STRINGSTRING
T265_15656 T265_15656 MED10 MED10 T265_11575 T265_11575 T265_16169 T265_16169 T265_10741 T265_10741 T265_10596 T265_10596 T265_15460 T265_15460 T265_11289 T265_11289 T265_15357 T265_15357 T265_10984 T265_10984 T265_16012 T265_16012 T265_10740 T265_10740 T265_15236 T265_15236 T265_10348 T265_10348 T265_10272 T265_10272 T265_10196 T265_10196 T265_10164 T265_10164 T265_08806 T265_08806 T265_08694 T265_08694 T265_09892 T265_09892 T265_09833 T265_09833 T265_09734 T265_09734 T265_08412 T265_08412 T265_14864 T265_14864 T265_14828 T265_14828 T265_10921 T265_10921 T265_14303 T265_14303 T265_07453 T265_07453 T265_07434 T265_07434 T265_07244 T265_07244 T265_14216 T265_14216 T265_10258 T265_10258 T265_07053 T265_07053 T265_06784 T265_06784 T265_14113 T265_14113 T265_06756 T265_06756 T265_09719 T265_09719 T265_06414 T265_06414 T265_06498 T265_06498 T265_06376 T265_06376 T265_06475 T265_06475 MED19 MED19 T265_06290 T265_06290 T265_09316 T265_09316 T265_09179 T265_09179 T265_07176 T265_07176 T265_14195 T265_14195 T265_05761 T265_05761 T265_05839 T265_05839 T265_05533 T265_05533 T265_05387 T265_05387 T265_08404 T265_08404 T265_08379 T265_08379 T265_06471 T265_06471 T265_06436 T265_06436 T265_04737 T265_04737 T265_04351 T265_04351 T265_13470 T265_13470 T265_04996 T265_04996 T265_13633 T265_13633 T265_14134 T265_14134 T265_03768 T265_03768 T265_13585 T265_13585 T265_13303 T265_13303 T265_03334 T265_03334 T265_14015 T265_14015 T265_06297 T265_06297 T265_04366 T265_04366 T265_06123 T265_06123 T265_13439 T265_13439 MED20 MED20 T265_02597 T265_02597 T265_02659 T265_02659 T265_03710 T265_03710 T265_05699 T265_05699 T265_03681 T265_03681 T265_02633 T265_02633 T265_05526 T265_05526 T265_13266 T265_13266 MED11 MED11 T265_15465 T265_15465 T265_15386 T265_15386 MED6 MED6 T265_01621 T265_01621 T265_00965 T265_00965 T265_04180 T265_04180 T265_10570 T265_10570 T265_10407 T265_10407 T265_03911 T265_03911 T265_00433 T265_00433 T265_10220 T265_10220 T265_00759 T265_00759 T265_12509 T265_12509 T265_01404 T265_01404 T265_03591 T265_03591 T265_00098 T265_00098 T265_09760 T265_09760 T265_13195 T265_13195 T265_03123 T265_03123 T265_02614 T265_02614 T265_12508 T265_12508 T265_12992 T265_12992 T265_02389 T265_02389 T265_02353 T265_02353 T265_14681 T265_14681 T265_00138 T265_00138 T265_08613 T265_08613 T265_14619 T265_14619 T265_08087 T265_08087 T265_14474 T265_14474 T265_08010 T265_08010 T265_07978 T265_07978 T265_14412 T265_14412 T265_07669 T265_07669 T265_12507 T265_12507 MED4 MED4 T265_06296 T265_06296 T265_13991 T265_13991 T265_05686 T265_05686 MED8 MED8 T265_12826 T265_12826 T265_12794 T265_12794 T265_12562 T265_12562 T265_00261 T265_00261 T265_00004 T265_00004
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
T265_15656Uncharacterized protein. (1190 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (163 aa)
T265_11575Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (402 aa)
T265_16169EAF domain-containing protein. (86 aa)
T265_10741WD_REPEATS_REGION domain-containing protein. (727 aa)
T265_10596Uncharacterized protein. (429 aa)
T265_15460FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (755 aa)
T265_11289Uncharacterized protein. (263 aa)
T265_15357Uncharacterized protein. (423 aa)
T265_10984Uncharacterized protein. (2803 aa)
T265_16012Uncharacterized protein. (106 aa)
T265_10740Uncharacterized protein. (76 aa)
T265_15236Uncharacterized protein. (115 aa)
T265_10348Med12 domain-containing protein. (2577 aa)
T265_10272Uncharacterized protein; Belongs to the cyclin family. (620 aa)
T265_10196Uncharacterized protein. (185 aa)
T265_10164Uncharacterized protein. (219 aa)
T265_08806TFIIS N-terminal domain-containing protein. (607 aa)
T265_08694Plus3 domain-containing protein. (828 aa)
T265_09892Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (145 aa)
T265_09833WD_REPEATS_REGION domain-containing protein. (1255 aa)
T265_09734Uncharacterized protein. (179 aa)
T265_08412Uncharacterized protein. (275 aa)
T265_14864Uncharacterized protein. (264 aa)
T265_14828HTH TFE/IIEalpha-type domain-containing protein. (431 aa)
T265_10921Uncharacterized protein. (184 aa)
T265_14303Uncharacterized protein. (2198 aa)
T265_07453Uncharacterized protein. (253 aa)
T265_07434Uncharacterized protein. (145 aa)
T265_07244Uncharacterized protein. (1454 aa)
T265_14216CID domain-containing protein. (1149 aa)
T265_10258EAF domain-containing protein. (289 aa)
T265_07053Uncharacterized protein. (1228 aa)
T265_06784Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1571 aa)
T265_14113Reverse transcriptase domain-containing protein. (1401 aa)
T265_06756General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (547 aa)
T265_09719TPR_REGION domain-containing protein. (1256 aa)
