(46 nodes) RNA polymerase II, holoenzyme network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_12794	RNA_pol_L_2 domain-containing protein. (267 aa)
	T265_13991	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1203 aa)
	T265_12507	PHD-type domain-containing protein. (758 aa)
	T265_14412	TFIID_20kDa domain-containing protein. (473 aa)
	T265_08010	CDC73_N domain-containing protein. (501 aa)
	T265_08087	Uncharacterized protein. (167 aa)
	T265_00138	Helicase ATP-binding domain-containing protein. (846 aa)
	T265_12508	Uncharacterized protein. (443 aa)
	T265_13195	FMN_red domain-containing protein. (786 aa)
	T265_01404	TAFII28 domain-containing protein. (277 aa)
	T265_12509	Uncharacterized protein. (417 aa)
	T265_10220	Uncharacterized protein. (840 aa)
	T265_00433	Uncharacterized protein. (232 aa)
	T265_10407	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (103 aa)
	T265_10570	Uncharacterized protein. (416 aa)
	T265_01621	TAFII55_N domain-containing protein. (462 aa)
	T265_15386	MAT1 domain-containing protein. (1203 aa)
	T265_13266	Uncharacterized protein. (667 aa)
	T265_05699	RPOLD domain-containing protein. (640 aa)
	T265_06245	RNA polymerase K / subunit. (136 aa)
	T265_04366	TAFH domain-containing protein. (725 aa)
	T265_13585	Uncharacterized protein. (496 aa)
	T265_04996	Integrase catalytic domain-containing protein. (972 aa)
	T265_14327	WD_REPEATS_REGION domain-containing protein. (318 aa)
	T265_05533	Uncharacterized protein. (766 aa)
	T265_09179	RPOL4c domain-containing protein. (260 aa)
	T265_06290	Uncharacterized protein. (763 aa)
	T265_06498	Uncharacterized protein. (825 aa)
	T265_09719	TPR_REGION domain-containing protein. (1256 aa)
	T265_06756	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (547 aa)
	T265_14113	Reverse transcriptase domain-containing protein. (1401 aa)
	T265_14216	CID domain-containing protein. (1149 aa)
	T265_07434	Uncharacterized protein. (145 aa)
	T265_07453	Uncharacterized protein. (253 aa)
	T265_14828	HTH TFE/IIEalpha-type domain-containing protein. (431 aa)
	T265_09412	Uncharacterized protein. (67 aa)
	T265_08694	Plus3 domain-containing protein. (828 aa)
	T265_14648	RNA polymerase Rpb8. (156 aa)
	T265_10196	Uncharacterized protein. (185 aa)
	T265_10740	Uncharacterized protein. (76 aa)
	T265_10984	Uncharacterized protein. (2803 aa)
	T265_10596	Uncharacterized protein. (429 aa)
	T265_10741	WD_REPEATS_REGION domain-containing protein. (727 aa)
	T265_00004	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1846 aa)
	T265_00261	Uncharacterized protein. (931 aa)
	T265_12604	Uncharacterized protein. (1267 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00004	T265_00138	A0A075AJW9	A0A075A7E3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Helicase ATP-binding domain-containing protein.	0.939
T265_00004	T265_00261	A0A075AJW9	A0A075AJW4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.954
T265_00004	T265_00433	A0A075AJW9	A0A075A221	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.969
T265_00004	T265_01404	A0A075AJW9	A0A075A2Q0	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TAFII28 domain-containing protein.	0.834
T265_00004	T265_01621	A0A075AJW9	A0A074ZYR4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TAFII55_N domain-containing protein.	0.714
T265_00004	T265_04366	A0A075AJW9	A0A074ZST7	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TAFH domain-containing protein.	0.714
T265_00004	T265_04996	A0A075AJW9	A0A074ZQI4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Integrase catalytic domain-containing protein.	0.944
T265_00004	T265_05533	A0A075AJW9	A0A074ZJB6	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.775
T265_00004	T265_05699	A0A075AJW9	A0A074ZV44	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOLD domain-containing protein.	0.968
T265_00004	T265_06245	A0A075AJW9	A0A074ZT17	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase K / subunit.	0.968
T265_00004	T265_06290	A0A075AJW9	A0A074ZH19	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.879
T265_00004	T265_06498	A0A075AJW9	A0A074ZG93	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.948
T265_00004	T265_06756	A0A075AJW9	A0A074ZFD8	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.936
T265_00004	T265_07434	A0A075AJW9	A0A074ZCM7	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.946
T265_00004	T265_07453	A0A075AJW9	A0A074ZCI3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.696
T265_00004	T265_08010	A0A075AJW9	A0A075A9R3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	CDC73_N domain-containing protein.	0.743
T265_00004	T265_08087	A0A075AJW9	A0A075A9L9	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.622
T265_00004	T265_08694	A0A075AJW9	A0A074Z885	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Plus3 domain-containing protein.	0.876
T265_00004	T265_09179	A0A075AJW9	A0A074ZHS0	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOL4c domain-containing protein.	0.968
T265_00004	T265_09412	A0A075AJW9	A0A074ZA99	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.968