(9 nodes) Sterol biosynthetic process network (Opisthorchis viverrini)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_09380	Uncharacterized protein. (940 aa)
	T265_15495	Uncharacterized protein. (177 aa)
	T265_11226	NAD_binding_1 domain-containing protein. (175 aa)
	T265_10018	Uncharacterized protein. (671 aa)
	T265_11156	Uncharacterized protein. (565 aa)
	T265_10222	Nudix hydrolase domain-containing protein. (417 aa)
	T265_06306	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (513 aa)
	T265_01752	Mevalonate kinase. (415 aa)
	T265_09631	Uncharacterized protein. (136 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_01752	T265_06306	A0A075A1L8	A0A074ZSU0	Mevalonate kinase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.855
T265_01752	T265_09380	A0A075A1L8	A0A074ZH50	Mevalonate kinase.	Uncharacterized protein.	0.993
T265_01752	T265_09631	A0A075A1L8	A0A075A4C0	Mevalonate kinase.	Uncharacterized protein.	0.548
T265_01752	T265_10018	A0A075A1L8	A0A074Z3X2	Mevalonate kinase.	Uncharacterized protein.	0.663
T265_01752	T265_10222	A0A075A1L8	A0A074ZE32	Mevalonate kinase.	Nudix hydrolase domain-containing protein.	0.811
T265_01752	T265_11156	A0A075A1L8	A0A074ZAK6	Mevalonate kinase.	Uncharacterized protein.	0.997
T265_01752	T265_15495	A0A075A1L8	A0A074YY51	Mevalonate kinase.	Uncharacterized protein.	0.980
T265_06306	T265_01752	A0A074ZSU0	A0A075A1L8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Mevalonate kinase.	0.855
T265_06306	T265_09380	A0A074ZSU0	A0A074ZH50	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.999
T265_06306	T265_09631	A0A074ZSU0	A0A075A4C0	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.647
T265_06306	T265_10018	A0A074ZSU0	A0A074Z3X2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.772
T265_06306	T265_10222	A0A074ZSU0	A0A074ZE32	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Nudix hydrolase domain-containing protein.	0.915
T265_06306	T265_11156	A0A074ZSU0	A0A074ZAK6	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.884
T265_06306	T265_15495	A0A074ZSU0	A0A074YY51	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.632
T265_09380	T265_01752	A0A074ZH50	A0A075A1L8	Uncharacterized protein.	Mevalonate kinase.	0.993
T265_09380	T265_06306	A0A074ZH50	A0A074ZSU0	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.999
T265_09380	T265_09631	A0A074ZH50	A0A075A4C0	Uncharacterized protein.	Uncharacterized protein.	0.546
T265_09380	T265_10018	A0A074ZH50	A0A074Z3X2	Uncharacterized protein.	Uncharacterized protein.	0.546
T265_09380	T265_10222	A0A074ZH50	A0A074ZE32	Uncharacterized protein.	Nudix hydrolase domain-containing protein.	0.804
T265_09380	T265_11156	A0A074ZH50	A0A074ZAK6	Uncharacterized protein.	Uncharacterized protein.	0.743