STRINGSTRING
ITGA2B ITGA2B TBP TBP MPP5 MPP5 RPS6KB1 RPS6KB1 COL9A1 COL9A1 ATP6V1B2 ATP6V1B2 RBL2 RBL2 FOXO1 FOXO1 THBS2 THBS2 TCF7L1 TCF7L1 ATP6V0D2 ATP6V0D2 MAML1 MAML1 LAMB3 LAMB3 COL6A5 COL6A5 COL6A6 COL6A6 ATP6V0A2 ATP6V0A2 HDAC1 HDAC1 WNT5B WNT5B RB1 RB1 VWF VWF CCNE2 CCNE2 PPP2R3C PPP2R3C ATP6V1C1 ATP6V1C1 FZD6 FZD6 PPP2R3A PPP2R3A WNT2B WNT2B TADA3 TADA3 CREB3 CREB3 TRADD TRADD PIK3CB PIK3CB CHD4 CHD4 RHEB RHEB PPP2R5D PPP2R5D ATP6V1A ATP6V1A BAX BAX PARD6A PARD6A WNT3 WNT3 WNT9B WNT9B LOC100592911 LOC100592911 MAML3 MAML3 NFX1 NFX1 KRAS KRAS NOTCH2 NOTCH2 PIK3CA PIK3CA CTNNB1 CTNNB1 PIK3R2 PIK3R2 COMP COMP LOC100579523 LOC100579523 RBL1 RBL1 ITGA4 ITGA4 TCIRG1 TCIRG1 LAMA3 LAMA3 LAMA1 LAMA1 PARD6B PARD6B WNT5A WNT5A FN1 FN1 CCNE1 CCNE1 UBR4 UBR4 COL4A1 COL4A1 WNT4 WNT4 HRAS HRAS LAMB4 LAMB4 LAMB1 LAMB1 MX2 MX2 WNT6 WNT6 WNT10A WNT10A COL1A1 COL1A1 RELN RELN CCNA2 CCNA2 ATP6V0C ATP6V0C IBSP IBSP CREBBP CREBBP COL9A3 COL9A3 E2F1 E2F1 PDGFRB PDGFRB SLC9A3R1 SLC9A3R1 FADD FADD ITGA1 ITGA1 CASP3 CASP3 COL6A3 COL6A3 TLR3 TLR3 ATP6V0A1 ATP6V0A1 APC APC WNT2 WNT2 TUBG1 TUBG1 PPP2R2C PPP2R2C WNT16 WNT16 HEYL HEYL PPP2CB PPP2CB SOS2 SOS2 PTEN PTEN COL9A2 COL9A2 TYK2 TYK2 FAS FAS ITGA8 ITGA8 LAMC3 LAMC3 IRF1 IRF1 TBPL2 TBPL2 IKBKB IKBKB TSC1 TSC1 LAMA4 LAMA4 ITGA11 ITGA11 TICAM1 TICAM1 COL4A4 COL4A4 NFKB1 NFKB1 BCAP31 BCAP31 WNT7B WNT7B CREB3L2 CREB3L2 ATP6V0A4 ATP6V0A4 HEY2 HEY2 PPP2R5E PPP2R5E ATP6AP1 ATP6AP1 IKBKG IKBKG TBPL1 TBPL1 WNT8B WNT8B MFNG MFNG AXIN2 AXIN2 JAK1 JAK1 FASLG FASLG IRF9 IRF9 TNN TNN TNR TNR COL1A2 COL1A2 CCNA1 CCNA1 TCF7L2 TCF7L2 TRAF3 TRAF3 PTGER4 PTGER4 SOS1 SOS1 EGF EGF FZD3 FZD3 ATP6V1G1 ATP6V1G1 WNT11 WNT11 TNC TNC RBPJ RBPJ PSMC1 PSMC1 TBK1 TBK1 CDK4 CDK4 ITGA5 ITGA5 ITGB7 ITGB7 WNT1 WNT1 COL2A1 COL2A1 LAMC1 LAMC1 PTGS2 PTGS2 LOC101176289 LOC101176289 CSNK1A1L CSNK1A1L FZD9 FZD9 FZD10 FZD10 G1SBE5_NOMLE G1SBE5_NOMLE IFNB1 IFNB1 PRKCI PRKCI AKT3 AKT3 DVL3 DVL3 CDK6 CDK6 RAF1 RAF1 COL4A6 COL4A6 CDKN1B CDKN1B CHUK CHUK ENSNLEP00000025590 ENSNLEP00000025590 ATR ATR STAT2 STAT2 ITGB6 ITGB6 GSK3B GSK3B WNT3A WNT3A MAML2 MAML2 LOC100595932 LOC100595932 IFNA6 IFNA6 MAPK1 MAPK1 ATP6V1G2 ATP6V1G2 AKT1 AKT1 PARD3 PARD3 DLG1 DLG1 PRKACB PRKACB IFNA8 IFNA8 ENSNLEP00000029648 ENSNLEP00000029648 TNFRSF1A TNFRSF1A MX1 MX1 OASL OASL LAMC2 LAMC2 ATP6V0E1 ATP6V0E1 ITGB1 ITGB1 PSEN1 PSEN1 FZD7 FZD7 PPP2R2D PPP2R2D CCND1 CCND1 PIK3R1 PIK3R1 PPP2R1B PPP2R1B ITGB3 ITGB3 HES7 HES7 MTOR MTOR BAK1 BAK1 HEY1 HEY1 FZD4 FZD4 EGFR EGFR PPP2R5A PPP2R5A MAP2K1 MAP2K1 LAMA2 LAMA2 RELA RELA PPP2R1A PPP2R1A WNT8A WNT8A ITGA6 ITGA6 ATP6V1H ATP6V1H COL4A5 COL4A5 CHAD CHAD BAD BAD HDAC2 HDAC2 ATP6V0E2 ATP6V0E2 TUBG2 TUBG2 TSC2 TSC2 ITGA10 ITGA10 DLG2 DLG2 NRAS NRAS RFNG RFNG CASP8 CASP8 GRB2 GRB2 IFNAR1 IFNAR1 CDC42 CDC42 CRB3 CRB3 CCND3 CCND3 PPP2CA PPP2CA PPP2R2A PPP2R2A DVL1 DVL1 ATP6V1D ATP6V1D ITGA2 ITGA2 IFNA5 IFNA5 THBS1 THBS1 FZD2 FZD2 PPP2R2B PPP2R2B PIK3R3 PIK3R3 ITGB5 ITGB5 ITGA9 ITGA9 UBE3A UBE3A COL4A3 COL4A3 FZD5 FZD5 TCF7 TCF7 TNF TNF PXN PXN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1040 aa)
TBPTATA-box binding protein. (328 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (513 aa)
COL9A1Collagen type IX alpha 1 chain. (921 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (528 aa)
RBL2RB transcriptional corepressor like 2. (1138 aa)
FOXO1Forkhead box O1. (652 aa)
THBS2Thrombospondin 2. (1101 aa)
TCF7L1Transcription factor 7 like 1. (517 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
MAML1Mastermind like transcriptional coactivator 1. (1016 aa)
LAMB3Laminin subunit beta 3. (1137 aa)
COL6A5Collagen type VI alpha 5 chain. (2590 aa)
COL6A6Collagen type VI alpha 6 chain. (2233 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
RB1RB transcriptional corepressor 1. (919 aa)
VWFVon Willebrand factor. (2790 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
PPP2R3CProtein phosphatase 2 regulatory subunit B''gamma. (453 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
