CG PRKAG3 PRKAG3 GNAI1 GNAI1 MYLK2 MYLK2 PIK3R5 PIK3R5 RYR3 RYR3 MYLK4 MYLK4 KCNJ3 KCNJ3 CAMK4 CAMK4 ADCY2 ADCY2 CACNG3 CACNG3 CAMK1D CAMK1D MAP2K5 MAP2K5 CALML4 CALML4 KCNJ12 KCNJ12 PLCB1 PLCB1 PLCB4 PLCB4 CACNG2 CACNG2 PRKAA2 PRKAA2 CACNA2D1 CACNA2D1 PPP1CB PPP1CB PPP3CC PPP3CC CACNB3 CACNB3 PTGS2 PTGS2 PLA2G4A PLA2G4A RGS2 RGS2 LOC100592546 LOC100592546 LOC101176289 LOC101176289 ACTG1 ACTG1 RAF1 RAF1 PPP3R1 PPP3R1 PPP3CB PPP3CB MAPK1 MAPK1 CD38 CD38 CALML3 CALML3 GUCY1B1 GUCY1B1 PRKACB PRKACB CACNB4 CACNB4 KCNJ2 KCNJ2 CALM1 CALM1 PRKAG2 PRKAG2 PRKAG1 PRKAG1 PPP3CA PPP3CA CCND1 CCND1 PPP1R12A PPP1R12A PRKAA1 PRKAA1 ITPR2 ITPR2 MYL9 MYL9 KCNJ14 KCNJ14 NFATC2 NFATC2 CACNG4 CACNG4 ROCK2 ROCK2 EGFR EGFR MAP2K1 MAP2K1 EEF2K EEF2K ADCY8 ADCY8 CACNA2D2 CACNA2D2 NFATC1 NFATC1 KCNJ9 KCNJ9 NRAS NRAS CACNA2D4 CACNA2D4 GNAI3 GNAI3 CAMKK2 CAMKK2 CACNB2 CACNB2 ROCK1 ROCK1 PRKCB PRKCB CACNA1D CACNA1D RCAN1 RCAN1 NFATC3 NFATC3 KCNJ6 KCNJ6 ADCY1 ADCY1 FOS FOS ADCY5 ADCY5 OXTR OXTR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (276 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
GNAO1G protein subunit alpha o1. (353 aa)
GNAQG protein subunit alpha q. (358 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
LOC100600502Guanylate cyclase domain-containing protein. (613 aa)
PLA2G4EPhospholipase A2. (867 aa)
PLA2G4DPhospholipase A2. (818 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
PLA2G4FPhospholipase A2. (850 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (271 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (424 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
RHOARas homolog family member A. (193 aa)
GNAI2G protein subunit alpha i2. (355 aa)
GUCY1A2Uncharacterized protein. (385 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (958 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (418 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (124 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1967 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
GNAI1G protein subunit alpha i1. (353 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (889 aa)
RYR3Ryanodine receptor 3. (4794 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (388 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (966 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
CAMK1DProtein kinase domain-containing protein. (309 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (414 aa)
CALML4Calmodulin like 4. (196 aa)
KCNJ12Uncharacterized protein. (433 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1071 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (444 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
PLA2G4APhospholipase A2. (749 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
LOC100592546ANK_REP_REGION domain-containing protein. (515 aa)
LOC101176289Uncharacterized protein. (244 aa)
ACTG1Actin gamma 1. (378 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
PPP3R1Uncharacterized protein. (189 aa)
PPP3CBSerine/threonine-protein phosphatase. (408 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
CD38CD38 molecule. (300 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (643 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (502 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (333 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
MYL9Myosin light chain 9. (172 aa)
KCNJ14IRK_C domain-containing protein. (239 aa)
NFATC2Nuclear factor of activated T cells 2. (905 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1119 aa)
NFATC1Nuclear factor of activated T cells 1. (968 aa)
KCNJ9Uncharacterized protein. (322 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CACNA2D4VWFA domain-containing protein. (587 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (591 aa)
CACNB2GuKc domain-containing protein. (586 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2116 aa)
RCAN1Uncharacterized protein. (278 aa)
NFATC3Nuclear factor of activated T cells 3. (1045 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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