(57 nodes) Regulation of MAPK cascade network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_02122	Protein kinase domain-containing protein. (959 aa)
	T265_02217	Uncharacterized protein. (318 aa)
	T265_01930	Uncharacterized protein. (216 aa)
	T265_01727	UDENN domain-containing protein. (1791 aa)
	T265_13642	ATG11 domain-containing protein. (1646 aa)
	T265_04245	MATH domain protein. (546 aa)
	T265_00896	UDENN FLCN/SMCR8-type domain-containing protein. (723 aa)
	T265_12535	Protein kinase domain-containing protein. (245 aa)
	T265_13337	Uncharacterized protein. (1193 aa)
	T265_01341	Uncharacterized protein. (412 aa)
	T265_09889	Uncharacterized protein. (270 aa)
	T265_09435	Integrase catalytic domain-containing protein. (3159 aa)
	T265_12534	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (478 aa)
	T265_02536	Uncharacterized protein. (637 aa)
	T265_00022	BZIP transcription factor. (760 aa)
	T265_00763	Uncharacterized protein. (535 aa)
	T265_00456	Uncharacterized protein. (398 aa)
	T265_04001	Uncharacterized protein. (662 aa)
	T265_13054	TNase-like domain-containing protein. (546 aa)
	T265_02352	C2H2-type domain-containing protein. (790 aa)
	T265_01746	Uncharacterized protein. (1777 aa)
	T265_00726	Uncharacterized protein. (551 aa)
	T265_09444	J domain-containing protein. (252 aa)
	T265_12536	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (499 aa)
	T265_09474	Uncharacterized protein. (142 aa)
	T265_12173	Uncharacterized protein. (157 aa)
	T265_10160	Protein kinase domain-containing protein. (1000 aa)
	T265_14858	Protein kinase domain-containing protein. (759 aa)
	T265_08008	Uncharacterized protein. (1345 aa)
	T265_07999	RH2 domain-containing protein. (361 aa)
	T265_15276	Uncharacterized protein. (123 aa)
	T265_14358	Uncharacterized protein. (148 aa)
	T265_07579	Uncharacterized protein. (442 aa)
	T265_10045	Uncharacterized protein. (1312 aa)
	T265_14139	Uncharacterized protein. (527 aa)
	T265_06673	Uncharacterized protein. (485 aa)
	T265_06464	Uncharacterized protein. (860 aa)
	T265_05863	Protein kinase domain-containing protein. (977 aa)
	T265_05641	Uncharacterized protein. (141 aa)
	T265_07694	ANK_REP_REGION domain-containing protein. (239 aa)
	T265_14138	UDENN domain-containing protein. (714 aa)
	T265_14129	Protein kinase domain-containing protein. (917 aa)
	T265_03319	Uncharacterized protein. (572 aa)
	T265_16260	Uncharacterized protein. (66 aa)
	T265_03268	Uncharacterized protein. (1570 aa)
	T265_03062	Uncharacterized protein. (858 aa)
	T265_13452	Uncharacterized protein. (434 aa)
	T265_02401	Protein kinase domain-containing protein. (2254 aa)
	T265_09662	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (502 aa)
	T265_09724	Protein kinase domain-containing protein. (1153 aa)
	T265_10176	Protein kinase domain-containing protein. (862 aa)
	T265_15196	Uncharacterized protein. (920 aa)
	T265_11967	Protein kinase domain-containing protein. (389 aa)
	T265_15277	Uncharacterized protein. (916 aa)
	T265_11114	Uncharacterized protein. (1298 aa)
	T265_15500	Uncharacterized protein. (702 aa)
	T265_16137	Protein kinase domain-containing protein. (164 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00022	T265_13337	A0A075A736	A0A075A259	BZIP transcription factor.	Uncharacterized protein.	0.483
T265_02122	T265_10176	A0A074ZWD3	A0A074Z3B9	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.458
T265_02122	T265_13452	A0A074ZWD3	A0A074ZTG2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.431
T265_03062	T265_13452	A0A074ZT48	A0A074ZTG2	Uncharacterized protein.	Uncharacterized protein.	0.541
T265_04245	T265_05863	A0A075A0I3	A0A074ZI84	MATH domain protein.	Protein kinase domain-containing protein.	0.445
T265_04245	T265_13337	A0A075A0I3	A0A075A259	MATH domain protein.	Uncharacterized protein.	0.514
T265_04245	T265_14358	A0A075A0I3	A0A074ZC39	MATH domain protein.	Uncharacterized protein.	0.518
T265_04245	T265_16137	A0A075A0I3	A0A074YUD7	MATH domain protein.	Protein kinase domain-containing protein.	0.445
T265_05863	T265_04245	A0A074ZI84	A0A075A0I3	Protein kinase domain-containing protein.	MATH domain protein.	0.445
T265_05863	T265_13452	A0A074ZI84	A0A074ZTG2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.453
T265_06464	T265_13452	A0A074ZGD6	A0A074ZTG2	Uncharacterized protein.	Uncharacterized protein.	0.976
T265_09724	T265_10176	A0A074Z4U7	A0A074Z3B9	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.481
T265_10045	T265_13452	A0A074ZEQ4	A0A074ZTG2	Uncharacterized protein.	Uncharacterized protein.	0.460
T265_10160	T265_10176	A0A074Z7H5	A0A074Z3B9	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.453
T265_10160	T265_13452	A0A074Z7H5	A0A074ZTG2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.431
T265_10176	T265_02122	A0A074Z3B9	A0A074ZWD3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.458
T265_10176	T265_09724	A0A074Z3B9	A0A074Z4U7	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.481
T265_10176	T265_10160	A0A074Z3B9	A0A074Z7H5	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.453
T265_10176	T265_12534	A0A074Z3B9	A0A075A614	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.411
T265_10176	T265_12536	A0A074Z3B9	A0A075AJP6	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.423