(25 nodes) Mixed, incl. SAGA-type complex, and NR1H2 and NR1H3-mediated signaling network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_11441	USP domain-containing protein; Belongs to the peptidase C19 family. (893 aa)
	T265_11529	Uncharacterized protein. (95 aa)
	T265_12142	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (98 aa)
	T265_12020	Bromo domain-containing protein. (801 aa)
	T265_11848	Uncharacterized protein. (473 aa)
	T265_15035	Uncharacterized protein. (613 aa)
	T265_14817	Uncharacterized protein. (1220 aa)
	T265_13624	C2H2-type domain-containing protein. (444 aa)
	T265_13667	Uncharacterized protein. (1279 aa)
	T265_05617	Uncharacterized protein. (1225 aa)
	T265_13393	SET domain-containing protein. (2339 aa)
	T265_14127	SANT domain-containing protein. (540 aa)
	T265_04064	SGF29 C-terminal domain-containing protein. (210 aa)
	T265_13823	Uncharacterized protein. (210 aa)
	T265_15568	FAT domain-containing protein. (5173 aa)
	T265_04571	SANT domain-containing protein. (1401 aa)
	T265_01798	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (170 aa)
	T265_00630	Uncharacterized protein. (3231 aa)
	T265_00326	Uncharacterized protein. (130 aa)
	T265_02536	Uncharacterized protein. (637 aa)
	T265_08323	Hist_deacetyl domain-containing protein. (604 aa)
	T265_06725	Uncharacterized protein. (874 aa)
	T265_04882	Ubiquitin carboxyl-terminal hydrolase. (446 aa)
	T265_02802	WD_REPEATS_REGION domain-containing protein. (703 aa)
	T265_01666	Uncharacterized protein. (191 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00326	T265_00630	A0A075A2D1	A0A075A2B9	Uncharacterized protein.	Uncharacterized protein.	0.676
T265_00326	T265_02536	A0A075A2D1	A0A075A6G9	Uncharacterized protein.	Uncharacterized protein.	0.632
T265_00326	T265_04064	A0A075A2D1	A0A074ZU17	Uncharacterized protein.	SGF29 C-terminal domain-containing protein.	0.893
T265_00326	T265_04571	A0A075A2D1	A0A074ZZ86	Uncharacterized protein.	SANT domain-containing protein.	0.632
T265_00326	T265_04882	A0A075A2D1	A0A075AFZ0	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase.	0.483
T265_00326	T265_05617	A0A075A2D1	A0A074ZNF3	Uncharacterized protein.	Uncharacterized protein.	0.483
T265_00326	T265_06725	A0A075A2D1	A0A075AD91	Uncharacterized protein.	Uncharacterized protein.	0.820
T265_00326	T265_11441	A0A075A2D1	A0A074YYM6	Uncharacterized protein.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.483
T265_00326	T265_11529	A0A075A2D1	A0A074YYP4	Uncharacterized protein.	Uncharacterized protein.	0.483
T265_00326	T265_11848	A0A075A2D1	A0A074Z7Y4	Uncharacterized protein.	Uncharacterized protein.	0.781
T265_00326	T265_12020	A0A075A2D1	A0A074Z792	Uncharacterized protein.	Bromo domain-containing protein.	0.768
T265_00326	T265_13624	A0A075A2D1	A0A074ZLJ1	Uncharacterized protein.	C2H2-type domain-containing protein.	0.483
T265_00326	T265_13823	A0A075A2D1	A0A074ZV98	Uncharacterized protein.	Uncharacterized protein.	0.483
T265_00326	T265_14127	A0A075A2D1	A0A074ZR86	Uncharacterized protein.	SANT domain-containing protein.	0.765
T265_00326	T265_14817	A0A075A2D1	A0A074ZH95	Uncharacterized protein.	Uncharacterized protein.	0.768
T265_00326	T265_15035	A0A075A2D1	A0A074ZEN7	Uncharacterized protein.	Uncharacterized protein.	0.765
T265_00326	T265_15568	A0A075A2D1	A0A074ZVY9	Uncharacterized protein.	FAT domain-containing protein.	0.781
T265_00630	T265_00326	A0A075A2B9	A0A075A2D1	Uncharacterized protein.	Uncharacterized protein.	0.676
T265_00630	T265_01666	A0A075A2B9	A0A075AIU3	Uncharacterized protein.	Uncharacterized protein.	0.898
T265_00630	T265_01798	A0A075A2B9	A0A075A189	Uncharacterized protein.	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]	0.676