(12 nodes) Inositol phosphate metabolism network (Opisthorchis viverrini)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	T265_16246	DUF3715 domain-containing protein. (138 aa)
	T265_14953	IPPc domain-containing protein. (311 aa)
	T265_09366	Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family. (306 aa)
	T265_09369	Ins134_P3_kin domain-containing protein. (289 aa)
	T265_14432	Kinase; Belongs to the inositol phosphokinase (IPK) family. (400 aa)
	T265_07802	Kinase; Belongs to the inositol phosphokinase (IPK) family. (453 aa)
	T265_05558	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (491 aa)
	T265_02314	DUF3715 domain-containing protein. (1515 aa)
	T265_03185	Kinase; Belongs to the inositol phosphokinase (IPK) family. (327 aa)
	T265_05106	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1186 aa)
	T265_01827	Uncharacterized protein. (439 aa)
	T265_00972	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1621 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00972	T265_02314	A0A075AJB1	A0A074ZVA5	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	DUF3715 domain-containing protein.	0.534
T265_00972	T265_03185	A0A075AJB1	A0A074ZWQ7	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.534
T265_00972	T265_05558	A0A075AJB1	A0A074ZK03	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).	0.962
T265_00972	T265_14432	A0A075AJB1	A0A074ZFK0	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.534
T265_00972	T265_16246	A0A075AJB1	A0A074YTS4	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	DUF3715 domain-containing protein.	0.534
T265_01827	T265_03185	A0A075AIQ6	A0A074ZWQ7	Uncharacterized protein.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.910
T265_01827	T265_05106	A0A075AIQ6	A0A074ZXA5	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.900
T265_01827	T265_07802	A0A075AIQ6	A0A074ZFZ0	Uncharacterized protein.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.919
T265_01827	T265_09366	A0A075AIQ6	A0A074Z664	Uncharacterized protein.	Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family.	0.909
T265_01827	T265_09369	A0A075AIQ6	A0A074ZAG6	Uncharacterized protein.	Ins134_P3_kin domain-containing protein.	0.909
T265_01827	T265_14432	A0A075AIQ6	A0A074ZFK0	Uncharacterized protein.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.920
T265_01827	T265_14953	A0A075AIQ6	A0A074Z4K4	Uncharacterized protein.	IPPc domain-containing protein.	0.923
T265_02314	T265_00972	A0A074ZVA5	A0A075AJB1	DUF3715 domain-containing protein.	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	0.534
T265_02314	T265_05558	A0A074ZVA5	A0A074ZK03	DUF3715 domain-containing protein.	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).	0.459
T265_03185	T265_00972	A0A074ZWQ7	A0A075AJB1	Kinase; Belongs to the inositol phosphokinase (IPK) family.	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]	0.534
T265_03185	T265_01827	A0A074ZWQ7	A0A075AIQ6	Kinase; Belongs to the inositol phosphokinase (IPK) family.	Uncharacterized protein.	0.910
T265_03185	T265_05106	A0A074ZWQ7	A0A074ZXA5	Kinase; Belongs to the inositol phosphokinase (IPK) family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.900
T265_03185	T265_05558	A0A074ZWQ7	A0A074ZK03	Kinase; Belongs to the inositol phosphokinase (IPK) family.	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).	0.943
T265_03185	T265_07802	A0A074ZWQ7	A0A074ZFZ0	Kinase; Belongs to the inositol phosphokinase (IPK) family.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.909
T265_03185	T265_09366	A0A074ZWQ7	A0A074Z664	Kinase; Belongs to the inositol phosphokinase (IPK) family.	Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family.	0.901