PPP2R3AProtein phosphatase 2 regulatory subunit B''alpha. (1150 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
TADA3Transcriptional adaptor 3. (440 aa)
CREB3cAMP responsive element binding protein 3. (371 aa)
TRADDTNFRSF1A associated via death domain. (311 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
CHD4Uncharacterized protein. (1987 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (607 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (617 aa)
BAXUncharacterized protein. (194 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
LOC100592911Ig-like domain-containing protein; Belongs to the MHC class I family. (295 aa)
MAML3Mastermind like transcriptional coactivator 3. (1133 aa)
NFX1Nuclear transcription factor, X-box binding 1. (1120 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
NOTCH2Notch receptor 2. (2444 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
CTNNB1Catenin beta 1. (781 aa)
PIK3R2Uncharacterized protein. (727 aa)
COMPTSP C-terminal domain-containing protein. (194 aa)
LOC100579523Major histocompatibility complex, class I, B; Belongs to the MHC class I family. (365 aa)
RBL1RB transcriptional corepressor like 1. (1068 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (832 aa)
LAMA3Laminin subunit alpha 3. (3316 aa)
LAMA1Laminin subunit alpha 1. (3033 aa)
PARD6BPar-6 family cell polarity regulator beta. (372 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
FN1Fibronectin 1. (2477 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (402 aa)
UBR4Ubiquitin protein ligase E3 component n-recognin 4. (5170 aa)
COL4A1Collagen type IV alpha 1 chain. (1629 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (207 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
LAMB4Laminin subunit beta 4. (1753 aa)
LAMB1Laminin subunit beta 1. (1810 aa)
MX2MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (645 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
COL1A1Collagen type I alpha 1 chain. (1386 aa)
RELNReelin. (3460 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (431 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
IBSPIntegrin binding sialoprotein. (317 aa)
CREBBPCREB binding protein. (2442 aa)
COL9A3Uncharacterized protein. (589 aa)
E2F1E2F transcription factor 1. (391 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
SLC9A3R1Uncharacterized protein. (276 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
COL6A3Collagen type VI alpha 3 chain. (3149 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (825 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
TUBG1Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (464 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (279 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
COL9A2Collagen type IX alpha 2 chain. (661 aa)
TYK2Tyrosine-protein kinase. (1181 aa)
FASFas cell surface death receptor. (335 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1048 aa)
LAMC3Laminin subunit gamma 3. (1550 aa)
IRF1Interferon regulatory factor. (324 aa)
TBPL2TATA-box binding protein like 2. (375 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
TSC1TSC complex subunit 1. (1164 aa)
LAMA4Laminin subunit alpha 4. (1823 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1188 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (691 aa)
COL4A4Collagen type IV alpha 4 chain. (1678 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
BCAP31Uncharacterized protein. (246 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (447 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (468 aa)
IKBKGNEMO domain-containing protein. (173 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (320 aa)
AXIN2DIX domain-containing protein. (294 aa)
JAK1Tyrosine-protein kinase. (1149 aa)
FASLGTumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa)
IRF9Interferon regulatory factor 9. (392 aa)
TNNTenascin N. (1299 aa)
TNRTenascin R. (1348 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
