(12 nodes) MAP2K and MAPK activation, and 14-3-3 protein network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_12118	Protein kinase domain-containing protein. (668 aa)
	T265_11052	Uncharacterized protein. (109 aa)
	T265_10821	Ras family protein. (262 aa)
	T265_06616	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (466 aa)
	T265_05786	Uncharacterized protein. (1145 aa)
	T265_07713	Uncharacterized protein. (948 aa)
	T265_13518	Protein kinase domain-containing protein. (538 aa)
	T265_04189	Uncharacterized protein. (812 aa)
	T265_16190	Uncharacterized protein. (44 aa)
	T265_12520	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (326 aa)
	T265_02129	Non-specific serine/threonine protein kinase. (1492 aa)
	T265_00011	Uncharacterized protein. (233 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00011	T265_02129	A0A075AJX1	A0A075AIG9	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.463
T265_00011	T265_04189	A0A075AJX1	A0A074ZPS3	Uncharacterized protein.	Uncharacterized protein.	0.893
T265_00011	T265_05786	A0A075AJX1	A0A074ZMU8	Uncharacterized protein.	Uncharacterized protein.	0.710
T265_00011	T265_06616	A0A075AJX1	A0A074ZFH9	Uncharacterized protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.442
T265_00011	T265_07713	A0A075AJX1	A0A074ZMX3	Uncharacterized protein.	Uncharacterized protein.	0.641
T265_00011	T265_10821	A0A075AJX1	A0A074ZBX2	Uncharacterized protein.	Ras family protein.	0.476
T265_00011	T265_11052	A0A075AJX1	A0A074Z4C9	Uncharacterized protein.	Uncharacterized protein.	0.669
T265_00011	T265_12118	A0A075AJX1	A0A074YW16	Uncharacterized protein.	Protein kinase domain-containing protein.	0.669
T265_00011	T265_12520	A0A075AJX1	A0A075ACY5	Uncharacterized protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.442
T265_00011	T265_13518	A0A075AJX1	A0A074ZN21	Uncharacterized protein.	Protein kinase domain-containing protein.	0.562
T265_02129	T265_00011	A0A075AIG9	A0A075AJX1	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.463
T265_02129	T265_04189	A0A075AIG9	A0A074ZPS3	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.690
T265_02129	T265_05786	A0A075AIG9	A0A074ZMU8	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.799
T265_02129	T265_06616	A0A075AIG9	A0A074ZFH9	Non-specific serine/threonine protein kinase.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.611
T265_02129	T265_07713	A0A075AIG9	A0A074ZMX3	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.694
T265_02129	T265_11052	A0A075AIG9	A0A074Z4C9	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.552
T265_02129	T265_12118	A0A075AIG9	A0A074YW16	Non-specific serine/threonine protein kinase.	Protein kinase domain-containing protein.	0.613
T265_02129	T265_12520	A0A075AIG9	A0A075ACY5	Non-specific serine/threonine protein kinase.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.611
T265_04189	T265_00011	A0A074ZPS3	A0A075AJX1	Uncharacterized protein.	Uncharacterized protein.	0.893
T265_04189	T265_02129	A0A074ZPS3	A0A075AIG9	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.690