T265_06414Uncharacterized protein. (377 aa)
T265_06498Uncharacterized protein. (825 aa)
T265_06376Uncharacterized protein. (297 aa)
T265_06475Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (664 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (427 aa)
T265_06290Uncharacterized protein. (763 aa)
T265_09316Uncharacterized protein. (498 aa)
T265_09179RPOL4c domain-containing protein. (260 aa)
T265_07176Uncharacterized protein. (204 aa)
T265_14195Uncharacterized protein. (938 aa)
T265_05761Uncharacterized protein. (199 aa)
T265_05839Uncharacterized protein. (622 aa)
T265_05533Uncharacterized protein. (766 aa)
T265_05387Uncharacterized protein. (233 aa)
T265_08404acidPPc domain-containing protein. (698 aa)
T265_08379Uncharacterized protein. (216 aa)
T265_06471Uncharacterized protein. (499 aa)
T265_06436Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1722 aa)
T265_04737Uncharacterized protein. (560 aa)
T265_04351Uncharacterized protein. (642 aa)
T265_13470FCP1 homology domain-containing protein. (390 aa)
T265_04996Integrase catalytic domain-containing protein. (972 aa)
T265_13633Uncharacterized protein. (2907 aa)
T265_14134Uncharacterized protein. (282 aa)
T265_03768Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (398 aa)
T265_13585Uncharacterized protein. (496 aa)
T265_13303Uncharacterized protein. (220 aa)
T265_03334Protein kinase domain-containing protein. (433 aa)
T265_14015Uncharacterized protein. (1343 aa)
T265_06297Uncharacterized protein. (1436 aa)
T265_04366TAFH domain-containing protein. (725 aa)
T265_06123Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
T265_13439Uncharacterized protein. (883 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (280 aa)
T265_02597Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
T265_02659Uncharacterized protein. (379 aa)
T265_03710Cyclin_C domain-containing protein; Belongs to the cyclin family. (218 aa)
T265_05699RPOLD domain-containing protein. (640 aa)
T265_03681Cyclin N-terminal domain-containing protein. (516 aa)
T265_02633Uncharacterized protein. (119 aa)
T265_05526Uncharacterized protein. (84 aa)
T265_13266Uncharacterized protein. (667 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (115 aa)
T265_15465mRNA cap 0 methyltransferase domain-containing protein. (386 aa)
T265_15386MAT1 domain-containing protein. (1203 aa)
MED6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (280 aa)
T265_01621TAFII55_N domain-containing protein. (462 aa)
T265_00965TFIIS N-terminal domain-containing protein. (575 aa)
T265_04180Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (295 aa)
T265_10570Uncharacterized protein. (416 aa)
T265_10407DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (103 aa)
T265_03911Uncharacterized protein. (119 aa)
T265_00433Uncharacterized protein. (232 aa)
T265_10220Uncharacterized protein. (840 aa)
T265_00759Uncharacterized protein. (202 aa)
T265_12509Uncharacterized protein. (417 aa)
T265_01404TAFII28 domain-containing protein. (277 aa)
T265_03591Uncharacterized protein. (331 aa)
T265_00098Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2405 aa)
T265_09760Protein kinase domain-containing protein. (888 aa)
T265_13195FMN_red domain-containing protein. (786 aa)
T265_03123Uncharacterized protein. (336 aa)
T265_02614Uncharacterized protein. (2130 aa)
T265_12508Uncharacterized protein. (443 aa)
T265_12992S1 motif domain-containing protein. (1004 aa)
T265_02389Uncharacterized protein. (128 aa)
T265_02353Uncharacterized protein. (370 aa)
T265_14681Uncharacterized protein. (117 aa)
T265_00138Helicase ATP-binding domain-containing protein. (846 aa)
T265_08613Uncharacterized protein. (618 aa)
T265_14619Uncharacterized protein. (266 aa)
T265_08087Uncharacterized protein. (167 aa)
T265_14474Protein kinase domain-containing protein. (1185 aa)
T265_08010CDC73_N domain-containing protein. (501 aa)
T265_07978Med1 domain-containing protein. (1918 aa)
T265_14412TFIID_20kDa domain-containing protein. (473 aa)
T265_07669Uncharacterized protein. (309 aa)
T265_12507PHD-type domain-containing protein. (758 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (407 aa)
T265_06296Uncharacterized protein. (628 aa)
T265_13991DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1203 aa)
T265_05686Uncharacterized protein. (214 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (476 aa)
T265_12826Uncharacterized protein. (1076 aa)
T265_12794RNA_pol_L_2 domain-containing protein. (267 aa)
T265_12562Uncharacterized protein. (108 aa)
T265_00261Uncharacterized protein. (931 aa)
T265_00004DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1846 aa)
Your Current Organism:
Opisthorchis viverrini
NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke
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