(14 nodes) Mixed, incl. PI3K events in ERBB2 signaling, and BAR domain network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_09141	E3 ubiquitin-protein ligase. (819 aa)
	T265_08760	Uncharacterized protein. (1192 aa)
	T265_03964	Uncharacterized protein. (486 aa)
	T265_13452	Uncharacterized protein. (434 aa)
	T265_04098	Uncharacterized protein. (441 aa)
	T265_15372	BAR domain-containing protein. (205 aa)
	T265_13011	Uncharacterized protein. (652 aa)
	T265_04554	Protein tyrosine kinase. (688 aa)
	T265_00945	Uncharacterized protein. (760 aa)
	T265_12870	Protein kinase domain-containing protein. (1848 aa)
	T265_09265	BAR domain-containing protein. (173 aa)
	T265_07922	Receptor protein-tyrosine kinase. (1658 aa)
	T265_13536	Uncharacterized protein. (736 aa)
	T265_00947	Uncharacterized protein. (1046 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00945	T265_03964	A0A075A0Y8	A0A074ZPP6	Uncharacterized protein.	Uncharacterized protein.	0.792
T265_00945	T265_04098	A0A075A0Y8	A0A074ZTW5	Uncharacterized protein.	Uncharacterized protein.	0.711
T265_00945	T265_04554	A0A075A0Y8	A0A074ZZJ7	Uncharacterized protein.	Protein tyrosine kinase.	0.575
T265_00945	T265_07922	A0A075A0Y8	A0A075AA26	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.575
T265_00945	T265_12870	A0A075A0Y8	A0A075A183	Uncharacterized protein.	Protein kinase domain-containing protein.	0.575
T265_00945	T265_13011	A0A075A0Y8	A0A074ZZ51	Uncharacterized protein.	Uncharacterized protein.	0.967
T265_00945	T265_13452	A0A075A0Y8	A0A074ZTG2	Uncharacterized protein.	Uncharacterized protein.	0.759
T265_00945	T265_13536	A0A075A0Y8	A0A075AGG2	Uncharacterized protein.	Uncharacterized protein.	0.575
T265_00947	T265_04554	A0A075AJA4	A0A074ZZJ7	Uncharacterized protein.	Protein tyrosine kinase.	0.945
T265_00947	T265_07922	A0A075AJA4	A0A075AA26	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.945
T265_00947	T265_08760	A0A075AJA4	A0A074ZJ26	Uncharacterized protein.	Uncharacterized protein.	0.922
T265_00947	T265_09141	A0A075AJA4	A0A074ZHW0	Uncharacterized protein.	E3 ubiquitin-protein ligase.	0.908
T265_00947	T265_12870	A0A075AJA4	A0A075A183	Uncharacterized protein.	Protein kinase domain-containing protein.	0.945
T265_00947	T265_13011	A0A075AJA4	A0A074ZZ51	Uncharacterized protein.	Uncharacterized protein.	0.930
T265_00947	T265_13452	A0A075AJA4	A0A074ZTG2	Uncharacterized protein.	Uncharacterized protein.	0.522
T265_00947	T265_13536	A0A075AJA4	A0A075AGG2	Uncharacterized protein.	Uncharacterized protein.	0.945
T265_03964	T265_00945	A0A074ZPP6	A0A075A0Y8	Uncharacterized protein.	Uncharacterized protein.	0.792
T265_03964	T265_04098	A0A074ZPP6	A0A074ZTW5	Uncharacterized protein.	Uncharacterized protein.	0.913
T265_03964	T265_04554	A0A074ZPP6	A0A074ZZJ7	Uncharacterized protein.	Protein tyrosine kinase.	0.841
T265_03964	T265_07922	A0A074ZPP6	A0A075AA26	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.841