(22 nodes) Mitotic DNA damage checkpoint signaling network (Opisthorchis viverrini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T265_11218	Uncharacterized protein. (114 aa)
	T265_14653	Uncharacterized protein. (220 aa)
	T265_08599	Uncharacterized protein. (1188 aa)
	T265_08544	WD_REPEATS_REGION domain-containing protein. (860 aa)
	T265_08399	WW domain-containing protein. (1101 aa)
	T265_11217	Uncharacterized protein. (91 aa)
	T265_07924	Uncharacterized protein. (368 aa)
	T265_08733	Uncharacterized protein. (161 aa)
	T265_05628	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (815 aa)
	T265_13819	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (774 aa)
	T265_04950	U1-type domain-containing protein. (275 aa)
	T265_13509	Uncharacterized protein. (933 aa)
	T265_13071	Uncharacterized protein. (459 aa)
	T265_02103	PI3K/PI4K domain-containing protein. (4230 aa)
	T265_09218	Uncharacterized protein. (517 aa)
	T265_12502	Uncharacterized protein. (600 aa)
	T265_00347	Uncharacterized protein. (1449 aa)
	T265_02061	BRCT domain-containing protein. (1151 aa)
	T265_00205	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3232 aa)
	T265_06122	NIBRIN_BRCT_II domain-containing protein. (720 aa)
	T265_05790	ERCC4 domain-containing protein. (795 aa)
	T265_04386	Uncharacterized protein. (1966 aa)

Your Current Organism:

Opisthorchis viverrini

NCBI taxonomy Id: 6198
Other names: O. viverrini, Southeast Asian liver fluke

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T265_00205	T265_00347	A0A075AD54	A0A075A6C3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.690
T265_00205	T265_02061	A0A075AD54	A0A075A815	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	BRCT domain-containing protein.	0.771
T265_00205	T265_02103	A0A075AD54	A0A074ZWB6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	PI3K/PI4K domain-containing protein.	0.698
T265_00205	T265_04386	A0A075AD54	A0A075AGL6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.698
T265_00205	T265_05628	A0A075AD54	A0A074ZIZ6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.986
T265_00205	T265_05790	A0A075AD54	A0A075AEV1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	ERCC4 domain-containing protein.	0.734
T265_00205	T265_06122	A0A075AD54	A0A075AEG4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	NIBRIN_BRCT_II domain-containing protein.	0.989
T265_00205	T265_07924	A0A075AD54	A0A074ZAS8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.595
T265_00205	T265_08599	A0A075AD54	A0A074Z8Q4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.536
T265_00205	T265_09218	A0A075AD54	A0A075A5Q0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.948
T265_00205	T265_11217	A0A075AD54	A0A074ZAE5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.690
T265_00205	T265_11218	A0A075AD54	A0A074YZJ9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.690
T265_00205	T265_13071	A0A075AD54	A0A074ZU71	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.924
T265_00347	T265_00205	A0A075A6C3	A0A075AD54	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.690
T265_00347	T265_02061	A0A075A6C3	A0A075A815	Uncharacterized protein.	BRCT domain-containing protein.	0.686
T265_00347	T265_04386	A0A075A6C3	A0A075AGL6	Uncharacterized protein.	Uncharacterized protein.	0.409
T265_00347	T265_05628	A0A075A6C3	A0A074ZIZ6	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.558
T265_00347	T265_05790	A0A075A6C3	A0A075AEV1	Uncharacterized protein.	ERCC4 domain-containing protein.	0.415
T265_00347	T265_06122	A0A075A6C3	A0A075AEG4	Uncharacterized protein.	NIBRIN_BRCT_II domain-containing protein.	0.680
T265_00347	T265_08599	A0A075A6C3	A0A074Z8Q4	Uncharacterized protein.	Uncharacterized protein.	0.633