STRINGSTRING
ADCY3 ADCY3 AGT AGT GNAQ GNAQ MRAP MRAP ITPR1 ITPR1 CREB3 CREB3 PLCB3 PLCB3 HSD3B1 HSD3B1 NCEH1 NCEH1 ATF6B ATF6B CACNA1F CACNA1F NR0B1 NR0B1 PDE8A PDE8A ADCY2 ADCY2 STAR STAR CREB3L2 CREB3L2 PLCB1 PLCB1 PLCB4 PLCB4 KCNK2 KCNK2 CYP17A1 CYP17A1 ATF4 ATF4 NR5A1 NR5A1 SP1 SP1 NR4A1 NR4A1 LOC101176289 LOC101176289 KCNK3 KCNK3 LOC100596087 LOC100596087 HSD3B2 HSD3B2 PRKACB PRKACB MC2R MC2R ENSNLEP00000030218 ENSNLEP00000030218 PBX1 PBX1 ATF2 ATF2 ITPR2 ITPR2 ADCY8 ADCY8 PDE8B PDE8B AGTR1 AGTR1 SCARB1 SCARB1 CACNA1D CACNA1D ADCY1 ADCY1 ADCY5 ADCY5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
GNAQG protein subunit alpha q. (358 aa)
MRAPMelanocortin 2 receptor accessory protein. (172 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
HSD3B1Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (373 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (448 aa)
ATF6BActivating transcription factor 6 beta. (718 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1967 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
PDE8APhosphodiesterase. (829 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (966 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (506 aa)
ATF4BZIP domain-containing protein. (351 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
SP1Sp1 transcription factor. (786 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (589 aa)
LOC101176289Uncharacterized protein. (244 aa)
KCNK3Ion_trans_2 domain-containing protein. (271 aa)
LOC1005960873Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (386 aa)
HSD3B2Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2; Belongs to the 3-beta-HSD family. (372 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
MC2RMelanocortin 2 receptor. (297 aa)
ENSNLEP00000030218Uncharacterized protein. (112 aa)
PBX1PBX homeobox 1. (433 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
PDE8BPhosphodiesterase. (781 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (550 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2116 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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