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PRKCA PRKCA PIK3CB PIK3CB KRAS KRAS NR3C2 NR3C2 PIK3CA PIK3CA PIK3R2 PIK3R2 PRKCG PRKCG LOC100589631 LOC100589631 LOC100592336 LOC100592336 ATP1B2 ATP1B2 ATP1A3 ATP1A3 INS-IGF2 INS-IGF2 SGK1 SGK1 ATP1B1 ATP1B1 ATP1B4 ATP1B4 SFN SFN FXYD4 FXYD4 MAPK1 MAPK1 PIK3R1 PIK3R1 ATP1A1 ATP1A1 KCNJ1 KCNJ1 IRS1 IRS1 ATP1B3 ATP1B3 HSD11B2 HSD11B2 PRKCB PRKCB IGF1 IGF1 PIK3R3 PIK3R3 ATP1A2 ATP1A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (988 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
PIK3R2Uncharacterized protein. (727 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
LOC100589631PDZ domain-containing protein. (226 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (952 aa)
INS-IGF2INS-IGF2 readthrough; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (203 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
FXYD4FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (89 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (420 aa)
IRS1Insulin receptor substrate 1. (1242 aa)
ATP1B3Uncharacterized protein. (89 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (445 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
IGF1IlGF domain-containing protein. (196 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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