(16 nodes) RNA polymerase II, core complex, and Cdc73/Paf1 complex network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_15460	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (755 aa)
	T265_08694	Plus3 domain-containing protein. (828 aa)
	T265_09833	WD_REPEATS_REGION domain-containing protein. (1255 aa)
	T265_09719	TPR_REGION domain-containing protein. (1256 aa)
	T265_09179	RPOL4c domain-containing protein. (260 aa)
	T265_04351	Uncharacterized protein. (642 aa)
	T265_13585	Uncharacterized protein. (496 aa)
	T265_06123	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
	T265_05699	RPOLD domain-containing protein. (640 aa)
	T265_10570	Uncharacterized protein. (416 aa)
	T265_10407	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (103 aa)
	T265_00433	Uncharacterized protein. (232 aa)
	T265_08010	CDC73_N domain-containing protein. (501 aa)
	T265_13991	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1203 aa)
	T265_12826	Uncharacterized protein. (1076 aa)
	T265_12794	RNA_pol_L_2 domain-containing protein. (267 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00433	T265_04351	A0A075A221	A0A074ZP35	Uncharacterized protein.	Uncharacterized protein.	0.969
T265_00433	T265_05699	A0A075A221	A0A074ZV44	Uncharacterized protein.	RPOLD domain-containing protein.	0.999
T265_00433	T265_06123	A0A075A221	A0A074ZTJ6	Uncharacterized protein.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.998
T265_00433	T265_08010	A0A075A221	A0A075A9R3	Uncharacterized protein.	CDC73_N domain-containing protein.	0.856
T265_00433	T265_08694	A0A075A221	A0A074Z885	Uncharacterized protein.	Plus3 domain-containing protein.	0.861
T265_00433	T265_09179	A0A075A221	A0A074ZHS0	Uncharacterized protein.	RPOL4c domain-containing protein.	0.999
T265_00433	T265_09719	A0A075A221	A0A074ZFT5	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.905
T265_00433	T265_09833	A0A075A221	A0A074Z8Q2	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.998
T265_00433	T265_10407	A0A075A221	A0A075A1G3	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.999
T265_00433	T265_10570	A0A075A221	A0A075A0T3	Uncharacterized protein.	Uncharacterized protein.	0.969
T265_00433	T265_12794	A0A075A221	A0A075AJ09	Uncharacterized protein.	RNA_pol_L_2 domain-containing protein.	0.999
T265_00433	T265_12826	A0A075A221	A0A075AIU2	Uncharacterized protein.	Uncharacterized protein.	0.953
T265_00433	T265_13585	A0A075A221	A0A074ZRH7	Uncharacterized protein.	Uncharacterized protein.	0.993
T265_00433	T265_13991	A0A075A221	A0A075AE14	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
T265_00433	T265_15460	A0A075A221	A0A074Z2M3	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.949
T265_04351	T265_00433	A0A074ZP35	A0A075A221	Uncharacterized protein.	Uncharacterized protein.	0.969
T265_04351	T265_05699	A0A074ZP35	A0A074ZV44	Uncharacterized protein.	RPOLD domain-containing protein.	0.997
T265_04351	T265_06123	A0A074ZP35	A0A074ZTJ6	Uncharacterized protein.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.973
T265_04351	T265_08010	A0A074ZP35	A0A075A9R3	Uncharacterized protein.	CDC73_N domain-containing protein.	0.801
T265_04351	T265_08694	A0A074ZP35	A0A074Z885	Uncharacterized protein.	Plus3 domain-containing protein.	0.815