(86 nodes) Mixed, incl. Glutathione metabolism, and Metallopeptidase activity network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_16334	Peptidase_M3 domain-containing protein. (76 aa)
	T265_15991	Uncharacterized protein. (105 aa)
	T265_15493	Hexosyltransferase. (366 aa)
	T265_16215	Uncharacterized protein. (182 aa)
	T265_11166	Peptidase_M3 domain-containing protein. (727 aa)
	T265_15775	Peptidase_M13_N domain-containing protein. (375 aa)
	T265_10528	Integrase catalytic domain-containing protein. (580 aa)
	T265_09745	SH2 domain-containing protein. (1080 aa)
	T265_16112	Uncharacterized protein. (91 aa)
	T265_09672	Aminopeptidase. (910 aa)
	T265_08944	SAM domain-containing protein. (613 aa)
	T265_15062	Hexosyltransferase. (439 aa)
	T265_08955	Uncharacterized protein. (197 aa)
	T265_08677	Hexosyltransferase. (420 aa)
	T265_08585	Peptidase_M3 domain-containing protein. (970 aa)
	T265_08267	HMG box domain-containing protein. (1020 aa)
	T265_09337	Dipeptidyl peptidase 3; Belongs to the peptidase M49 family. (731 aa)
	T265_09164	Uncharacterized protein. (208 aa)
	T265_07894	Uncharacterized protein. (110 aa)
	T265_07747	Hexosyltransferase. (422 aa)
	T265_07893	Uncharacterized protein. (144 aa)
	T265_09078	Uncharacterized protein. (705 aa)
	T265_08870	CYTOSOL_AP domain-containing protein. (599 aa)
	T265_08710	Uncharacterized protein. (714 aa)
	T265_06739	Pyroglutamyl-peptidase I. (229 aa)
	T265_08414	TPT domain-containing protein. (369 aa)
	T265_14492	Uncharacterized protein. (494 aa)
	T265_04879	Uncharacterized protein. (746 aa)
	T265_05555	Uncharacterized protein. (980 aa)
	T265_05570	Uncharacterized protein. (694 aa)
	T265_04514	Uncharacterized protein. (227 aa)
	T265_05510	DSBA domain-containing protein. (361 aa)
	T265_13386	Peptidase C83 domain-containing protein. (546 aa)
	T265_04051	Uncharacterized protein; Belongs to the peptidase M16 family. (987 aa)
	T265_03276	Uncharacterized protein. (294 aa)
	T265_16204	Uncharacterized protein. (69 aa)
	T265_04390	M16C_associated domain-containing protein. (832 aa)
	T265_03085	Uncharacterized protein. (461 aa)
	T265_02296	Uncharacterized protein. (210 aa)
	T265_02042	Uncharacterized protein. (843 aa)
	T265_02191	AAA domain-containing protein. (1191 aa)
	T265_01991	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (141 aa)
	T265_04937	Uncharacterized protein. (430 aa)
	T265_01797	Glutathione synthetase. (442 aa)
	T265_13029	Uncharacterized protein. (335 aa)
	T265_01213	DUF89 domain-containing protein. (492 aa)
	T265_00846	Uncharacterized protein; Belongs to the GST superfamily. (191 aa)
	T265_02066	Cysteine dioxygenase. (228 aa)
	T265_10643	Uncharacterized protein. (322 aa)
	T265_04264	Uncharacterized protein. (252 aa)
	T265_01195	GST N-terminal domain-containing protein; Belongs to the GST superfamily. (265 aa)
	T265_01990	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (345 aa)
	T265_01660	Uncharacterized protein; Belongs to the GST superfamily. (253 aa)
	T265_10225	Uncharacterized protein. (132 aa)
	T265_01536	KH domain-containing protein. (597 aa)
	T265_09865	Uncharacterized protein. (1162 aa)
	T265_00033	Uncharacterized protein. (1227 aa)
	T265_12521	Uncharacterized protein. (836 aa)
	T265_14959	Uncharacterized protein. (467 aa)
	T265_13210	Uncharacterized protein. (593 aa)
	T265_00845	Uncharacterized protein; Belongs to the GST superfamily. (208 aa)
	T265_14888	Uncharacterized protein; Belongs to the GST superfamily. (310 aa)
	T265_00162	Uncharacterized protein. (446 aa)
	T265_09223	Uncharacterized protein. (800 aa)
	T265_02526	Uncharacterized protein. (396 aa)
