Your Input: | |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (513 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | TCF7L1 | Transcription factor 7 like 1. (517 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (764 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | RB1 | RB transcriptional corepressor 1. (919 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | RARB | Retinoic acid receptor beta. (448 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa) |
| | FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | BAX | Uncharacterized protein. (194 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa) |
| | MLH1 | MutL homolog 1. (756 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | CDH1 | Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (883 aa) |
| | GAB1 | GRB2 associated binding protein 1. (724 aa) |
| | REG4 | Regenerating family member 4. (158 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | PIK3R2 | Uncharacterized protein. (727 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | RXRB | Retinoid X receptor beta. (537 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (402 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (207 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (267 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | E2F1 | E2F transcription factor 1. (391 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | JUP | Junction plakoglobin. (730 aa) |
| | SHC1 | SHC adaptor protein 1. (542 aa) |
| | APC | APC regulator of WNT signaling pathway. (2844 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | CTNNA3 | Catenin alpha 3. (895 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | RXRG | Retinoid X receptor gamma. (463 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | AXIN2 | DIX domain-containing protein. (294 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa) |
| | ABCB1 | ATP binding cassette subfamily B member 1. (1273 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (452 aa) |
| | TCF7L2 | HMG box domain-containing protein. (534 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (820 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa) |
| | CSNK1A1L | Casein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | FRAT2 | FRAT regulator of WNT signaling pathway 2. (232 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (673 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | CDKN1B | Uncharacterized protein. (204 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1413 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (716 aa) |
| | CTNNA1 | Catenin alpha 1. (895 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (386 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (182 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1206 aa) |
| | SHC3 | SHC adaptor protein 3. (598 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (287 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | E2F3 | E2F transcription factor 3. (397 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (667 aa) |
| | POLK | DNA polymerase kappa. (896 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (478 aa) |
| | MUC2 | Uncharacterized protein. (1539 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) |
| | TCF7 | HMG box domain-containing protein. (486 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (138 aa) |
| | CDH17 | Cadherin 17. (832 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1247 aa) |
