(62 nodes) RHO GTPase cycle, and Sarcomere organization network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_16163	Uncharacterized protein. (35 aa)
	T265_15799	Uncharacterized protein. (142 aa)
	T265_11555	Ras family protein. (188 aa)
	T265_11177	Rho-GAP domain-containing protein. (1007 aa)
	T265_10176	Protein kinase domain-containing protein. (862 aa)
	T265_10957	Drf_GBD domain-containing protein. (187 aa)
	T265_12173	Uncharacterized protein. (157 aa)
	T265_09132	Uncharacterized protein. (192 aa)
	T265_10340	Uncharacterized protein. (215 aa)
	T265_08991	Uncharacterized protein. (175 aa)
	T265_08998	Uncharacterized protein. (516 aa)
	T265_10146	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1072 aa)
	T265_08668	Uncharacterized protein. (454 aa)
	T265_11579	SH3 domain-containing protein. (549 aa)
	T265_08398	Uncharacterized protein. (1478 aa)
	T265_14719	Uncharacterized protein. (183 aa)
	T265_10300	DH domain-containing protein. (775 aa)
	T265_08299	Uncharacterized protein. (1142 aa)
	T265_14462	Uncharacterized protein. (1692 aa)
	T265_14978	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1605 aa)
	T265_06660	ELMO domain-containing protein. (1015 aa)
	T265_07788	DUF4537 domain-containing protein. (4213 aa)
	T265_07158	Uncharacterized protein. (324 aa)
	T265_06049	Rho-GAP domain-containing protein. (891 aa)
	T265_05685	Uncharacterized protein. (181 aa)
	T265_08652	Kinase domain protein. (1841 aa)
	T265_08295	Phorbol-ester/DAG-type domain-containing protein. (372 aa)
	T265_13614	Uncharacterized protein. (106 aa)
	T265_04561	G domain-containing protein. (352 aa)
	T265_04520	Uncharacterized protein. (239 aa)
	T265_06868	Uncharacterized protein. (331 aa)
	T265_14129	Protein kinase domain-containing protein. (917 aa)
	T265_04560	Uncharacterized protein. (247 aa)
	T265_06456	Uncharacterized protein. (1383 aa)
	T265_06345	FH2 domain-containing protein. (335 aa)
	T265_03150	Uncharacterized protein. (635 aa)
	T265_03000	Uncharacterized protein. (210 aa)
	T265_03901	Uncharacterized protein; Belongs to the DOCK family. (2088 aa)
	T265_02410	Uncharacterized protein. (326 aa)
	T265_02122	Protein kinase domain-containing protein. (959 aa)
	T265_01552	Uncharacterized protein. (1131 aa)
	T265_02626	Uncharacterized protein. (457 aa)
	T265_02569	Protein kinase domain-containing protein. (2331 aa)
	T265_12835	Ig-like domain-containing protein. (82 aa)
	T265_12535	Protein kinase domain-containing protein. (245 aa)
	T265_00260	Uncharacterized protein. (288 aa)
	T265_03503	Rho-GAP domain-containing protein. (1116 aa)
	T265_03099	Ig-like domain-containing protein. (213 aa)
	T265_03109	Uncharacterized protein. (4297 aa)
	T265_00479	Uncharacterized protein. (2474 aa)
	T265_07465	Actin; Belongs to the actin family. (288 aa)
	T265_14220	Uncharacterized protein. (912 aa)
	T265_06450	Uncharacterized protein. (763 aa)
	T265_06472	Uncharacterized protein. (1097 aa)
	T265_13951	Rho-GAP domain-containing protein. (545 aa)
	T265_13593	PH domain-containing protein. (1193 aa)
	T265_04454	Uncharacterized protein. (909 aa)
	T265_01888	Uncharacterized protein. (698 aa)
	T265_12742	Uncharacterized protein. (1984 aa)
	T265_00829	Uncharacterized protein. (163 aa)
	T265_00684	F-BAR domain-containing protein. (1417 aa)
	T265_12536	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (499 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00260	T265_00479	A0A075A309	A0A075A666	Uncharacterized protein.	Uncharacterized protein.	0.761
T265_00260	T265_00829	A0A075A309	A0A075AJG4	Uncharacterized protein.	Uncharacterized protein.	0.430
T265_00260	T265_01888	A0A075A309	A0A075AIN7	Uncharacterized protein.	Uncharacterized protein.	0.565
T265_00260	T265_02410	A0A075A309	A0A074ZW55	Uncharacterized protein.	Uncharacterized protein.	0.510
T265_00260	T265_03099	A0A075A309	A0A075A4H7	Uncharacterized protein.	Ig-like domain-containing protein.	0.761
T265_00260	T265_03109	A0A075A309	A0A075A4I3	Uncharacterized protein.	Uncharacterized protein.	0.761
T265_00260	T265_03503	A0A075A309	A0A075A370	Uncharacterized protein.	Rho-GAP domain-containing protein.	0.420
T265_00260	T265_03901	A0A075A309	A0A074ZUA8	Uncharacterized protein.	Uncharacterized protein; Belongs to the DOCK family.	0.529
T265_00260	T265_04454	A0A075A309	A0A075AGI7	Uncharacterized protein.	Uncharacterized protein.	0.405
T265_00260	T265_06456	A0A075A309	A0A074ZSC5	Uncharacterized protein.	Uncharacterized protein.	0.466
T265_00260	T265_06868	A0A075A309	A0A074ZR04	Uncharacterized protein.	Uncharacterized protein.	0.447
T265_00260	T265_10146	A0A075A309	A0A074Z7I3	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.466
T265_00260	T265_12835	A0A075A309	A0A074ZYX9	Uncharacterized protein.	Ig-like domain-containing protein.	0.761
T265_00260	T265_14462	A0A075A309	A0A074ZF36	Uncharacterized protein.	Uncharacterized protein.	0.946
T265_00479	T265_00260	A0A075A666	A0A075A309	Uncharacterized protein.	Uncharacterized protein.	0.761
T265_00479	T265_00829	A0A075A666	A0A075AJG4	Uncharacterized protein.	Uncharacterized protein.	0.863
T265_00479	T265_02122	A0A075A666	A0A074ZWD3	Uncharacterized protein.	Protein kinase domain-containing protein.	0.454
T265_00479	T265_03000	A0A075A666	A0A074ZU96	Uncharacterized protein.	Uncharacterized protein.	0.761
T265_00479	T265_03901	A0A075A666	A0A074ZUA8	Uncharacterized protein.	Uncharacterized protein; Belongs to the DOCK family.	0.505
T265_00479	T265_04520	A0A075A666	A0A074ZMX6	Uncharacterized protein.	Uncharacterized protein.	0.863