	T265_13016	Uncharacterized protein. (400 aa)
	T265_02427	Uncharacterized protein. (1332 aa)
	T265_02259	Uncharacterized protein. (177 aa)
	T265_00164	DFP domain-containing protein. (429 aa)
	T265_08117	AMP_N domain-containing protein. (504 aa)
	T265_07895	Putative ATP synthase F0, A subunit. (382 aa)
	T265_12599	Peptidase_M13_N domain-containing protein. (247 aa)
	T265_05966	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (377 aa)
	T265_03902	CYTOSOL_AP domain-containing protein. (479 aa)
	T265_03860	Uncharacterized protein. (349 aa)
	T265_03688	Uncharacterized protein; Belongs to the GST superfamily. (244 aa)
	T265_03218	DUF89 domain-containing protein. (883 aa)
	T265_12838	Uncharacterized protein. (1038 aa)
	T265_01223	Uncharacterized protein. (397 aa)
	T265_00847	Uncharacterized protein. (210 aa)
	T265_00656	ACPS domain-containing protein. (260 aa)
	T265_12598	Uncharacterized protein. (171 aa)
	T265_00311	Helix-loop-helix DNA-binding domain protein. (411 aa)
	T265_00014	Glutamate-cysteine ligase, catalytic subunit. (704 aa)
	T265_00029	Uncharacterized protein. (1130 aa)
	T265_00160	Uncharacterized protein. (1229 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00014	T265_00033	A0A075AJX3	A0A075A3D3	Glutamate-cysteine ligase, catalytic subunit.	Uncharacterized protein.	0.946
T265_00014	T265_01195	A0A075AJX3	A0A075A0N4	Glutamate-cysteine ligase, catalytic subunit.	GST N-terminal domain-containing protein; Belongs to the GST superfamily.	0.514
T265_00014	T265_01797	A0A075AJX3	A0A074ZY53	Glutamate-cysteine ligase, catalytic subunit.	Glutathione synthetase.	0.992
T265_00014	T265_02066	A0A075AJX3	A0A075A0D4	Glutamate-cysteine ligase, catalytic subunit.	Cysteine dioxygenase.	0.802
T265_00014	T265_03902	A0A075AJX3	A0A075AH76	Glutamate-cysteine ligase, catalytic subunit.	CYTOSOL_AP domain-containing protein.	0.900
T265_00014	T265_08267	A0A075AJX3	A0A074Z9R1	Glutamate-cysteine ligase, catalytic subunit.	HMG box domain-containing protein.	0.900
T265_00014	T265_08870	A0A075AJX3	A0A074ZIN2	Glutamate-cysteine ligase, catalytic subunit.	CYTOSOL_AP domain-containing protein.	0.900
T265_00014	T265_09223	A0A075AJX3	A0A075A5Q4	Glutamate-cysteine ligase, catalytic subunit.	Uncharacterized protein.	0.933
T265_00014	T265_10528	A0A075AJX3	A0A074Z245	Glutamate-cysteine ligase, catalytic subunit.	Integrase catalytic domain-containing protein.	0.930
T265_00029	T265_04390	A0A075AJX8	A0A074ZSP0	Uncharacterized protein.	M16C_associated domain-containing protein.	0.488
T265_00029	T265_04937	A0A075AJX8	A0A074ZY11	Uncharacterized protein.	Uncharacterized protein.	0.421
T265_00029	T265_07893	A0A075AJX8	A0A074ZFP9	Uncharacterized protein.	Uncharacterized protein.	0.421
T265_00029	T265_07894	A0A075AJX8	A0A074ZBG4	Uncharacterized protein.	Uncharacterized protein.	0.421
T265_00029	T265_07895	A0A075AJX8	A0A075AA72	Uncharacterized protein.	Putative ATP synthase F0, A subunit.	0.421
T265_00029	T265_08117	A0A075AJX8	A0A075A9E3	Uncharacterized protein.	AMP_N domain-containing protein.	0.512
T265_00029	T265_08414	A0A075AJX8	A0A074ZK78	Uncharacterized protein.	TPT domain-containing protein.	0.416
T265_00029	T265_08944	A0A075AJX8	A0A074Z7K1	Uncharacterized protein.	SAM domain-containing protein.	0.651
T265_00029	T265_09337	A0A075AJX8	A0A074ZAP3	Uncharacterized protein.	Dipeptidyl peptidase 3; Belongs to the peptidase M49 family.	0.564
T265_00029	T265_16215	A0A075AJX8	A0A074YYF4	Uncharacterized protein.	Uncharacterized protein.	0.421
T265_00033	T265_00014	A0A075A3D3	A0A075AJX3	Uncharacterized protein.	Glutamate-cysteine ligase, catalytic subunit.	0.946