(42 nodes) Pentose phosphate pathway, and Glycolysis network (Opisthorchis viverrini)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	T265_16097	Pyruvate kinase; Belongs to the pyruvate kinase family. (64 aa)
	T265_11949	Glucose-6-phosphate isomerase; Belongs to the GPI family. (413 aa)
	T265_11268	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (212 aa)
	T265_09878	Pyruvate kinase; Belongs to the pyruvate kinase family. (570 aa)
	T265_15233	Pyruvate kinase; Belongs to the pyruvate kinase family. (630 aa)
	T265_08761	FBPase domain-containing protein; Belongs to the FBPase class 1 family. (300 aa)
	T265_10017	Triosephosphate isomerase. (252 aa)
	T265_09883	RNase H domain-containing protein. (748 aa)
	T265_07882	Uncharacterized protein. (618 aa)
	T265_07589	Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
	T265_10690	Uncharacterized protein. (231 aa)
	T265_10327	Uncharacterized protein. (431 aa)
	T265_10015	Triosephosphate isomerase. (241 aa)
	T265_07976	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (362 aa)
	T265_09766	Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (168 aa)
	T265_14006	Uncharacterized protein. (841 aa)
	T265_06695	Uncharacterized protein. (228 aa)
	T265_14585	Uncharacterized protein. (838 aa)
	T265_05102	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (370 aa)
	T265_05806	Glyceraldehyde-3-phosphate dehydrogenase. (338 aa)
	T265_04324	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (548 aa)
	T265_07435	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (482 aa)
	T265_06027	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (871 aa)
	T265_02250	Gp_dh_N domain-containing protein. (445 aa)
	T265_03262	Uncharacterized protein. (436 aa)
	T265_01568	Uncharacterized protein. (341 aa)
	T265_01146	Uncharacterized protein. (839 aa)
	T265_04184	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (576 aa)
	T265_12656	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (243 aa)
	T265_00750	Uncharacterized protein. (603 aa)
	T265_00607	Phosphoglycerate kinase. (415 aa)
	T265_10014	Triosephosphate isomerase. (245 aa)
	T265_13130	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (330 aa)
	T265_07855	Uncharacterized protein. (589 aa)
	T265_00315	Pribosyltran_N domain-containing protein. (560 aa)
	T265_05363	Transket_pyr domain-containing protein. (646 aa)
	T265_02773	Phosphotransferase. (410 aa)
	T265_02505	Uncharacterized protein. (364 aa)
	T265_12933	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (760 aa)
	T265_12938	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (394 aa)
	T265_01837	Uncharacterized protein. (285 aa)
	T265_01634	Enolase_C domain-containing protein. (507 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00315	T265_00750	A0A075ACW0	A0A075A253	Pribosyltran_N domain-containing protein.	Uncharacterized protein.	0.956
T265_00315	T265_04324	A0A075ACW0	A0A074ZNG9	Pribosyltran_N domain-containing protein.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.453
T265_00315	T265_05102	A0A075ACW0	A0A074ZLM0	Pribosyltran_N domain-containing protein.	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	0.955
T265_00315	T265_05363	A0A075ACW0	A0A075AFE6	Pribosyltran_N domain-containing protein.	Transket_pyr domain-containing protein.	0.965
T265_00315	T265_06027	A0A075ACW0	A0A074ZTV8	Pribosyltran_N domain-containing protein.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.484
T265_00315	T265_09878	A0A075ACW0	A0A074Z476	Pribosyltran_N domain-containing protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.509
T265_00315	T265_09883	A0A075ACW0	A0A074Z8J5	Pribosyltran_N domain-containing protein.	RNase H domain-containing protein.	0.922
T265_00315	T265_10690	A0A075ACW0	A0A074ZCB3	Pribosyltran_N domain-containing protein.	Uncharacterized protein.	0.956
T265_00315	T265_11949	A0A075ACW0	A0A074YX36	Pribosyltran_N domain-containing protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.573
T265_00315	T265_12656	A0A075ACW0	A0A075A1G6	Pribosyltran_N domain-containing protein.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.538
T265_00315	T265_12933	A0A075ACW0	A0A075AIH3	Pribosyltran_N domain-containing protein.	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	0.541
T265_00315	T265_15233	A0A075ACW0	A0A074Z5Q7	Pribosyltran_N domain-containing protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.509
T265_00315	T265_16097	A0A075ACW0	A0A074YUA8	Pribosyltran_N domain-containing protein.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.509
T265_00607	T265_00750	A0A075A297	A0A075A253	Phosphoglycerate kinase.	Uncharacterized protein.	0.401
T265_00607	T265_01146	A0A075A297	A0A075A0G7	Phosphoglycerate kinase.	Uncharacterized protein.	0.675
T265_00607	T265_01568	A0A075A297	A0A074ZZ32	Phosphoglycerate kinase.	Uncharacterized protein.	0.755
T265_00607	T265_01634	A0A075A297	A0A075AIT6	Phosphoglycerate kinase.	Enolase_C domain-containing protein.	0.889
T265_00607	T265_02250	A0A075A297	A0A074ZWG3	Phosphoglycerate kinase.	Gp_dh_N domain-containing protein.	0.897
T265_00607	T265_02505	A0A075A297	A0A075AI82	Phosphoglycerate kinase.	Uncharacterized protein.	0.872
T265_00607	T265_02773	A0A075A297	A0A075AI13	Phosphoglycerate kinase.	Phosphotransferase.	0.757