STRINGSTRING
PRKCA PRKCA ADCY3 ADCY3 CPB1 CPB1 CPA3 CPA3 CPB2 CPB2 PRSS1 PRSS1 GNAQ GNAQ CA2 CA2 ITPR1 ITPR1 RAP1A RAP1A PLA2G3 PLA2G3 TRPC1 TRPC1 PLCB3 PLCB3 CTRL CTRL CCK CCK PRKCG PRKCG RHOA RHOA CELA2A CELA2A CELA2B CELA2B SLC4A4 SLC4A4 PLA2G2E PLA2G2E PLA2G2A PLA2G2A PLA2G5 PLA2G5 PLA2G2D PLA2G2D RAB27B RAB27B SLC26A3 SLC26A3 SLC9A1 SLC9A1 ATP1B2 ATP1B2 CLCA2 CLCA2 CLCA1 CLCA1 CLCA4 CLCA4 SCTR SCTR ADCY2 ADCY2 CFTR CFTR SLC12A2 SLC12A2 RAB3D RAB3D CEL CEL ATP1A3 ATP1A3 PLCB1 PLCB1 PLCB4 PLCB4 ATP1B1 ATP1B1 ATP1B4 ATP1B4 LOC100594235 LOC100594235 PLA2G1B PLA2G1B CELA3A CELA3A PNLIP PNLIP PNLIPRP1 PNLIPRP1 PNLIPRP2 PNLIPRP2 PLA2G12B PLA2G12B CCKAR CCKAR ATP2B4 ATP2B4 LOC101176289 LOC101176289 CHRM3 CHRM3 RAB11A RAB11A LOC100593892 LOC100593892 CD38 CD38 ATP2B1 ATP2B1 KCNMA1 KCNMA1 ATP2A3 ATP2A3 ATP1A1 ATP1A1 ITPR2 ITPR2 BST1 BST1 CPA2 CPA2 ATP1B3 ATP1B3 ADCY8 ADCY8 ATP2A1 ATP2A1 PRSS2 PRSS2 LOC100592228 LOC100592228 PRKCB PRKCB RAB8A RAB8A ATP2A2 ATP2A2 PLA2G12A PLA2G12A ADCY1 ADCY1 CELA3B CELA3B ATP1A2 ATP1A2 ADCY5 ADCY5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
CPB1Carboxypeptidase B1. (417 aa)
CPA3Carboxypeptidase A3. (417 aa)
CPB2Carboxypeptidase B2. (423 aa)
PRSS1Serine protease 1; Belongs to the peptidase S1 family. (247 aa)
GNAQG protein subunit alpha q. (358 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2755 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (881 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
CTRLChymotrypsin like; Belongs to the peptidase S1 family. (245 aa)
CCKCholecystokinin. (115 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
RHOARas homolog family member A. (193 aa)
CELA2AChymotrypsin like elastase 2A; Belongs to the peptidase S1 family. (269 aa)
CELA2BChymotrypsin like elastase 2B; Belongs to the peptidase S1 family. (269 aa)
SLC4A4Anion exchange protein. (1084 aa)
PLA2G2EPhospholipase A(2). (142 aa)
PLA2G2APhospholipase A(2). (144 aa)
PLA2G5Phospholipase A(2). (138 aa)
PLA2G2DPhospholipase A(2). (144 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (759 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
CLCA2Chloride channel accessory 2. (943 aa)
CLCA1Chloride channel accessory 1. (914 aa)
CLCA4Chloride channel accessory 4. (921 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (440 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (966 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa)
SLC12A2Solute carrier family 12 member 2. (1202 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
CELCarboxyl ester lipase; Belongs to the type-B carboxylesterase/lipase family. (701 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (952 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
LOC100594235Alpha-amylase. (511 aa)
PLA2G1BPhospholipase A(2). (148 aa)
CELA3AChymotrypsin like elastase 3A; Belongs to the peptidase S1 family. (265 aa)
PNLIPTriacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (467 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (469 aa)
PLA2G12BPhospholipase A2 group XIIB. (195 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1241 aa)
LOC101176289Uncharacterized protein. (244 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
RAB11ARAB11A, member RAS oncogene family. (216 aa)
LOC100593892Alpha-amylase. (511 aa)
CD38CD38 molecule. (300 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1289 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (987 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2727 aa)
BST1Bone marrow stromal cell antigen 1. (333 aa)
CPA2Carboxypeptidase A2. (425 aa)
ATP1B3Uncharacterized protein. (89 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1031 aa)
PRSS2Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
LOC100592228Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
RAB8ARAB8A, member RAS oncogene family. (197 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
PLA2G12APhospholipase A2 group XIIA. (189 aa)
ADCY1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (338 aa)
CELA3BPeptidase S1 domain-containing protein. (120 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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