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PRKAB2 PRKAB2 ITGA2B ITGA2B PRKAB1 PRKAB1 CACNG1 CACNG1 CACNG5 CACNG5 MYL2 MYL2 EDN1 EDN1 AGT AGT TPM2 TPM2 CACNG7 CACNG7 CACNG8 CACNG8 ITGA4 ITGA4 DAG1 DAG1 LAMA1 LAMA1 CACNA2D3 CACNA2D3 CACNA1F CACNA1F PRKAG3 PRKAG3 SGCA SGCA TNNI3 TNNI3 ITGA1 ITGA1 ACTC1 ACTC1 CACNG3 CACNG3 ITGA8 ITGA8 ITGA11 ITGA11 SGCG SGCG TGFB1 TGFB1 EMD EMD MYBPC3 MYBPC3 CACNG2 CACNG2 PRKAA2 PRKAA2 CACNA2D1 CACNA2D1 TGFB3 TGFB3 ITGA5 ITGA5 ITGB7 ITGB7 CACNB3 CACNB3 ACTG1 ACTG1 SGCB SGCB ITGB6 ITGB6 SGCD SGCD TNNT2 TNNT2 CACNB4 CACNB4 PRKAG2 PRKAG2 SLC8A1 SLC8A1 PRKAG1 PRKAG1 ITGB1 ITGB1 ATP2A3 ATP2A3 ITGB3 ITGB3 TPM1 TPM1 PRKAA1 PRKAA1 DMD DMD DES DES CACNG4 CACNG4 LAMA2 LAMA2 ITGA6 ITGA6 TTN TTN TPM3 TPM3 ATP2A1 ATP2A1 CACNA2D2 CACNA2D2 ITGA10 ITGA10 CACNA2D4 CACNA2D4 ITGA2 ITGA2 CACNB2 CACNB2 CACNA1D CACNA1D IGF1 IGF1 ITGB5 ITGB5 ATP2A2 ATP2A2 ITGA9 ITGA9 LMNA LMNA SLC8A3 SLC8A3 IL6 IL6 TNF TNF ACE ACE MYL3 MYL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1040 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (276 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
MYL2Myosin light chain 2. (166 aa)
EDN1Endothelin 1. (211 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
TPM2Tropomyosin 2; Belongs to the tropomyosin family. (284 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (271 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (424 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
DAG1Dystroglycan 1. (895 aa)
LAMA1Laminin subunit alpha 1. (3033 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (958 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1967 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
SGCASarcoglycan alpha. (387 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1048 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1188 aa)
SGCGSarcoglycan gamma. (291 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
EMDEmerin. (254 aa)
MYBPC3Uncharacterized protein. (789 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1071 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1038 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (799 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (444 aa)
ACTG1Actin gamma 1. (378 aa)
SGCBSarcoglycan beta. (317 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SGCDSarcoglycan delta. (290 aa)
TNNT2Uncharacterized protein. (339 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (502 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (972 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (333 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (987 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (806 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
DMDDystrophin. (3685 aa)
DESDesmin; Belongs to the intermediate filament family. (487 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
LAMA2Laminin subunit alpha 2. (3062 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
TTNUncharacterized protein. (579 aa)
TPM3Uncharacterized protein; Belongs to the tropomyosin family. (285 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1031 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1119 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
CACNA2D4VWFA domain-containing protein. (587 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
CACNB2GuKc domain-containing protein. (586 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2116 aa)
IGF1IlGF domain-containing protein. (196 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (859 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
IL6Uncharacterized protein. (258 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ACEAngiotensin-converting enzyme. (1202 aa)
MYL3EF-hand domain-containing protein. (161 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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