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| | BIRC5 | Uncharacterized protein. (91 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (368 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (391 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1461 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (764 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1139 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | RB1 | RB transcriptional corepressor 1. (919 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (371 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | BAX | Uncharacterized protein. (194 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa) |
| | PIK3R2 | Uncharacterized protein. (727 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa) |
| | ATF6B | Activating transcription factor 6 beta. (718 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) |
| | STAT4 | Signal transducer and activator of transcription. (748 aa) |
| | MMP9 | Matrix metallopeptidase 9. (692 aa) |
| | CASP10 | Caspase 10; Belongs to the peptidase C14A family. (523 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (402 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (426 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | IRF7 | Interferon regulatory factor 7. (524 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (431 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | E2F1 | E2F transcription factor 1. (391 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | TICAM2 | Toll like receptor adaptor molecule 2. (234 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | TYK2 | Tyrosine-protein kinase. (1181 aa) |
| | FAS | Fas cell surface death receptor. (335 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (745 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (284 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (691 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | YWHAQ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (253 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (468 aa) |
| | IKBKG | NEMO domain-containing protein. (173 aa) |
| | CYCS | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | JAK1 | Tyrosine-protein kinase. (1149 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | ATF4 | BZIP domain-containing protein. (351 aa) |
| | FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | STAT6 | Signal transducer and activator of transcription. (842 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | TLR2 | Toll-like receptor. (784 aa) |
| | G1SBE5_NOMLE | Uncharacterized protein. (198 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (976 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | M3ZBW0_NOMLE | SH2 domain-containing protein. (230 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (321 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (743 aa) |
| | STAT2 | Signal transducer and activator of transcription. (852 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (550 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (410 aa) |
| | LOC100595932 | Uncharacterized protein. (198 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (704 aa) |
| | YWHAZ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa) |
| | IFNA8 | Interferon alpha 8. (189 aa) |
| | INSL3 | Insulin like 3. (157 aa) |
| | LOC100600457 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (382 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (716 aa) |
| | LOC100598207 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | LOC101179576 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (905 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (214 aa) |
| | BAD | Uncharacterized protein. (82 aa) |
| | ENSNLEP00000038814 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (107 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (968 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (557 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | E2F3 | E2F transcription factor 3. (397 aa) |
| | IFNA5 | Interferon alpha 5. (189 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | TIRAP | TIR domain containing adaptor protein. (221 aa) |
| | EGR2 | Early growth response 2. (476 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1045 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (478 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | IL6 | Uncharacterized protein. (258 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
