(152 nodes) Neddylation, and Ubiquitin conjugating enzyme activity network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_12331	Uncharacterized protein. (177 aa)
	T265_16205	Uncharacterized protein. (72 aa)
	T265_11722	Uncharacterized protein. (204 aa)
	T265_11750	Uncharacterized protein. (1518 aa)
	T265_15506	CULLIN_2 domain-containing protein; Belongs to the cullin family. (810 aa)
	T265_11456	Uncharacterized protein. (201 aa)
	T265_11323	Proteasome subunit beta; Belongs to the peptidase T1B family. (224 aa)
	T265_16033	B box-type domain-containing protein. (95 aa)
	T265_12207	Uncharacterized protein. (133 aa)
	T265_15267	UBIQUITIN_CONJUGAT_2 domain-containing protein. (192 aa)
	T265_10450	UBIQUITIN_CONJUGAT_2 domain-containing protein. (283 aa)
	T265_11291	UBA domain-containing protein. (237 aa)
	T265_15031	ANK_REP_REGION domain-containing protein. (201 aa)
	T265_11222	RBR-type E3 ubiquitin transferase. (511 aa)
	T265_16265	Uncharacterized protein. (105 aa)
	T265_14958	TPR_REGION domain-containing protein. (294 aa)
	T265_14949	Uncharacterized protein. (540 aa)
	T265_09744	Uncharacterized protein. (202 aa)
	T265_16091	Uncharacterized protein. (111 aa)
	T265_15978	RPN1_C domain-containing protein. (169 aa)
	T265_12114	Proteasome subunit alpha type. (235 aa)
	T265_09096	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (245 aa)
	T265_09064	Proteasome subunit alpha type. (263 aa)
	T265_10137	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (214 aa)
	T265_10119	Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (282 aa)
	T265_11768	PCI domain-containing protein. (759 aa)
	T265_14640	Mov34/MPN/PAD-1 family protein. (404 aa)
	T265_08645	AAA domain-containing protein; Belongs to the AAA ATPase family. (623 aa)
	T265_08644	Uncharacterized protein. (1319 aa)
	T265_08544	WD_REPEATS_REGION domain-containing protein. (860 aa)
	T265_09797	U-box domain-containing protein. (151 aa)
	T265_08481	Uncharacterized protein. (654 aa)
	T265_08487	UBA_e1_C domain-containing protein. (1281 aa)
	T265_08464	Uncharacterized protein. (846 aa)
	T265_15436	Proteasome endopeptidase complex. (266 aa)
	T265_09675	Uncharacterized protein. (244 aa)
	T265_14512	Uncharacterized protein. (472 aa)
	T265_14855	Ubiquitin--protein ligase; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	T265_10909	UBIQUITIN_CONJUGAT_2 domain-containing protein. (1138 aa)
	T265_07637	CSN8_PSD8_EIF3K domain-containing protein. (118 aa)
	T265_07486	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (574 aa)
	T265_08762	UBIQUITIN_CONJUGAT_2 domain-containing protein. (138 aa)
	T265_07388	UBA_e1_C domain-containing protein. (1426 aa)
	T265_07359	Ubiquitin family protein. (152 aa)
	T265_07002	U-box domain-containing protein. (340 aa)
	T265_08189	UBIQUITIN_CONJUGAT_2 domain-containing protein. (162 aa)
	T265_06916	Uncharacterized protein. (1133 aa)
	T265_14156	Uncharacterized protein. (118 aa)
	T265_10021	RBR-type E3 ubiquitin transferase. (530 aa)
	T265_09824	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (980 aa)
	T265_06504	Ubiquitin--protein ligase. (162 aa)
	T265_14049	RING-type domain-containing protein. (257 aa)
	T265_06384	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (397 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (612 aa)
	T265_07590	PCI domain-containing protein. (279 aa)
	T265_14846	UBIQUITIN_CONJUGAT_2 domain-containing protein. (102 aa)
	T265_07459	UCH_C domain-containing protein. (110 aa)
	T265_06012	Uncharacterized protein. (170 aa)
	T265_14197	OTU domain-containing protein. (291 aa)
	T265_05863	Protein kinase domain-containing protein. (977 aa)
	T265_07046	UBIQUITIN_CONJUGAT_2 domain-containing protein. (638 aa)
	T265_14143	RPN13_C domain-containing protein. (440 aa)
	T265_06687	Uncharacterized protein. (1701 aa)
	T265_05172	HECT domain-containing protein. (1156 aa)