TCF7L2HMG box domain-containing protein. (534 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TNCTenascin C. (2207 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (527 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
TBK1TANK binding kinase 1. (729 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1038 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (799 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
LAMC1Laminin subunit gamma 1. (1608 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
LOC101176289Uncharacterized protein. (244 aa)
CSNK1A1LCasein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
G1SBE5_NOMLEUncharacterized protein. (198 aa)
IFNB1Interferon beta 1. (187 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
DVL3Dishevelled segment polarity protein 3. (673 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
COL4A6Collagen type IV alpha 6 chain. (1705 aa)
CDKN1BUncharacterized protein. (204 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (743 aa)
ENSNLEP00000025590Ig-like domain-containing protein; Belongs to the MHC class I family. (340 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2620 aa)
STAT2Signal transducer and activator of transcription. (852 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
MAML2Uncharacterized protein. (593 aa)
LOC100595932Uncharacterized protein. (198 aa)
IFNA6Interferon alpha 6. (190 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
PARD3Par-3 family cell polarity regulator. (1273 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (916 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
IFNA8Interferon alpha 8. (189 aa)
ENSNLEP00000029648Ig-like domain-containing protein; Belongs to the MHC class I family. (411 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
MX1Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (671 aa)
OASL2'-5'-oligoadenylate synthetase like. (514 aa)
LAMC2Laminin subunit gamma 2. (1178 aa)
ATP6V0E1Uncharacterized protein. (46 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (444 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (666 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (806 aa)
HES7Hes family bHLH transcription factor 7. (225 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
BAK1BCL2 antagonist/killer 1. (182 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LAMA2Laminin subunit alpha 2. (3062 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (588 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
COL4A5Collagen type IV alpha 5 chain. (1691 aa)
CHADChondroadherin. (363 aa)
BADUncharacterized protein. (82 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (533 aa)
ATP6V0E2Uncharacterized protein. (180 aa)
TUBG2Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (466 aa)
TSC2TSC complex subunit 2. (1777 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
DLG2Discs large MAGUK scaffold protein 2. (975 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
RFNGUncharacterized protein. (205 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (557 aa)
CDC42Cell division cycle 42. (191 aa)
CRB3Crumbs cell polarity complex component 3. (123 aa)
CCND3Uncharacterized protein; Belongs to the cyclin family. (242 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (445 aa)
DVL1Dishevelled segment polarity protein 1. (667 aa)
ATP6V1DATPase H+ transporting V1 subunit D. (247 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
IFNA5Interferon alpha 5. (189 aa)
THBS1Thrombospondin 1. (1173 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (859 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (881 aa)
COL4A3Collagen type IV alpha 3 chain. (1600 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
TCF7HMG box domain-containing protein. (486 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
PXNUncharacterized protein. (1078 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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