(6 nodes) Repression of WNT target genes, and Histone deacetylase network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_06726	Uncharacterized protein. (641 aa)
	T265_09811	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (505 aa)
	T265_05265	HMG box domain-containing protein. (631 aa)
	T265_09350	Uncharacterized protein. (981 aa)
	T265_00485	Uncharacterized protein. (1322 aa)
	T265_02604	Cir_N domain-containing protein. (261 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00485	T265_02604	A0A075A5K5	A0A075AI54	Uncharacterized protein.	Cir_N domain-containing protein.	0.949
T265_00485	T265_06726	A0A075A5K5	A0A074ZF55	Uncharacterized protein.	Uncharacterized protein.	0.946
T265_00485	T265_09350	A0A075A5K5	A0A075A598	Uncharacterized protein.	Uncharacterized protein.	0.926
T265_00485	T265_09811	A0A075A5K5	A0A074ZFG6	Uncharacterized protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.967
T265_02604	T265_00485	A0A075AI54	A0A075A5K5	Cir_N domain-containing protein.	Uncharacterized protein.	0.949
T265_02604	T265_06726	A0A075AI54	A0A074ZF55	Cir_N domain-containing protein.	Uncharacterized protein.	0.529
T265_02604	T265_09811	A0A075AI54	A0A074ZFG6	Cir_N domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.833
T265_05265	T265_06726	A0A074ZKC4	A0A074ZF55	HMG box domain-containing protein.	Uncharacterized protein.	0.960
T265_05265	T265_09350	A0A074ZKC4	A0A075A598	HMG box domain-containing protein.	Uncharacterized protein.	0.975
T265_05265	T265_09811	A0A074ZKC4	A0A074ZFG6	HMG box domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.508
T265_06726	T265_00485	A0A074ZF55	A0A075A5K5	Uncharacterized protein.	Uncharacterized protein.	0.946
T265_06726	T265_02604	A0A074ZF55	A0A075AI54	Uncharacterized protein.	Cir_N domain-containing protein.	0.529
T265_06726	T265_05265	A0A074ZF55	A0A074ZKC4	Uncharacterized protein.	HMG box domain-containing protein.	0.960
T265_06726	T265_09350	A0A074ZF55	A0A075A598	Uncharacterized protein.	Uncharacterized protein.	0.739
T265_06726	T265_09811	A0A074ZF55	A0A074ZFG6	Uncharacterized protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.948
T265_09350	T265_00485	A0A075A598	A0A075A5K5	Uncharacterized protein.	Uncharacterized protein.	0.926
T265_09350	T265_05265	A0A075A598	A0A074ZKC4	Uncharacterized protein.	HMG box domain-containing protein.	0.975
T265_09350	T265_06726	A0A075A598	A0A074ZF55	Uncharacterized protein.	Uncharacterized protein.	0.739
T265_09350	T265_09811	A0A075A598	A0A074ZFG6	Uncharacterized protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.935
T265_09811	T265_00485	A0A074ZFG6	A0A075A5K5	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Uncharacterized protein.	0.967