(43 nodes) Structural constituent of chromatin, and ESC/E(Z) complex network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_12402	Histone H2B; Belongs to the histone H2B family. (64 aa)
	T265_12280	Uncharacterized protein. (98 aa)
	T265_03554	Histone H2B; Belongs to the histone H2B family. (122 aa)
	T265_15522	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
	T265_11051	Uncharacterized protein. (295 aa)
	T265_11922	Uncharacterized protein. (1453 aa)
	T265_14970	Hat1_N domain-containing protein. (438 aa)
	T265_11049	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)
	T265_10344	SET domain protein. (1792 aa)
	T265_09018	Uncharacterized protein. (87 aa)
	T265_08808	Uncharacterized protein. (1587 aa)
	T265_14664	WW domain-containing protein. (839 aa)
	T265_09632	VEFS-Box domain-containing protein. (1163 aa)
	T265_11408	Histone H2A; Belongs to the histone H2A family. (82 aa)
	T265_14800	Uncharacterized protein. (495 aa)
	T265_09887	Histone H2A; Belongs to the histone H2A family. (99 aa)
	T265_14033	C2H2-type domain-containing protein. (517 aa)
	T265_13914	Histone domain-containing protein. (240 aa)
	T265_05708	Histone H2A; Belongs to the histone H2A family. (125 aa)
	T265_13785	Uncharacterized protein. (1593 aa)
	T265_05767	WD_REPEATS_REGION domain-containing protein. (473 aa)
	T265_05406	H15 domain-containing protein. (356 aa)
	T265_08152	Histone H2A; Belongs to the histone H2A family. (157 aa)
	T265_05015	Histone H2A; Belongs to the histone H2A family. (134 aa)
	T265_05840	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	T265_07277	WD_REPEATS_REGION domain-containing protein. (561 aa)
	T265_04602	BAH domain-containing protein. (2687 aa)
	T265_12259	Uncharacterized protein. (120 aa)
	T265_04197	Histone H2A; Belongs to the histone H2A family. (125 aa)
	T265_02926	WD_REPEATS_REGION domain-containing protein. (416 aa)
	T265_05710	Uncharacterized protein. (137 aa)
	T265_03691	Uncharacterized protein. (198 aa)
	T265_12418	Histone H2A; Belongs to the histone H2A family. (187 aa)
	T265_13221	Histone H3; Belongs to the histone H3 family. (136 aa)
	T265_01084	Histone domain-containing protein. (72 aa)
	T265_09395	SHNi-TPR domain-containing protein. (441 aa)
	T265_01844	Histone domain-containing protein. (287 aa)
	T265_07302	PHD-type domain-containing protein. (384 aa)
	T265_05828	Core histone H2A/H2B/H3/H4; Belongs to the histone H2B family. (108 aa)
	T265_05709	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (172 aa)
	T265_04783	Linker histone H1 and H5 family protein. (80 aa)
	T265_13347	Uncharacterized protein. (1125 aa)
	T265_00193	Uncharacterized protein. (1029 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00193	T265_01084	A0A075AJU5	A0A075A3Z1	Uncharacterized protein.	Histone domain-containing protein.	0.621
T265_00193	T265_01844	A0A075AJU5	A0A075A8L9	Uncharacterized protein.	Histone domain-containing protein.	0.621
T265_00193	T265_03554	A0A075AJU5	A0A074YVS2	Uncharacterized protein.	Histone H2B; Belongs to the histone H2B family.	0.408
T265_00193	T265_03691	A0A075AJU5	A0A074ZVA2	Uncharacterized protein.	Uncharacterized protein.	0.599
T265_00193	T265_05406	A0A075AJU5	A0A074ZJS2	Uncharacterized protein.	H15 domain-containing protein.	0.423
T265_00193	T265_05709	A0A075AJU5	A0A075AEX9	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.572
T265_00193	T265_05710	A0A075AJU5	A0A074ZUZ6	Uncharacterized protein.	Uncharacterized protein.	0.616
T265_00193	T265_05828	A0A075AJU5	A0A075AEU4	Uncharacterized protein.	Core histone H2A/H2B/H3/H4; Belongs to the histone H2B family.	0.408
T265_00193	T265_05840	A0A075AJU5	A0A074ZML9	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.572
T265_00193	T265_08808	A0A075AJU5	A0A074Z843	Uncharacterized protein.	Uncharacterized protein.	0.558
T265_00193	T265_10344	A0A075AJU5	A0A074Z6V9	Uncharacterized protein.	SET domain protein.	0.494
T265_00193	T265_11049	A0A075AJU5	A0A074Z4F0	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.572
T265_00193	T265_11051	A0A075AJU5	A0A074Z0E4	Uncharacterized protein.	Uncharacterized protein.	0.556
T265_00193	T265_11922	A0A075AJU5	A0A074Z192	Uncharacterized protein.	Uncharacterized protein.	0.568
T265_00193	T265_12402	A0A075AJU5	A0A074YT82	Uncharacterized protein.	Histone H2B; Belongs to the histone H2B family.	0.408
T265_00193	T265_13221	A0A075AJU5	A0A075A3R5	Uncharacterized protein.	Histone H3; Belongs to the histone H3 family.	0.621
T265_00193	T265_13347	A0A075AJU5	A0A075AHA7	Uncharacterized protein.	Uncharacterized protein.	0.453
T265_00193	T265_13785	A0A075AJU5	A0A074ZJK2	Uncharacterized protein.	Uncharacterized protein.	0.453
T265_00193	T265_13914	A0A075AJU5	A0A074ZHX7	Uncharacterized protein.	Histone domain-containing protein.	0.621
T265_00193	T265_14664	A0A075AJU5	A0A074Z887	Uncharacterized protein.	WW domain-containing protein.	0.494