	T265_14511	CSN8_PSD8_EIF3K domain-containing protein. (211 aa)
	T265_13711	Uncharacterized protein. (508 aa)
	T265_08061	Uncharacterized protein. (1267 aa)
	T265_07767	Ubiquitin carboxyl-terminal hydrolase. (533 aa)
	T265_07694	ANK_REP_REGION domain-containing protein. (239 aa)
	T265_05680	BTB domain-containing protein. (1285 aa)
	T265_13821	Uncharacterized protein. (324 aa)
	T265_07477	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (273 aa)
	T265_07452	UBIQUITIN_CONJUGAT_2 domain-containing protein. (670 aa)
	T265_04038	Ubiquitin--protein ligase; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
	T265_07049	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	T265_07009	ULP_PROTEASE domain-containing protein. (217 aa)
	T265_04024	Ubiquitin--protein ligase. (582 aa)
	T265_03776	Uncharacterized protein. (299 aa)
	T265_04792	CULLIN_2 domain-containing protein; Belongs to the cullin family. (894 aa)
	T265_03610	Zinc finger, C3HC4 type. (279 aa)
	T265_13278	Ubiquitin family protein. (274 aa)
	T265_03303	MPN domain-containing protein. (431 aa)
	T265_13180	Uncharacterized protein. (218 aa)
	T265_06273	Reverse transcriptase domain-containing protein. (2795 aa)
	T265_06292	Protein kinase domain-containing protein. (479 aa)
	T265_13205	AAA domain-containing protein; Belongs to the AAA ATPase family. (426 aa)
	T265_04298	CULLIN_2 domain-containing protein; Belongs to the cullin family. (737 aa)
	T265_03237	PA28_beta domain-containing protein. (288 aa)
	T265_12451	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (156 aa)
	T265_16002	Uncharacterized protein. (142 aa)
	T265_13406	PCI domain-containing protein. (451 aa)
	T265_03830	ThiF domain-containing protein. (674 aa)
	T265_03558	Ubiquitin-like domain-containing protein. (80 aa)
	T265_02501	Uncharacterized protein. (1045 aa)
	T265_02379	PCI domain-containing protein. (430 aa)
	T265_05368	Uncharacterized protein. (389 aa)
	T265_01982	AAA domain-containing protein; Belongs to the AAA ATPase family. (386 aa)
	T265_11448	PCI domain-containing protein. (434 aa)
	T265_01886	PCI domain protein. (445 aa)
	T265_04891	Uncharacterized protein. (357 aa)
	T265_15392	Uncharacterized protein. (813 aa)
	T265_01606	RBR-type E3 ubiquitin transferase. (769 aa)
	T265_01440	RBR-type E3 ubiquitin transferase. (369 aa)
	T265_13047	Uncharacterized protein. (209 aa)
	T265_11016	TIP120 domain-containing protein. (1499 aa)
	T265_11006	UBIQUITIN_CONJUGAT_2 domain-containing protein. (282 aa)
	T265_02414	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (162 aa)
	T265_10835	Uncharacterized protein. (142 aa)
	T265_01323	CULLIN_2 domain-containing protein; Belongs to the cullin family. (966 aa)
	T265_10770	Uncharacterized protein. (570 aa)
	T265_04245	MATH domain protein. (546 aa)
	T265_10611	AAA domain-containing protein; Belongs to the AAA ATPase family. (442 aa)
	T265_01934	CPSF_A domain-containing protein. (1330 aa)
	T265_10549	HECT domain-containing protein. (3250 aa)
	T265_00599	Ubiquitin carboxyl-terminal hydrolase. (219 aa)
	T265_00660	VWFA domain-containing protein. (512 aa)
	T265_03926	Uncharacterized protein. (322 aa)
	T265_13365	PCI domain protein. (437 aa)
	T265_00810	PCI domain-containing protein. (503 aa)
	T265_10217	AAA domain-containing protein; Belongs to the AAA ATPase family. (292 aa)
	T265_10121	Mov34/MPN/PAD-1 family protein. (344 aa)
	T265_03572	Proteasome subunit alpha type. (247 aa)
	T265_15032	Uncharacterized protein. (790 aa)
	T265_01222	Uncharacterized protein. (172 aa)
	T265_13254	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2824 aa)
	T265_09727	Uncharacterized protein. (197 aa)
	T265_03078	PCI domain-containing protein. (451 aa)
	T265_00626	Zf-rbx1 domain-containing protein. (332 aa)
	T265_00543	Uncharacterized protein. (476 aa)
	T265_00291	UBIQUITIN_CONJUGAT_2 domain-containing protein. (304 aa)
