STRINGSTRING
GADD45G GADD45G TCF7L1 TCF7L1 BRAF BRAF BAX BAX KRAS KRAS CDH1 CDH1 MYC MYC CTNNB1 CTNNB1 RXRB RXRB HRAS HRAS GADD45A GADD45A RXRG RXRG RET RET TCF7L2 TCF7L2 TPR TPR MAPK1 MAPK1 CCND1 CCND1 LEF1 LEF1 NCOA4 NCOA4 BAK1 BAK1 MAP2K1 MAP2K1 PPARG PPARG TPM3 TPM3 NRAS NRAS POLK POLK NTRK1 NTRK1 TCF7 TCF7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GADD45GGrowth arrest and DNA damage inducible gamma. (159 aa)
TCF7L1Transcription factor 7 like 1. (517 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
BAXUncharacterized protein. (194 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (883 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
CTNNB1Catenin beta 1. (781 aa)
RXRBRetinoid X receptor beta. (537 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
RXRGRetinoid X receptor gamma. (463 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
TCF7L2HMG box domain-containing protein. (534 aa)
TPRTranslocated promoter region, nuclear basket protein. (2354 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
LEF1Lymphoid enhancer binding factor 1. (386 aa)
NCOA4Nuclear receptor coactivator 4. (651 aa)
BAK1BCL2 antagonist/killer 1. (182 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
TPM3Uncharacterized protein; Belongs to the tropomyosin family. (285 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
POLKDNA polymerase kappa. (896 aa)
NTRK1Tyrosine-protein kinase receptor. (787 aa)
TCF7HMG box domain-containing protein. (486 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.