(11 nodes) Morphogenesis of embryonic epithelium network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_10631	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
	T265_15030	Uncharacterized protein. (691 aa)
	T265_15158	Uncharacterized protein. (1043 aa)
	T265_13947	Tyrosine-protein kinase. (1014 aa)
	T265_12862	Uncharacterized protein. (1083 aa)
	T265_01776	Tyrosine-protein kinase. (1163 aa)
	T265_01254	Suppressor of fused protein. (977 aa)
	T265_00214	Uncharacterized protein. (452 aa)
	T265_00055	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein. (354 aa)
	T265_04001	Uncharacterized protein. (662 aa)
	T265_03534	Uncharacterized protein. (1130 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00214	T265_01254	A0A075A3T2	A0A075A3E2	Uncharacterized protein.	Suppressor of fused protein.	0.628
T265_00214	T265_10631	A0A075A3T2	A0A074Z1L6	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.428
T265_00214	T265_15030	A0A075A3T2	A0A074Z823	Uncharacterized protein.	Uncharacterized protein.	0.525
T265_01254	T265_00214	A0A075A3E2	A0A075A3T2	Suppressor of fused protein.	Uncharacterized protein.	0.628
T265_03534	T265_15158	A0A075AHI5	A0A074ZD97	Uncharacterized protein.	Uncharacterized protein.	0.908
T265_10631	T265_00214	A0A074Z1L6	A0A075A3T2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Uncharacterized protein.	0.428
T265_15030	T265_00214	A0A074Z823	A0A075A3T2	Uncharacterized protein.	Uncharacterized protein.	0.525
T265_15158	T265_03534	A0A074ZD97	A0A075AHI5	Uncharacterized protein.	Uncharacterized protein.	0.908