	T265_00388	Uncharacterized protein. (420 aa)
	T265_08989	Ubiquitin--protein ligase; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
	T265_12982	Uncharacterized protein. (2575 aa)
	T265_08813	AAA domain-containing protein; Belongs to the AAA ATPase family. (417 aa)
	T265_08665	Ubiquitin-like domain-containing protein. (140 aa)
	T265_08127	Rhodanese domain-containing protein. (961 aa)
	T265_01373	Proteasome subunit beta. (282 aa)
	T265_14376	Thioredoxin. (97 aa)
	T265_14359	Uncharacterized protein. (3872 aa)
	T265_07360	Uncharacterized protein. (456 aa)
	T265_00546	Uncharacterized protein. (421 aa)
	T265_06105	Uncharacterized protein. (217 aa)
	T265_05436	RING-type domain-containing protein. (694 aa)
	T265_13718	UBIQUITIN_CONJUGAT_2 domain-containing protein. (5372 aa)
	T265_13591	Uncharacterized protein. (256 aa)
	T265_04415	Uncharacterized protein. (303 aa)
	T265_13346	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (451 aa)
	T265_02496	Proteasome maturation factor UMP1. (144 aa)
	T265_02133	Ubiquitin-like domain-containing protein. (804 aa)
	T265_02099	Uncharacterized protein. (976 aa)
	T265_12882	F-box domain-containing protein. (534 aa)
	T265_00468	MPN domain-containing protein. (1771 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KATNAL2	T265_00388	A0A074ZGH5	A0A075A6G6	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Uncharacterized protein.	0.472
KATNAL2	T265_00468	A0A074ZGH5	A0A075AJQ7	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	MPN domain-containing protein.	0.853
KATNAL2	T265_00543	A0A074ZGH5	A0A075A5V4	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Uncharacterized protein.	0.813
KATNAL2	T265_00546	A0A074ZGH5	A0A075ACM6	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Uncharacterized protein.	0.813
KATNAL2	T265_00626	A0A074ZGH5	A0A075A5D8	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Zf-rbx1 domain-containing protein.	0.725
KATNAL2	T265_00660	A0A074ZGH5	A0A075A1E4	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	VWFA domain-containing protein.	0.995
KATNAL2	T265_00810	A0A074ZGH5	A0A075A1S0	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	PCI domain-containing protein.	0.919
KATNAL2	T265_01222	A0A074ZGH5	A0A075A3B3	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Uncharacterized protein.	0.851
KATNAL2	T265_01323	A0A074ZGH5	A0A074ZZY9	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.961
KATNAL2	T265_01373	A0A074ZGH5	A0A075AAC7	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Proteasome subunit beta.	0.851
KATNAL2	T265_01982	A0A074ZGH5	A0A074ZWR2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.895
KATNAL2	T265_02099	A0A074ZGH5	A0A075AIJ3	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Uncharacterized protein.	0.968
KATNAL2	T265_02133	A0A074ZGH5	A0A075AIH0	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Ubiquitin-like domain-containing protein.	0.920
KATNAL2	T265_02379	A0A074ZGH5	A0A074ZW28	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	PCI domain-containing protein.	0.999
KATNAL2	T265_02414	A0A074ZGH5	A0A074ZZD1	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.472
KATNAL2	T265_03078	A0A074ZGH5	A0A075A4F1	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	PCI domain-containing protein.	0.992
KATNAL2	T265_03237	A0A074ZGH5	A0A074ZT50	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	PA28_beta domain-containing protein.	0.649
KATNAL2	T265_03303	A0A074ZGH5	A0A074ZS62	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	MPN domain-containing protein.	0.853
KATNAL2	T265_03558	A0A074ZGH5	A0A074ZVF5	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Ubiquitin-like domain-containing protein.	0.868
KATNAL2	T265_03572	A0A074ZGH5	A0A075A2S1	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	Proteasome subunit alpha type.	0.851