(15 nodes) Nicotinate and nicotinamide metabolism network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_10265	Deacetylase sirtuin-type domain-containing protein. (374 aa)
	T265_08022	Uncharacterized protein. (301 aa)
	T265_14142	Deacetylase sirtuin-type domain-containing protein. (349 aa)
	T265_08021	Uncharacterized protein. (299 aa)
	T265_04810	Uncharacterized protein. (1109 aa)
	T265_03573	Deacetylase sirtuin-type domain-containing protein. (477 aa)
	T265_04362	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (1480 aa)
	T265_04278	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (307 aa)
	T265_05947	Deacetylase sirtuin-type domain-containing protein. (510 aa)
	T265_15604	Deacetylase sirtuin-type domain-containing protein. (466 aa)
	T265_00471	Uncharacterized protein. (515 aa)
	T265_08445	Deacetylase sirtuin-type domain-containing protein. (947 aa)
	T265_06650	Uncharacterized protein. (367 aa)
	T265_05433	Uncharacterized protein. (786 aa)
	T265_00541	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (770 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00471	T265_00541	A0A075A655	A0A075AJM7	Uncharacterized protein.	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	0.521
T265_00471	T265_03573	A0A075A655	A0A074ZRX7	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.924
T265_00471	T265_04278	A0A075A655	A0A074ZT22	Uncharacterized protein.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.916
T265_00471	T265_04362	A0A075A655	A0A074ZST3	Uncharacterized protein.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.900
T265_00471	T265_05947	A0A075A655	A0A074ZU15	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.929
T265_00471	T265_08021	A0A075A655	A0A074ZF73	Uncharacterized protein.	Uncharacterized protein.	0.924
T265_00471	T265_08022	A0A075A655	A0A074ZAY6	Uncharacterized protein.	Uncharacterized protein.	0.904
T265_00471	T265_08445	A0A075A655	A0A075A8D7	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.958
T265_00471	T265_10265	A0A075A655	A0A074Z316	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.933
T265_00471	T265_14142	A0A075A655	A0A074ZEQ5	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.933
T265_00471	T265_15604	A0A075A655	A0A074ZVQ7	Uncharacterized protein.	Deacetylase sirtuin-type domain-containing protein.	0.913
T265_00541	T265_00471	A0A075AJM7	A0A075A655	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Uncharacterized protein.	0.521
T265_00541	T265_03573	A0A075AJM7	A0A074ZRX7	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Deacetylase sirtuin-type domain-containing protein.	0.942
T265_00541	T265_04278	A0A075AJM7	A0A074ZT22	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.945
T265_00541	T265_04362	A0A075AJM7	A0A074ZST3	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.922
T265_00541	T265_04810	A0A075AJM7	A0A074ZLV8	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Uncharacterized protein.	0.906
T265_00541	T265_05433	A0A075AJM7	A0A075AFB2	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Uncharacterized protein.	0.968
T265_00541	T265_05947	A0A075AJM7	A0A074ZU15	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Deacetylase sirtuin-type domain-containing protein.	0.942
T265_00541	T265_06650	A0A075AJM7	A0A075ADE3	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Uncharacterized protein.	0.947
T265_00541	T265_08021	A0A075AJM7	A0A074ZF73	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.	Uncharacterized protein.	0.903