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| | OAS3 | 2'-5'-oligoadenylate synthetase 3. (1072 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (719 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa) |
| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | LOC100586612 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (194 aa) |
| | KPNA2 | Importin subunit alpha; Functions in nuclear protein import. (499 aa) |
| | RAB11B | RAB11B, member RAS oncogene family. (218 aa) |
| | PRSS1 | Serine protease 1; Belongs to the peptidase S1 family. (247 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (314 aa) |
| | NXF1 | Uncharacterized protein. (404 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1020 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa) |
| | TRADD | TNFRSF1A associated via death domain. (311 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | BAX | Uncharacterized protein. (194 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa) |
| | PIK3R2 | Uncharacterized protein. (727 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |
| | HLA-DQA2 | Major histocompatibility complex, class II, DQ alpha 2; Belongs to the MHC class II family. (255 aa) |
| | LOC100606816 | Ig-like domain-containing protein. (263 aa) |
| | HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (258 aa) |
| | TMPRSS4 | Transmembrane serine protease 4; Belongs to the peptidase S1 family. (435 aa) |
| | LOC100598965 | Uncharacterized protein. (626 aa) |
| | NXF3 | Nuclear RNA export factor 3. (531 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (426 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (282 aa) |
| | CXCL10 | C-X-C motif chemokine. (98 aa) |
| | IRF7 | Interferon regulatory factor 7. (524 aa) |
| | MX2 | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (645 aa) |
| | TMPRSS2 | Transmembrane serine protease 2; Belongs to the peptidase S1 family. (530 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | TLR7 | Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa) |
| | IL33 | Interleukin 33. (270 aa) |
| | TMPRSS11D | Transmembrane protease serine; Belongs to the peptidase S1 family. (418 aa) |
| | XPO1 | Exportin 1. (1091 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | KPNA7 | Importin subunit alpha; Functions in nuclear protein import. (516 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | PLG | Apple domain-containing protein. (97 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | ADAR | Adenosine deaminase RNA specific. (1180 aa) |
| | FDPS | Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (420 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (531 aa) |
| | TYK2 | Tyrosine-protein kinase. (1181 aa) |
| | FAS | Fas cell surface death receptor. (335 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (745 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (691 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | SLC25A31 | Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa) |
| | HNRNPUL1 | Heterogeneous nuclear ribonucleoprotein U like 1. (854 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | IKBKG | NEMO domain-containing protein. (173 aa) |
| | NXT2 | Nuclear transport factor 2 like export factor 2. (197 aa) |
| | SLC25A5 | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | CYCS | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | JAK1 | Tyrosine-protein kinase. (1149 aa) |
| | FASLG | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa) |
| | IRF9 | Interferon regulatory factor 9. (392 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (361 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (471 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | RNASEL | Ribonuclease L. (741 aa) |
| | G1SBE5_NOMLE | Uncharacterized protein. (198 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | ACTG1 | Actin gamma 1. (378 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (976 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (743 aa) |
| | RAB11A | RAB11A, member RAS oncogene family. (216 aa) |
| | STAT2 | Signal transducer and activator of transcription. (852 aa) |
| | LOC100595932 | Uncharacterized protein. (198 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa) |
| | IFNA8 | Interferon alpha 8. (189 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (455 aa) |
| | LOC100600457 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | MX1 | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (671 aa) |
| | HLA-DQA1 | Major histocompatibility complex, class II, DQ alpha 1; Belongs to the MHC class II family. (255 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (716 aa) |
| | KPNA5 | Importin subunit alpha; Functions in nuclear protein import. (539 aa) |
| | LOC100598207 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC101179576 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (182 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (292 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (214 aa) |
| | DNAJC3 | DnaJ heat shock protein family (Hsp40) member C3. (504 aa) |
| | OAS1 | 2'-5'-oligoadenylate synthetase 1. (400 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (489 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | ENSNLEP00000038814 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (107 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (273 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | PRSS2 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (557 aa) |
| | CCND3 | Uncharacterized protein; Belongs to the cyclin family. (242 aa) |
| | LOC100592228 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa) |
| | IFNA5 | Interferon alpha 5. (189 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | HLA-DQB1 | Major histocompatibility complex, class II, DQ beta 1. (269 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (404 aa) |
| | TRIM25 | Tripartite motif containing 25. (630 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (478 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | PML | Uncharacterized protein. (873 aa) |
| | IL6 | Uncharacterized protein. (258 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | SLC25A4 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (366 aa) |
