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| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) |
| | MYL2 | Myosin light chain 2. (166 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (368 aa) |
| | PFN4 | Profilin; Belongs to the profilin family. (128 aa) |
| | CYTH3 | Cytohesin 3. (399 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (391 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (517 aa) |
| | VPS33A | VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (596 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) |
| | ELMO1 | Engulfment and cell motility 1. (727 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | ARPC3 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (163 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (813 aa) |
| | RALA | RAS like proto-oncogene A. (206 aa) |
| | VPS18 | VPS18 core subunit of CORVET and HOPS complexes. (972 aa) |
| | RAB5A | RAB5A, member RAS oncogene family. (215 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (335 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1020 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | DYNC1LI1 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | PIK3C2G | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1486 aa) |
| | KPNA4 | Importin subunit alpha; Functions in nuclear protein import. (521 aa) |
| | BAX | Uncharacterized protein. (194 aa) |
| | PLEKHM1 | Pleckstrin homology and RUN domain containing M1. (1056 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | KLC2 | Kinesin light chain 2. (622 aa) |
| | HSP90B1 | Heat shock protein 90 beta family member 1. (804 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | MYL12A | Myosin light chain 12A. (177 aa) |
| | G1R620_NOMLE | TIR domain-containing protein. (1031 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (603 aa) |
| | DYNC2H1 | Dynein cytoplasmic 2 heavy chain 1. (4306 aa) |
| | CASP4 | Caspase 4; Belongs to the peptidase C14A family. (377 aa) |
| | CASP5 | Caspase 5; Belongs to the peptidase C14A family. (448 aa) |
| | FLNB | Filamin B. (2585 aa) |
| | VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (931 aa) |
| | PLEKHM2 | Pleckstrin homology and RUN domain containing M2. (1007 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | FBXO22 | F-box protein 22. (403 aa) |
| | MYL10 | Myosin light chain 10. (226 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) |
| | DYNLRB1 | Robl_LC7 domain-containing protein. (148 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | SNX9 | Sorting nexin. (597 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | ARPC1A | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) |
| | RAB5C | RAB5C, member RAS oncogene family. (249 aa) |
| | ANXA2 | Annexin. (367 aa) |
| | WASL | WASP like actin nucleation promoting factor. (505 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (745 aa) |
| | PODXL | Uncharacterized protein. (644 aa) |
| | EXOC4 | Exocyst complex component 4. (974 aa) |
| | EXOC5 | Exocyst complex component 5. (680 aa) |
| | S100A10 | S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa) |
| | SNX33 | Sorting nexin. (573 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | WASF3 | WASP family member 3. (502 aa) |
| | FLNA | Filamin A. (2626 aa) |
| | ARF1 | ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | IKBKG | NEMO domain-containing protein. (173 aa) |
| | CYCS | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (506 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (471 aa) |
| | TCF7L2 | HMG box domain-containing protein. (534 aa) |
| | DYNC1H1 | Dynein cytoplasmic 1 heavy chain 1. (4646 aa) |
| | DYNC1I1 | Dynein cytoplasmic 1 intermediate chain 1. (645 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | G1S2Z3_NOMLE | Uncharacterized protein. (793 aa) |
| | DYNC2LI1 | Dynein cytoplasmic 2 light intermediate chain 1. (351 aa) |
| | ARPC5L | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa) |
| | PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | ARPC5 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1304 aa) |
| | RAB9B | RAB9B, member RAS oncogene family. (201 aa) |
| | TLR2 | Toll-like receptor. (784 aa) |
| | ACTG1 | Actin gamma 1. (378 aa) |
| | DYNLL1 | Dynein light chain. (89 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (321 aa) |
| | RAB7A | RAB7A, member RAS oncogene family. (207 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (743 aa) |
| | HSP90AA1 | Heat shock protein 90 alpha family class A member 1. (853 aa) |
| | RAB9A | RAB9A, member RAS oncogene family. (201 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | KLC3 | TPR_REGION domain-containing protein. (436 aa) |
| | CSE1L | Chromosome segregation 1 like. (959 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (895 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1228 aa) |
| | CYTH1 | Uncharacterized protein. (344 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | LOC100600457 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LY96 | Lymphocyte antigen 96. (160 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (382 aa) |
| | ARF6 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | MYO6 | Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa) |
| | DYNLRB2 | Dynein light chain roadblock-type 2. (124 aa) |
| | ARHGEF26 | Rho guanine nucleotide exchange factor 26. (869 aa) |
| | CYTH2 | Uncharacterized protein. (400 aa) |
| | LOC100598207 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | MYL12B | Myosin light chain 12B. (172 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1109 aa) |
| | ELMO2 | Engulfment and cell motility 2. (720 aa) |
| | PFN3 | Profilin; Belongs to the profilin family. (137 aa) |
| | NCKAP1 | NCK associated protein 1. (1134 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (386 aa) |
| | MYL9 | Myosin light chain 9. (172 aa) |
| | LOC101179576 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (182 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | LOC100595437 | Thioredoxin domain-containing protein. (105 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | RHOG | Ras homolog family member G. (191 aa) |
| | ACBD3 | Acyl-CoA binding domain containing 3. (528 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | STX10 | Syntaxin 10; Belongs to the syntaxin family. (249 aa) |
| | DYNLT3 | Uncharacterized protein. (151 aa) |
| | ENSNLEP00000037515 | Thioredoxin; Belongs to the thioredoxin family. (105 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (615 aa) |
| | ENSNLEP00000038814 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (107 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (545 aa) |
| | M6PR | Mannose-6-phosphate receptor, cation dependent. (267 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | CDC42 | Cell division cycle 42. (191 aa) |
| | RHOB | Ras homolog family member B. (196 aa) |
| | TIRAP | TIR domain containing adaptor protein. (221 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (404 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | ARPC2 | Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (275 aa) |
| | KPNA3 | Importin subunit alpha; Functions in nuclear protein import. (506 aa) |
| | ARPC4 | Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (187 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | RAB5B | Uncharacterized protein. (228 aa) |
| | PFN1-2 | Profilin; Belongs to the profilin family. (128 aa) |
| | IL6 | Uncharacterized protein. (258 aa) |
| | DYNLL2 | Dynein light chain. (89 aa) |
| | TCF7 | HMG box domain-containing protein. (486 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | LOC100603153 | Uncharacterized protein. (445 aa) |
| | RPS3 | Ribosomal_S3_C domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (190 aa) |
