STRINGSTRING
PRKCA PRKCA RPS6KB1 RPS6KB1 LYPLA1 LYPLA1 CHKB CHKB PCYT1A PCYT1A PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F PIK3CB PIK3CB RHEB RHEB KRAS KRAS PIK3CA PIK3CA PIK3R2 PIK3R2 PRKCG PRKCG CHPT1 CHPT1 CHKA CHKA DGKG DGKG WAS WAS DGKE DGKE DGKK DGKK PIP5K1B PIP5K1B PDGFA PDGFA HRAS HRAS DGKD DGKD LOC100592336 LOC100592336 SLC44A5 SLC44A5 PDGFRB PDGFRB SLC5A7 SLC5A7 SLC22A3 SLC22A3 SOS2 SOS2 SLC22A4 SLC22A4 SLC22A5 SLC22A5 WASF1 WASF1 TSC1 TSC1 RALGDS RALGDS WASF3 WASF3 PDGFB PDGFB DGKB DGKB SOS1 SOS1 EGF EGF PLD2 PLD2 SP1 SP1 PLA2G4A PLA2G4A AKT3 AKT3 RAF1 RAF1 PDGFD PDGFD MAPK10 MAPK10 MAPK1 MAPK1 AKT1 AKT1 DGKZ DGKZ DGKA DGKA MAPK9 MAPK9 PIK3R1 PIK3R1 MTOR MTOR EGFR EGFR MAP2K1 MAP2K1 GPCPD1 GPCPD1 PCYT1B PCYT1B TSC2 TSC2 PDGFC PDGFC NRAS NRAS PLPP3 PLPP3 GRB2 GRB2 PIP5K1A PIP5K1A ENSNLEP00000041829 ENSNLEP00000041829 RAC2 RAC2 PLD1 PLD1 SLC22A1 SLC22A1 SLC44A1 SLC44A1 PRKCB PRKCB PIK3R3 PIK3R3 MAPK8 MAPK8 DGKI DGKI LOC100581783 LOC100581783 FOS FOS SLC44A3 SLC44A3 HIF1A HIF1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (513 aa)
LYPLA1Abhydrolase_2 domain-containing protein. (230 aa)
CHKBCholine kinase beta. (392 aa)
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (378 aa)
PLA2G4EPhospholipase A2. (867 aa)
PLA2G4DPhospholipase A2. (818 aa)
PLA2G4FPhospholipase A2. (850 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1084 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
PIK3R2Uncharacterized protein. (727 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
CHPT1Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (334 aa)
CHKACholine kinase alpha. (438 aa)
DGKGDiacylglycerol kinase. (791 aa)
WASWASP actin nucleation promoting factor. (502 aa)
DGKEDiacylglycerol kinase. (464 aa)
DGKKDiacylglycerol kinase. (1534 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (572 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
DGKDDiacylglycerol kinase. (1185 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
SLC44A5Solute carrier family 44 member 5; Belongs to the CTL (choline transporter-like) family. (719 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
SLC5A7Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (580 aa)
SLC22A3MFS domain-containing protein. (368 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
SLC22A4Solute carrier family 22 member 4. (551 aa)
SLC22A5Solute carrier family 22 member 5. (580 aa)
WASF1WASP family member 1. (547 aa)
TSC1TSC complex subunit 1. (1164 aa)
RALGDSUncharacterized protein. (916 aa)
WASF3WASP family member 3. (502 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (233 aa)
DGKBDiacylglycerol kinase. (804 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
PLD2Phospholipase. (933 aa)
SP1Sp1 transcription factor. (786 aa)
PLA2G4APhospholipase A2. (749 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
PDGFDPlatelet derived growth factor D. (370 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
DGKZDiacylglycerol kinase. (895 aa)
DGKADiacylglycerol kinase. (743 aa)
MAPK9Mitogen-activated protein kinase. (382 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
GPCPD1Glycerophosphocholine phosphodiesterase 1. (667 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (369 aa)
TSC2TSC complex subunit 2. (1777 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PLPP3acidPPc domain-containing protein. (289 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
ENSNLEP00000041829PIPK domain-containing protein. (329 aa)
RAC2Rac family small GTPase 2. (192 aa)
PLD1Phospholipase. (1074 aa)
SLC22A1Uncharacterized protein. (142 aa)
SLC44A1Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family. (720 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (478 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
DGKIDiacylglycerol kinase. (1026 aa)
LOC100581783Abhydrolase_2 domain-containing protein. (232 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
SLC44A3Solute carrier family 44 member 3; Belongs to the CTL (choline transporter-like) family. (660 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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